College Football Week 11 Odds, Picks & Predictions: Louisville vs. Clemson (2022)

Let’s take a look at the College Football Week 11 odds, picks, and predictions for this week’s game Louisville vs. Clemson.

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College Football Week 11 Odds, Picks & Predictions: Louisville vs. Clemson

Falling all the way to #10 in this week’s official CFP ranking, the Clemson Tigers come into the week off of their first loss of the season, a 14-35 defeat on the road at Notre Dame. For the first time this season, the Tigers were unable to overcome the poor play of QB DJ Uiagalelei who finished the game with 191 yards and one touchdown (one interception). The front seven was also gashed, allowing 263 yards on the ground en route to 35 points from the Fighting Irish.

As for Louisville, a 2-3 start to the season has been followed up with four straight wins, as the offense has finally started to click scoring 35 points per game in the process. A closer look shows that outside of an opening game loss on the road at Syracuse, the Cardinals have lost by a combined five points this season.

I like for Louisville to hold their own in this one, keeping this game well within the #.

Louisville +7.5

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