Best College Football Parlays & Picks: Week 10 (2026)

Week 10 brings us several huge top-25 matchups on Saturday’s college football slate. It starts at noon with the annual “Holy War” game between No. 9 BYU vs. No. 3 Utah, plus a top-20 SEC tilt between No. 7 Texas and No. 18 Missouri.

The late-afternoon slate follows with huge matchups: No. 5 Alabama vs. No. 14 LSU and No. 23 Oregon vs. No. 12 Ohio State. Then, starting at 6:15 p.m. ET, it’s No. 6 Kentucky vs. No. 13 Tennessee, followed up by No. 1 Miami vs. No. 11 Notre Dame and No. 2 Georgia vs. No. 10 Ole Miss.

Last week’s Best College Football Parlays & Picks: Week 9 (2026) unfortunately settled 0-3. Let’s aim for a better result ahead of the Week 10 mega slate with 3 parlays at plus odds.

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College Football Parlays for Week 10

(Odds courtesy of DraftKings Sportsbook)

Utah Moneyline/Under 48.5 (+190)

Devon Dampier and the Utah Utes will look to remain undefeated at home against their in-state rival during Saturday’s top-10 matchup. Both teams have top-25 defenses, and Utah is coming off a dominant 49-25 road win over Cincinnati.

The Cougars have looked vulnerable for the last few weeks since their season-defining win over Notre Dame. BYU’s loss to UCF was followed up by a narrow 27-20 win over Arizona State.

Utah’s run game is lethal, averaging 5.7 YPC with 20 rushing touchdowns this season. BYU has allowed 9 touchdowns to its previous 3 opponents. The Cougars are only averaging 2.5 YPC in their last 2 appearances, while committing multiple turnovers.

Utah has a great defense, holding opponents to 3.6 YPC this season and 0 passing touchdowns against Houston and Cincinnati in its last 2 games played.

Let’s craft a Big 12 Same Game Parlay. Bet Utah moneyline (-192) and Under 48.5 (-105) to get this parlay to +190 odds.

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Alabama +6.0/Kentucky +7.0 (+255)

Alabama has been feast or famine on the spread this season. The Crimson Tide have a prime opportunity to improve their stock with a road win over No. 14 LSU on Saturday afternoon.

QB Keelon Russell has had a couple of bad performances leading to losses for Alabama. Expect that to change against an LSU defense that has allowed explosive plays to Ole Miss and Kentucky in both of their biggest games played this season, each resulting in losses.

Both teams are coming off a bye ahead of this game in Baton Rouge. +6 feels like too many points to give to a team of Alabama’s caliber. The Crimson Tide are 4-4 ATS but have covered +6.0 in 7 of 8 games this season.

Alabama has beaten LSU outright in 4 of their past 5 head-to-head matchups. Let’s plug Alabama +6.0 into the first leg of this SEC underdog parlay at -108 odds.

Next, we’re going to continue backing Kentucky. The Wildcats are a profitable spread team, going 7-1 ATS this season, while Tennessee is just 4-4 ATS, losing to Texas at home and blowing a late lead in their last game played during a 27-24 road loss to South Carolina.

Kentucky has gone 4 straight games without committing a turnover. Tennessee’s defense is the backbone of its team, but the Wildcats’ ability to finish drives with points means we’re going to take Kentucky +7.0 at -118 odds to boost this parlay to +255 odds.

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Miami +7.5/Georgia (+193)

The nation’s top-ranked team, Miami, will look to extend its unbeaten mark with a tough road trip to South Bend, taking on No. 11 Notre Dame. The Hurricanes narrowly avoided a big upset loss on the road against North Carolina in a high-scoring 38-35 victory in Week 9.

Odds have moved to Miami +7.5, largely because WR1 Malachi Toney is ruled out due to a high ankle sprain. This is a great value spot to back the Hurricanes, with QB Darian Mensah possessing a ridiculous 80.7 percent completion rate with 2,425 yards, 25 touchdowns, and 1 interception.

Miami still has star RB Mark Fletcher in the backfield. Notre Dame’s soft schedule, combined with Toney’s absence, means we get to back Mensah and the Hurricanes as a touchdown underdog on the road at +7.5.

Finally, we’re going to back Georgia to win in Oxford against Ole Miss on Saturday night. The Bulldogs, led by QB Gunner Stockton, have the upper hand in this game, facing a Rebels defense allowing 24 points per game (64th) this season.

Conversely, Georgia’s defense is stout, holding every opponent, excluding its lone loss to Auburn, to 20 or fewer points, ranked 11th in points allowed per game (14.9) in 2026.

Trinidad Chambliss is a stud at quarterback for Ole Miss. However, we saw the Rebels’ defense dig a huge hole early against Texas. It could be a similar situation in this matchup, so let’s insert Georgia moneyline at -175 odds.

As a result, this Miami +7.5/Georgia moneyline parlay gets us to +193 odds to close out our Week 10 college football parlays.

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