MLB Home Run Prop Bet Odds & Picks: Thursday (4/24)
Four weeks of MLB action are in the books. Tyler Soderstrom of the Athletics and Cal Raleigh of the Mariners sit tied atop the home run leaderboard with nine blasts. Of course, they’re not the only ones showcasing a power stroke at the plate.
Let’s take a look at three sluggers worth backing to launch a ball beyond the fence on Thursday, April 24th, with our MLB home run best bets.
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Thursday’s Best MLB Home Run Prop Bets
(Odds courtesy of DraftKings Sportsbook)
James Wood (+450)
James Wood has unleashed his strength. The 22-year-old outfielder checks in among the top 20 MLB players in hard-hit percentage (57.4%) and average exit velocity (94.3 miles per hour). A 431-foot moon shot that came off the bat at 116.3 miles per hour (MPH) in Washington’s win on Wednesday served as Wood’s eighth home run of the campaign. Keep in mind he also boasts a team-high .912 OPS versus left-handed pitching.
As a result, stopping Wood from going deep again is a tough ask of Baltimore starter Cade Povich. The young southpaw has conceded four homers in his last two starts and enters Thursday ranked 347th out of 385 qualified pitchers in hard-hit percentage (50.8%). Povich isn’t forcing whiffs and now travels to the hitter-friendly Nationals Park for the first time. Lock in a wager on Wood before his odds drop any lower.
Bobby Witt Jr. (+400)
Wednesday’s rainout has created a doubleheader between the Rockies and Royals at Kauffman Stadium on Thursday. Bettors have a chance to back Kansas City’s Bobby Witt Jr. in a pair of tantalizing matchups. Just be sure to pay attention as his odds likely won’t be revealed until closer to the first pitch of each game. Witt Jr. sports an impressive .322/.372/.564 slash line with 127 extra-base hits through 245 career home contests.
German Marquez and Chase Dollander are listed as Colorado’s probable pitchers. Marquez has logged a dismal 8.27 ERA across four starts and has surrendered a home run in 19 of his previous 31 outings overall. Meanwhile, Dollander has been tagged for a whopping eight homers in his three starts and is giving up barrels at a rate over 15% higher than the MLB average. Expect Witt Jr. to erupt with a big day swinging the bat.
Bryan Reynolds (+550)
It can be a struggle to find many positives about Pittsburgh’s offense in 2025. However, the consistency of outfielder Bryan Reynolds in his seventh MLB season is a bright spot. The two-time All-Star has found his groove, going 11-for-23 with five RBI in his past five games. Momentum combined with the fact that Reynolds is the lone Pirate with multiple extra-base knocks against left-handed pitching makes him a dark horse to go yard on Thursday.
Veteran southpaw Tyler Anderson will be on the mound for the Angels in this series finale. Anderson has posted a dismal 5.16 ERA and allowed 27 home runs in 32 career starts at Angel Stadium. Take note that Reynolds is 4-for-6 with a dinger versus Anderson and has tallied three homers in seven contests played in Anaheim. Throwing a sprinkle on Reynolds to record two jacks at +5000 odds is an intriguing longshot option here.