Jacksonville Jaguars at Indianapolis Colts Odds & Game Pick

In the first matchup between these AFC South foes this season, the 4-5 Jacksonville Jaguars head to Indianapolis to face the 5-4 Colts. Jacksonville is fresh off a bye after playing in London the week before, while Indianapolis has lost two straight.

Both teams are also getting their starting quarterbacks back under center, making this an interesting divisional battle.

Special Offer: Bet $1 and win $100 if Tom Brady completes a pass against the Eagles >>

Jaguars vs Colts Odds and Info

All odds taken from FanDuel Sportsbook.

  • Opening Lines: IND -2.5, O/U 43.5
  • Moneyline: JAX: (+134) | IND: (-154)
  • Spread: JAX: +3 (-110) | IND: -3 (-110)
  • Total: 44 – Over: (-110) | Under: (-110)
  • Location: Lucas Oil Stadium – Indianapolis, IN
  • Start Time: 1 pm ET
  • Coverage: CBS

Injuries

  • Jacksonville Jaguars: OT Cam Robinson (Q), C Brandon Linder (Q), DE Calais Campbell (Q)
  • Indianapolis Colts: WR T.Y. Hilton (D), TE Mo Alie-Cox (Q), RB Jordan Wilkins (Q), TE Jack Doyle (Q)

View consensus picks from 100+ experts for the Jaguars at Colts >>

Overview

“Minshew Mania” was fun while it lasted, but Nick Foles is back for the Jaguars this week after getting hurt in Week 1. It is unknown how much chemistry there is built between Foles and the rest of this offense, so there could be some kinks to work out early. No matter who is taking snaps, we know they will be giving the ball to Leonard Fournette early and often. The talented running back has totaled at least 20 touches in six of his last seven games, making him a true bell-cow back. Defensively, Jacksonville has been inconsistent this season, allowing 371.3 yards per game, including 129.6 on the ground. They will need to generate pressure in this game if they hope to win.

The Colts are also returning a quarterback this week, after Jacoby Brissett injured his knee early two weeks ago, which then resulted in two losses to sub-par AFC opponents under Brian Hoyer. Brissett’s return will be big for this offense, but it looks like they will still be without star wide receiver T.Y. Hilton. To replace his production, the Colts will utilize their cast of tight ends often, as well as pound the rock with Marlon Mack behind their big offensive line. The Colts will look to break the trend and defeat the Jaguars at home for the first time since 2014.

Trends

  • Every team playing in London this season has lost their next game both against the spread (ATS) and straight up.
  • Jacksonville is 7-0-1 ATS in its last eight games against Indianapolis.
  • The total has hit the under in seven of Jacksonville’s last eight road game against Indianapolis.
  • Indianapolis is 5-1 straight up in its last six home games against Jacksonville.
  • The Colts lead the all-time series with the Jaguars, 23-13.
  • Last Meeting: December 2, 2018 — The Jaguars defeated the Colts, 6-0, at TIAA Bank Field.

Prop Bet

All odds taken from FanDuel Sportsbook.

Winning Margin (4-Way) Indianapolis Colts by 1-13 Pts (+150)
I’ll discuss below why I believe the Colts will win, but this prop is essentially a more profitable moneyline bet. Every game for the Colts has been decided by one score, and this is not the game for a blowout on either side, with both teams playing unexciting offense and decent defense. The Colts will win narrowly at home, and this prop is the best way to bet on the game, with +150 return.

Bottom Line

When the Jaguars have lost this season, it has been because they faced teams that ran the ball well against them. They have given up an average of 168.8 rushing yards in their five losses, with all give games having over 100 rushing yards allowed. The Colts are a team that can take advantage of this, with Marlon Mack, their tight ends, and the offensive line. This game may be a low-scoring, unexciting affair in both quarterbacks’ returns, but the Colts will barely cover the spread because of the men upfront.

Pick: Indianapolis Colts -3

FanDuel Sportsbook: View our review and access special sports betting offers >>

Check out our other NFL Sports Betting Guides for Week 10

Buffalo Bills at Miami Dolphins (+6.5)
Dallas Cowboys at Detroit Lions (+7)
New York Jets at Washington Redskins (-2.5)
Houston Texans at Baltimore Ravens (-4.5)
Atlanta Falcons at Carolina Panthers (-4.5)
New Orleans Saints at Tampa Bay Buccaneers (+5.5)
Denver Broncos at Minnesota Vikings (-10)
Arizona Cardinals at San Francisco 49ers (-9)
New England Patriots at Philadelphia Eagles (+4)
Cincinnati Bengals at Oakland Raiders (-11.5)
Chicago Bears at Los Angeles Rams (-6)
Kansas City Chiefs at Los Angeles Chargers (+4)

Zach Brunner is a featured writer at BettingPros. For more from Zach, check out his archive and follow him @FantasyFlurry.