MLB Home Run Prop Bet Odds & Picks: Monday (4/21)
Another week of MLB action is in the books, and the New York Yankees tower above all squads with 38 home runs. Of course, the pros in the Bronx are not the only ones showcasing a power stroke early in the campaign.
Here's a look at three players worth backing to launch a ball beyond the fence in today’s best MLB home run bets.
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Monday’s Best MLB Home Run Prop Bets
(Odds courtesy of FanDuel Sportsbook)
Fernando Tatis Jr. (+285)
Fernando Tatis Jr. and his elite production night in and night out is a prime reason for San Diego’s impressive 16-6 record. The young superstar leads the league with a .418 batting average and 1.254 OPS against right-handed pitching. Not only that, but Tatis has racked up the most home runs (eight) of any leadoff hitter. An ability to spray the ball to all parts of the field makes him a threat to go deep anytime he steps to the plate.
A right-hander will face the Padres once more as Detroit’s Keider Montero draws Monday’s start. Take note that Montero was tagged for three homers in his season debut versus the Milwaukee Brewers last Wednesday. It was the fifth time the 24-year-old conceded multiple jacks across 20 career appearances. Tatis has left the yard six times in his previous nine games and has shown no signs of slowing down. Keep riding the momentum.
Pete Alonso (+440)
The long-ball issues that have plagued Philadelphia’s Aaron Nola in the past have followed him into 2025. The right-hander has surrendered four home runs through four starts after being one of six pitchers to allow at least 30 blasts in 2024. Nola travels to Citi Field for a National League East collision with an uninspiring 6.65 ERA and 1.66 WHIP. That’s dangerous, as he will clash with a Mets lineup bolstered by All-Stars.
I’ll focus on Pete Alonso for this bet. After all, he has slashed .327/.386/.731 with a whopping six homers and three doubles in 52 at-bats against Nola. The powerful first baseman also boasts a career-best 61.9% hard-hit percentage and 96.6 miles per hour (MPH) average exit velocity this year. Both rank in the top eight marks among MLB batters. Trust Alonso to continue barreling baseballs in his home stadium.
Marcell Ozuna (+390)
There’s something about playing in front of Atlanta fans that ignites Marcell Ozuna. The Dominican slugger leads the Braves with three home runs and a .719 slugging percentage during the first eight home contests. That is par for the course, considering Ozuna logged a team-high 19 dingers and 55 RBI in home games last summer. Alongside that consistency comes a favorable matchup on Monday evening.
Erick Fedde will be on the mound for St. Louis. The veteran hurler has had several disastrous run-ins with the Braves, posting a dismal 11.08 ERA and 2.25 ERA over 10 outings (40 innings). Those struggles include giving up nine homers in four career starts at Truist Park. The fact Fedde pitches to contact and rarely causes whiffs simply strengthens Ozuna’s case. This wager could cash as early as the opening frame if Ozuna sees a pitch he likes.