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Best NFL Player Prop Bets for New England Patriots vs. Buffalo Bills (2022)

by January 15, 2022
Devin Singletary

We get an AFC East rivalry for the final game on Saturday. These two teams split the regular-season series, but none of that matters as this is a win-or-go-home situation. The weather is calling for cold and windy which will certainly have an impact on how these teams play and the players perform.

View the best player prop bets for this week’s slate with our NFL Prop Bet Cheat Sheet >>


  • Opening Lines: Buffalo -4.5 o/u 43.5
  • Current Lines: Buffalo -4 o/u 44
  • Location: Highmark Stadium
  • Start Time: Saturday 8:15 p.m. EDT
  • TV: CBS
  • Last Meeting: December 26, 2021 —  Buffalo 33, New England 21

All props via FanDuel

Mac Jones Passing Yards o/u 209.5
Kudos to Mac Jones for getting to the playoffs in his rookie year, you can’t say that about any of the other rookie quarterbacks, especially for the criticism he took for how high he picked. This is going to be a tough spot for Jones going to cold and frigid Buffalo, and we’ve seen how’s he’s performed in some tough weather. It won’t be a three-pass attempt night like the last time he played in Buffalo but more similar to the 145 yard performance and two interceptions like the last matchup.

Pick: Under 209.5

Josh Allen Touchdown Passes O/U  1.5

Allen has played three career games against the Patriots in Buffalo, do you know how many touchdowns passes he’s thrown? One, and that was this year. This is going to be a battle in trenches no matter who many blue pills Allen takes before this game. If he’s going to throw one, it might come from some broken coverage because he’s a guy that desires to run the ball in the red zone more than pass.

Pick: Under 1.5

Devin Singletary Rushing Yards O/U 62.5
It took some time, but finally, Devin Singletary is the RB1 in Buffalo. He has 19 or more carries in three of his last four games and averaging 4.6 yards or more yards per carry in his previous two games. The frigid Buffalo weather will continue to play a theme,  with the Bills relying on the ground game get and Singletary will get more than enough work to hit that over.

Pick: Over 62.5

Damien Harris Anytime TD
If the Pats get into the end zone, you bet they’re handing it off to Harris. He has four touchdowns against the Bills this year, and he was the reason New England stayed in that last matchup.

Pick: Damien Harris Anytime TD

Bet $10, Win $200 if Your Team Scores a TD >>

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