College Football Week 6 Odds, Picks & Predictions: Friday (10/7)

Let’s take a look at the College Football Week 6 odds, picks, and predictions for Friday’s games.

Here are other game previews for Week 6:

And check out our other Week 6 College Football betting content:

Check out Thor Nystrom’s Week 6 College Football Power Rankings >>

College Football Week 6 Odds, Picks & Prediction: Friday

Nebraska vs. Rutgers

This week’s Big Ten Conference schedule gets underway one day earlier as Nebraska travels to Rutgers on Friday night in Piscataway, New Jersey.

All five games of the series have been won by the visiting Cornhuskers (2-3, 1-1), with their most recent victory occurring on the road on December 18, 2020. Since then, Nebraska hasn’t won a game away from Lincoln, suffering six straight losses now. Nebraska just defeated Indiana 35-21 at home, snapping a nine-game losing streak to FBS opponents. It was Mickey Joseph’s first victory as the team’s interim coach after Scott Frost was sacked three games into the season.

After going undefeated prior to Big Ten competition, Rutgers (3-2, 0-2) has had a difficult start to league action. The previous week, the Scarlet Knights lost 27-10 to Iowa at home before losing 49-10 to Ohio State on Saturday. In fact, the Scarlett Knights have now scored just 58 points in total through their four FBS games.

While this total has already ticked down, I don’t think far enough for two putrid offenses.

Under 49


Houston vs. Memphis

Memphis just defeated Temple 24-3 last week as they head into this AAC rivalry game. The Tigers raced to victory despite a sloppy first half in which they were held without a point for the first time since 2017. With a victory on Friday, the Tigers (4-1, 2-0 AAC) can maintain their lead in the standings of the conference and all but eliminate Houston’s prospects of returning to the league championship game.

In the fourth quarter last week, Houston (2-3, 0-1 AAC) scored 14 straight points before Tulane scored a TD with 39 seconds left to tie the game. In overtime, the Cougars chose to receive the ball first and attempted a field goal, but Tulane ultimately prevailed thanks to a game-winning touchdown pass during their possession.

In the losing effort, quarterback Clayton Tune threw for 208 yards and two touchdowns, becoming just the fourth Houston player in history to achieve 10,000 career total yards. In their 30-game history with the Tigers, Houston has prevailed in 16 of the contests, with exactly half coming home and away. I think much of this line is built on teams of the past, something Houston coach Dana Holgerson certainly wishes he had.

Memphis rolls at home.

Memphis -3


Colorado State vs. Nevada

On the surface, this play makes no sense. Nevada, the home team, is 2-3 and has beaten two FBS teams. Colorado State is 0-4, hasn’t come within 15 points of any opponent, and lost 41-10 to an FCS team last time out.

This is CSU HC Jay Norvell’s return to Nevada – he recruited a majority of the players on Nevada’s roster. Norvell also took 11 Nevada players with him in the transfer portal, along with most of its coaching staff. Arguably, CSU knows Nevada’s personnel better than any opponent will know any other’s all season.

And speaking to CSU’s personnel, it will be stronger on Friday than perhaps at any point all season. Norvell’s slow start there is partly attributable to shoddy OL play: Despite playing one less game than most teams, CSU leads the nation with 25 sacks allowed and is last in the country in rushing YPG and YPC.

Impossible to get the Air Raid going if you’re allowing six sacks a game, amirite? CSU’s offensive line was decimated by injuries over the first month. During the 0-4 start, they started a different offensive line configuration each time. But reports out of CSU this week suggest that the Rams are getting back both starting offensive tackles from injuries this week.

Not only that, but CSU believes there’s a decent chance they’ll be getting back four previously-injured defensive starters for this game – a DT, a CB, and both safeties.

Nevada’s fluky 2-0 start came courtesy of opening the season against New Mexico State and Texas State, two of the FBS’ 15-worst teams. Since then, Nevada has lost to FCS Incarnate Word (by 14), Iowa (by 27), and Air Force (28 points).

With an intact offensive line, you take CSU’s talent over Nevada’s all day long. This is a circled game for CSU’s staff. And that staff – and 11 of its players – know the opponent like the back of their hand. Give us the Rams to win their first game of the year.

Colorado State +3.5

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