Best NFL Week 3 Ladder Bets: Picks & Predictions (2025)
We're coming off a monster betting weekend in the NFL, where we climbed two out of three ladders and netted +9.47 units with our Week 2 ladder bets. Let's stay hot with our top NFL Week 3 ladder bets. Below are three superstars who have favorable matchups and are primed to go nuclear from a statistical standpoint.
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Best NFL Week 3 Ladder Bets
(Odds courtesy of DraftKings Sportsbook)
Ja'Marr Chase Receiving Yards
Let's get it started in the Twin Cities on Sunday, where the Bengals (2-0) and the Vikings (1-1) square off in a battle of backup quarterbacks. Jake Browning takes over for Cincinnati, while Minnesota will ride with Carson Wentz. Kick-off is scheduled for 1:00 p.m. ET from U.S. Bank Stadium in Minneapolis, MN.
This is a great buy-low spot on Ja'Marr Chase. His yardage total sits at just 70.5 yards. He has gone over this number in nine out of his last 10 outings. Now, let's address the elephant in the room, which is Browning and his promotion to the starter's spot following Joe Burrow's toe injury. Browning didn't skip a beat in relief last weekend, going 21-for-32 (65.6%) and amassing 241 yards and two touchdowns. Back in 2023, Browning made seven starts and averaged 266.9 passing yards per game. He's plenty serviceable.
On the flip side, this Vikings defense, which is regarded as one of the better units in the NFL, is banged up at the moment and not playing great. Safeties Harrison Smith (illness) and Theo Jackson (hip), as well as outside linebacker Andrew Van Ginkel (concussion), were all limited in practice earlier in the week. Minnesota's secondary has posted a Pro Football Focus (PFF) coverage grade of 61.2, which ranks 30th in the NFL. Chase could explode through these disrespectfully low lines and have a big day.
CeeDee Lamb Receiving Yards
Sunday's total between the Cowboys (1-1) and the Bears (0-2) has already broken through the seven-touchdown barrier and now sits at 50.5 points. This is a great sign for bettors looking to play overs, since sportsbooks are expecting plenty of points. Kick-off is set for 4:25 p.m. ET from Soldier Field in Chicago, IL.
There's an old saying: "If it ain't broke, don't fix it." We rode with CeeDee Lamb last week against the Giants, and he accumulated 112 yards on nine catches. In Week 1, he went for 110 yards on seven catches. He has cleared 90 yards in five consecutive games.
Lamb and this Dallas offense get another good matchup on Sunday afternoon. They'll take on a Chicago secondary that PFF has graded as dead last in coverage (36.1) through two weeks. They're allowing 234 passing yards per game (22nd), as well as letting opponents complete 75% of their pass attempts (29th). Look for the Dak Prescott-CeeDee Lamb connection to flourish on Sunday against a Jaylon Johnson-less Bears secondary.
Sam LaPorta Receiving Yards
The Week 3 action concludes with a clash of titans on Monday, as the Lions (1-1) take on the Ravens (1-1). This Monday Night Football showdown kicks off at 8:15 p.m. ET from M&T Bank Stadium in Baltimore, MD.
If you thought the total for the Cowboys versus Bears matchup was high, well, I have news for you, as this contest sits even higher at 52.5 points. Detroit's high-octane offense found its footing last weekend against Chicago, with Jared Goff passing for 334 yards in a 52-21 rout in Motown. Interestingly, Sam LaPorta only had 26 yards on three catches and four targets. However, this was the only game in his last seven where he didn't eclipse 40 yards. He's heavily involved in the passing attack, averaging 7.4 targets in his last seven regular-season games.
Now, there's no denying that the Ravens defense is a top-tier unit. But we have seen them get shredded this season, like in Week 1 when Josh Allen put up 394 passing yards against them. Baltimore is now 31st in passing yards allowed per game (298). Both of these organizations are stacked with offensive talent and have no issue turning any game into a barnburner. I expect to see all of Detroit's weapons get involved, but I think it's best to play LaPorta at these relatively low lines.