March Madness Odds First Round (NCAA Tournament 2022)

March Madness is here!

Here are the odds for the first round of the NCAA Basketball Tournament, commonly referred to March Madness. All First Four and Round of 64 odds are based on BettingPros consensus odds at the time of publishing. For the latest odds, please visit our live odds page. We will update once the First Four matchups wrap up. 

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First Four

#11 Rutgers vs. #11 Notre Dame

Spread: -0.5 Rutgers
Total: 132
ML: -125/+102

#12 Wyoming vs. #12 Indiana

Spread: -4 Indiana
Total: 132.5
ML: +145/-170

#16 Wright State vs. #16 Bryant

Spread: -2
Total: 152
ML: -125/+105

#16 Texas Southern vs. #16 Texas A&M-CC

Spread: -3.5 Texas Southern
Total: 135.5
ML: -165/+125

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West Region

#1 Gonzaga vs. #16 Georgia State 

Spread: -25.5
Total: 148.5
ML: -12500/+3500

#8 Boise State vs. #9 Memphis

Spread: -1.5 Memphis
Total: 136.5
ML: -124-+104

#5 UConn vs. #12 New Mexico State

Spread: -6.5 Uconn
Total: 134.5
ML: -315/+255

#4 Arkansas vs. #13 Vermont

Spread: -6.5 Arkansas
Total: 141.5
ML: -278/+230

#2 Alabama vs. #11 Rutgers/Notre Dame

Will be updated following play-in game.

#3 Texas Tech vs. #14 Montana State

Spread: -16 Texas Tech
Total: 135
ML: -3333/+13000

#7 Michigan State vs. #10 Davidson

Spread: -1.5 Michigan State
Total: 142
ML: -125/+105

#2 Duke vs. #15 CS Fullerton

Spread: -18 Duke
Total: 143.5
ML: -3333/+1300

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South Region

#1 Arizona vs. #16 Wright State/Bryant

Will be updated following play-in game.

#8 Seton Hall vs. #9 TCU

Spread: -1 Seton Hall
Total: 129.5
ML: -114/-104

#5 Houston vs. #12 UAB

Spread: -8.5 Houston
Total: 141.5
ML: -400/+320

#4 Illinois vs. #13 Chatanooga

Spread: -8 Illinois
Total: 138
ML: -420/+330

#6 Colorado State vs. #11 Michigan

Spread: -2 Michigan
Total: 139.5
ML: +110/-130

#3 Tennessee vs. #14 Longwood

Spread: -16.5 Tennessee
Total: 135
ML: -2500/+1150

#7 Ohio State vs. #10 Loyola Chicago

Spread: -1 Loyola Chicago
Total: 136.5
ML: -125/+105

#2 Villanova vs. #15 Delaware

Spread: -16.5 Villanova
Total: 134
ML: -2000/+1500

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Midwest Region

#1 Kansas vs. #16 Texas Southern/Texas A&M-CC

Will be updated following play-in game.

#8 San Diego State vs. #9 Creighton

Spread: -0.5 San Diego State
Total: 119.5
ML: -109/-109

#5 Iowa vs. #12 Richmond

Spread: -9.5 Iowa
Total: 154.5
ML: -625/+450

#4 Providence vs. #13 South Dakota State

Spread: -2.5 Providence
Total: 142.5
ML: -143/+120

#6 LSU vs. #11 Iowa State

Spread: -5 LSU
Total: 129
ML: -200/+165

#3 Wisconsin vs. #14 Colgate

Spread: -8.5 Wisconsin
Total: 140
ML: -455/+340

#7 USC vs. #19 Miami (FL)

Spread: -1.5 USC
Total: 142
ML: -125/+105

#2 Auburn vs. #15 Jacksonville State

Spread: -16.5 Auburn
Total: 142.5
ML: -5000/+1400

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East Region

#1 Baylor vs. #16 Norfolk State

Spread: -20 Baylor
Total: 138
ML: -3333/+1300

#8 North Carolina vs. #9 Marquette

Spread: -3 North Carolina
Total: 151.5
ML: 155/+130

#5 Saint Mary’s vs. #12 Wyoming/Indiana

Will be updated following play-in game.

#4 UCLA vs. #13 Akron

Spread: -15 UCLA
Total: 134
ML: -1667/+950

#6 Texas vs. #11 Virginia Tech

Spread: -1.5 Texas
Total: 125
ML: -120/+100

#3 Purdue vs. #14 Yale

Spread: -16 Purdue
Total: 143.5
ML: -2000/+1000

#7 Murray State vs. #10 San Francisco

Spread: -1.5 San Francisco
Total: 141
ML: -110/-110

#2 Kentucky vs. #15 Saint Peter’s

Spread: -15.5 Kentucky
Total: 133
ML: -2000/+950

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