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MLB Moneyline, Over/Under, Run Line Odds & Matchups for Friday (4/22)

Jose_Ramirez

We’ve compiled odds from all of the major US sportsbooks to provide you a range of odds, as well as our consensus odds for today’s slate of MLB action. You can find moneyline, over/under, and run line odds along with each MLB matchup of the day.

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What is Betting the Run Line?
The run line is a set of odds bookmakers use to balance out MLB betting action by “handicapping” the favorite while boosting the underdog. The standard run line is 1.5, which means that bettors can choose to bet on the underdog +1.5, or the favorite -1.5. The odds on these wagers are quite different from the straight moneyline odds, with the moneyline underdog turning into the run line favorite.

What is an Over/Under Bet?
Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 8.5 runs and you bet Over, you will need the combined score of both teams to be 9 runs or higher to win your bet.

What is a Moneyline Bet?
A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

CTAs

Pirates @ Cubs
04/22/22 2:20 PM EDT – MLBN

View Matchup

PARTICIPANTS AND SELECTIONS

PIRATES
6-7
+145
+145
+145
+144
+140
+145
+145
+150
+145
+145
+145
+143
NL

CUBS
6-7
-175
-175
-175
-172
-160
-175
-175
-170
-167
-167
-167
-167
NL

Cardinals @ Reds
04/22/22 6:40 PM EDT

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PARTICIPANTS AND SELECTIONS

CARDINALS
7-4
-130
-125
-125
-126
-125
-128
-130
-130
-127
-130
-130
-127
NL

REDS
2-11
+110
+105
+105
+108
+105
+110
+110
+110
+110
+114
+106
+106
NL

Brewers @ Phillies
04/22/22 7:05 PM EDT

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PARTICIPANTS AND SELECTIONS

BREWERS
8-5
+110
+105
+105
+108
+105
+105
+110
+110
+110
+110
+110
+110
NL

PHILLIES
5-8
-128
-125
-125
-126
-125
-128
-130
-130
-132
-132
-132
-132
NL

Guardians @ Yankees
04/22/22 7:05 PM EDT

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PARTICIPANTS AND SELECTIONS

GUARDIANS
7-5
+170
NL
NL
+168
+170
+170
+170
+175
NL
NL
NL
NL
NL

YANKEES
7-6
-200
NL
NL
-200
-200
-213
-204
-200
NL
NL
NL
NL
NL

Rockies @ Tigers
04/22/22 7:10 PM EDT

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PARTICIPANTS AND SELECTIONS

ROCKIES
8-4
+120
+125
+125
+120
+125
+120
+120
+120
+120
+120
+120
+120
NL

TIGERS
5-7
-139
-150
-150
-142
-145
-143
-141
-140
-139
-139
-139
-148
NL

Red Sox @ Rays
04/22/22 7:10 PM EDT

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PARTICIPANTS AND SELECTIONS

RED SOX
6-7
+120
+115
+115
+120
+115
+120
+120
+120
+123
+123
+123
+120
NL

RAYS
7-6
-143
-140
-140
-142
-135
-143
-141
-140
-143
-143
-143
-143
NL

Marlins @ Braves
04/22/22 7:20 PM EDT

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PARTICIPANTS AND SELECTIONS

MARLINS
5-7
+125
+125
+125
+126
+125
+130
+125
+125
+132
+132
+132
+132
NL

BRAVES
6-8
-148
-155
-155
-148
-145
-154
-145
-145
-155
-155
-155
-165
NL

Blue Jays @ Astros
04/22/22 8:10 PM EDT

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PARTICIPANTS AND SELECTIONS

BLUE JAYS
8-5
+145
+140
+140
+138
+145
+145
+145
+150
+143
+143
+143
+143
NL

ASTROS
6-6
-167
-165
-165
-164
-165
-175
-175
-170
-167
-167
-167
-175
NL

White Sox @ Twins
04/22/22 8:10 PM EDT

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PARTICIPANTS AND SELECTIONS

WHITE SOX
6-6
-108
-105
-105
-108
-105
-105
-110
-110
-108
-108
-108
-113
NL

TWINS
5-8
-110
-115
-115
-108
-115
-115
-110
-110
-108
-108
-108
-108
NL

Orioles @ Angels
04/22/22 9:38 PM EDT

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PARTICIPANTS AND SELECTIONS

ORIOLES
4-9
+160
+155
+155
+160
+155
+160
+160
+160
+165
+165
+165
+165
NL

ANGELS
8-5
-190
-190
-190
-190
-180
-188
-196
-180
-195
-195
-195
-200
NL

Royals @ Mariners
04/22/22 9:40 PM EDT

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PARTICIPANTS AND SELECTIONS

ROYALS
5-6
+120
+115
+115
+120
+120
+120
+120
NL
+114
+114
+114
+114
NL

MARINERS
7-6
-140
-140
-140
-142
-140
-143
-141
NL
-132
-132
-132
-137
NL

Mets @ Diamondbacks
04/22/22 9:40 PM EDT

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PARTICIPANTS AND SELECTIONS

METS
10-4
-130
-130
-130
-134
-130
-133
-130
-130
-129
-129
-129
-136
NL

DIAMONDBACKS
5-8
+110
+105
+105
+114
+110
+110
+110
+110
+110
+110
+110
+110
NL

Rangers @ Athletics
04/22/22 9:40 PM EDT

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PARTICIPANTS AND SELECTIONS

RANGERS
3-9
-128
-125
-125
NL
-130
-128
-130
-130
-125
-125
-125
-134
NL

ATHLETICS
8-6
+110
+105
+105
NL
+110
+110
+110
+110
+108
+108
+108
+108
NL

Dodgers @ Padres
04/22/22 9:40 PM EDT

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PARTICIPANTS AND SELECTIONS

DODGERS
9-3
-175
-185
-185
-178
-165
-175
-175
-170
-177
-177
-177
-186
NL

PADRES
9-5
+150
+150
+150
+150
+145
+145
+145
+150
+150
+150
+150
+150
NL

 

CTAs


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