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Philadelphia Eagles at Buffalo Bills Odds & Game Pick

by October 25, 2019

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The Bills improved to 5-1 this season following a 31-21 home victory over Miami last Sunday. Buffalo’s only loss came against the undefeated Patriots, and the Bills had a chance to make things interesting late in that game. This is an interesting AFC-NFC clash between a pair of teams that can be considered opposites in many ways. The Bills get things done on defense, ranking top five in most crucial defensive categories. 

Meanwhile, the Eagles have struggled on defense throughout most of the season, especially against the pass. Philadelphia has allowed 7.5 yards per pass attempt in 2019, which ranks 26th in the NFL. Their rushing defense has otherwise been solid, yielding only 3.7 yards per carry, ranking top-10 in the league. Their glaring weakness comes from a discombobulated secondary. Not having offensive tackle Jason Peters (ruled out for this game) doesn’t help on the other side of the ball, either. 

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  • Opening Lines: The spread has stayed put from opening at Bills -2.5. The over/under marginally jumped after opening at 41.5.
  • Current Line: Bills -2.5 at FanDuel Sportsbook
  • O/U: 42.5 at FanDuel Sportsbook
  • Location: New Era Stadium – Buffalo, NY
  • Start Time: 1:00pm ET
  • Television: FOX 
  • Last Meeting: December 13, 2015 – Eagles defeated Bills 23-20 in Philadelphia

View consensus picks from 100+ experts for the Eagles at Bills >>


What’s the best way to handle this game? The Bills seem more polished on both sides of the ball at this point in the season, but Philadelphia arguably maintains an edge in terms of raw talent on their roster. The Eagles got trounced 38-20 and 37-10 against Minnesota and Dallas respectively over their past two games, so they’ll have a chip on their shoulder entering this contest. Is Buffalo’s 5-1 record a mirage, or are the Bills for real? We should get more clarity on Sunday. 


  • The Bills are 11-8 to the over at home since 2017.
  • The Bills are 1-4 ATS as a home favorite since 2018. 
  • The Eagles are 18-12 ATS in non-division games over the last two years.
  • The Eagles are 8-4 to the over as a road underdog since 2017. 

Prop Bets

Carson Wentz UNDER 1.5 Passing Touchdowns
Not only will Carson Wentz have to deal with a tough Buffalo defense and a beat-up offensive line, but mother nature is against him as well. It should be rainy and windy on Sunday afternoon, and Wentz’s performance could suffer as a result. Go ahead and consider a play on under 235 passing yards for Wentz as well. 

Bottom Line

We are looking at windy conditions (20+ mph) with a good chance of rain (75%) in Buffalo on Sunday afternoon. That could make it difficult for each of these teams to move the ball with regularity, especially in the passing game. It’s always tempting to play the under in a Buffalo game, and the weather should help here. 

Pick: Under 42.5 at FanDuel Sportsbook

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Check out our other NFL Sports Betting Guides for Week 8

Cincinnati Bengals at Los Angeles Rams (-11.5)
Los Angeles Chargers at Chicago Bears (-4)
New York Jets at Jacksonville Jaguars (-6)
Tampa Bay Buccaneers at Tennessee Titans (-2.5)
Seattle Seahawks at Atlanta Falcons (+7)
New York Giants at Detroit Lions (-6)
Denver Broncos at Indianapolis Colts (-4.5)
Oakland Raiders at Houston Texans (-6.5)
Arizona Cardinals at New Orleans Saints (-10.5)
Cleveland Browns at New England Patriots (-11)
Carolina Panthers at San Francisco 49ers (-5)
Green Bay Packers at Kansas City Chiefs (+4.5)
Miami Dolphins at Pittsburgh Steelers (-14)

Spencer Limbach is a featured writer at BettingPros and FantasyPros. For more from Spencer, check out his archive and follow him @spencer_jl.

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