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NFL Same Game Parlay Odds, Picks & Predictions (Week 12)

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NFL Week 12 is here, and it’s time to lock in some best bets and props before the games kick-off. The Sunday Week 12 slate isn’t the best, admittedly, but we’re still going to have picks on the games.

Picking matchups against the spread (ATS) and betting on the over/under is more commonplace, but a Same-Game Parlay (SGP) gives us even more added action. Let’s find some plus-money SGP picks for every game on the NFL Week 12 Sunday afternoon slate.

Keep in mind the odds below are accurate as of writing but are always subject to change up until kickoff. Keep track of any of the latest NFL injury news and odds movement before locking in any of these SGP bets. Without further ado, let’s dive into the best NFL Week 12 same-game parlays.

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Best NFL Same Game Parlay Bets (Week 12)

(Odds via DraftKings Sportsbook unless noted otherwise)

Minnesota Vikings at Chicago Bears

The Vikings are on a three-game win streak and now boast an 8-2 record. Meanwhile, the Bears have lost four straight after a promising start to the season. A blocked field goal at the end of regulation cost them the win last week against the Packers. 

Though it's tough for a team to regroup after losing in that fashion - and take on another division rival, no less - let's bank on Chicago giving Minnesota a game this week. With the offensive coordinator change, the Bears offense showed some encouraging signs last week. The game plan called for more quick and easy throws to keep Caleb Williams comfortable under center. Williams was also given more freedom to run and make plays with his legs. 

Chicago scored just 19 points but it also put up 391 total yards while outgaining Green Bay. The offense also went 12-for-19 on third- and fourth-down. The Bears scored on four of its first six offensive possessions before that missed field goal to end the game. We can have more confidence in an offense that's trending up. 

The Bears have a top-10 pass defense, allowing 197.4 pass yards per game (ninth in the NFL) and an 80.2 passer rating (seventh). The secondary also has more interceptions (nine) than passing touchdowns allowed (seven) this year. It's a tough matchup for the Vikings' passing attack and Sam Darnold has regressed over the past month following a hot start. The way to beat the Bears defense is on the ground but the Minnesota run game has been lacking lately. 

This is a prime sell-high and buy-low spot on Minnesota and Chicago, respectively. Five of the Vikings' eight wins this season have come by one score. Meanwhile, the Bears have lost four games by one score. The Bears are also 5-1 ATS and 4-2 straight up (SU) at home compared to 0-3-1 ATS and 0-4 SU on the road. 

Minnesota's defense is allowing league-low 74.4 rush yards per game, which should force the Bears to throw more if they can't get anything going on the ground. The Vikings are also giving up the fifth-most passing yards per game. With that in mind, let's target a pair of props in the Chicago passing attack. 

DJ Moore is coming off his best game in over a month with seven catches for 62 yards last week. The emphasis on Williams making quick, easy throws to his receivers made Moore a clear beneficiary. He should be plenty involved once again. Williams was 23-of-41 (74.2%) through the air last week. He has at least 20 completions in six of his last nine games and the new offensive gameplan should lead to a higher completion rate moving forward. The Vikings are giving up 23.2 completions per game to opposing quarterbacks. 

Parlay Odds: +500

Detroit Lions at Indianapolis Colts

A week after winning a thriller at Houston, the Lions made easy work of the Jaguars in a 52-6 trouncing last week. Detroit is now unsurprisingly a sizable favorite on the road here against Indianapolis. Yet, the Colts have value to cover as home underdogs and make this a game. 

In his return as the Colts' starting quarterback last week, Anthony Richardson had his best game of the season. His 66.7% completion rate and 272 passing yards were both season-highs with a 106.5 QB Rating and two rushing touchdowns. It's only one game but it's still encouraging that the former top draft pick made improvements after being benched. 

Indianapolis still has flaws on defense, but Richardson could have just enough success against an up-and-down Lions secondary to keep things close. The Colts may have six losses this season, but five of them have been by one score. The average point differential in Indy's losses is just 5.3 points per game (PPG). 

Of course, fading Detroit is always a risky proposition but this may be a good spot to do it. There could be a slight letdown/lookahead from the Lions after blowing out Jacksonville last game and with divisional matchups coming up in the next two weeks. They also have a Thanksgiving game on short rest against rival Chicago this upcoming week. Plus, Detroit is averaging 29.6 PPG on the road compared to 37.6 PPG at home. 

The Lions will likely try to get a lead early and then lean on the run game to bleed the clock. The Colts, meanwhile, are allowing 143.1 rush yards per game (28th in NFL). It sets up for both Jahmyr Gibbs and David Montgomery to be productive. Let's roll with Gibbs for this SGP. Besides Week 1, Gibbs is averaging 84 rush yards per game over the past nine contests with at least 63 in each contest. Meanwhile, Indy has allowed at least 60 yards to five straight running backs and seven out of 11 overall this year. 

Though we're backing the Colts, Richardson's inefficiencies as a passer are still there. He has seven interceptions in his six full games this year. The Lions have 14 interceptions in 10 games, tied for the second-most in the league. This defense has also picked off every opposing quarterback this year. A Richardson interception seems likely. 

Parlay Odds: +550 (BetMGM Sportsbook)

New England Patriots at Miami Dolphins

When these AFC East rivals faced off earlier this season, it was a 15-10 win for Miami in a quarterback matchup of Jacoby Brissett vs. Tyler Huntley. That was back in early October, though. The offensive vibes for both teams are much different now. 

The Dolphins’ offense looks much more dangerous with Tua Tagovailoa healthy and back in a groove. Since he returned as the starter, they're averaging 27.8 PPG over the past four games. Last week, Tagovailoa threw for 288 yards and three touchdowns as Miami put up 34 points. The offense is starting to click and that's scary for shaky defenses. 

The Patriots’ defense had shown some improvement recently, but it also benefited from facing the Bears, Titans and Jets over the past month. Against the Rams in their last game, they allowed 402 total yards as Matthew Stafford carved up the secondary. New England has struggled against better attacks and Miami would qualify as that with a healthy Tagovailoa under center. 

On the other side, Miami's defense is trending down right now. It just allowed the woeful Raiders offense to put up 328 total yards last week and has given up at least 325 total yards in four straight games. The Patriots’ offense, meanwhile, has a lot more upside with Drake Maye at quarterback. The Pats are averaging 20.0 PPG in Maye's six starts compared to 12.4 PPG before he took over for Brissett. The rookie signal-caller is getting more comfortable under center and his legs are a real difference-maker. 

Maye is averaging 278.6 combined passing and rushing yards in his five full games this season. The dual-threat ability has been on full display as he beats defenses both ways. He had 282 passing yards alone last week and 95 rushing yards three weeks ago. With Miami's defensive lapses recently and Maye's willingness to make plays with his legs and arm, he can put up numbers here. He has 250+ combined yards in four out of five full starts. 

Tyreek Hill hasn't been nearly as dominant this season as we've seen in the past. Still, he's been mostly productive when Tagovailoa has been healthy. He now has 60+ receiving yards in three of the past four games since Tagovailoa returned. He is averaging 71.8 yards per game in Tagovailoa’s five full games played this year. Hill also has scored in back-to-back games and faces a Patriots defense allowing the seventh-most receiving yards per game to wide receivers. The Pats have also given up 16 pass touchdowns in 11 games.

Parlay Odds: +575

Tampa Bay Buccaneers at New York Giants

It's rare we get a matchup with both teams coming off a bye, but that's the case for the Buccaneers and Giants here. It's also a matchup of two squads stuck in losing streaks entering the bye. Tampa Bay has lost four straight while New York has dropped five consecutive games. 

Since both teams are off their byes, the natural inclination is that this could be a low-scoring game with the defenses well-rested and prepared. The over/under has also dropped notably this week. Even so, this can be a sneaky over bet for a few reasons. 

First off, the Bucs are regularly playing in higher-scoring contests. The over is 7-3 in Tampa's games this year with at least 43 combined points scored in eight out of 10 games. The Buccaneers have allowed 23+ points in six straight games and are giving up 26.6 PPG (27th) and 389.3 total yards per game (30th). 

By now, you've heard the Giants are making the quarterback change to Tommy DeVito. It's surely an interesting move considering Daniel Jones' contract, but that's a conversation for another day. As for DeVito, he could bring a jolt to the Giants’ offense like he did at times last season. Brian Daboll should also have a good game plan for DeVito with the extra week of prep. 

On the other side, Tampa Bay's offense was outperforming expectations before the bye - despite missing Chris Godwin and Mike Evans. Overall, the Bucs are averaging 27.9 PPG (fifth) with at least 20 points scored in all but one game this year. Godwin remains out but Evans has a good chance at returning from his hamstring injury this week. 

Either way, the Buccaneers should have success on the ground against a poor Giants rush defense. The unit is allowing 5.3 yards per carry (32nd) and 147.1 rush yards per game (29th) this year. The Bucs' two-headed backfield of Bucky Irving and Rachaad White can exploit this run defense to take pressure off Baker Mayfield. 

Speaking of Irving, he's separated himself from White when it comes to who is Tampa's best rusher. Irving is averaging 5.1 yards per carry (YPC) with 492 rush yards compared to 3.8 YPC and 306 yards for White. Before the bye, Irving racked up 73 yards on 13 carries. He's also recorded more carries and more yards than White in three straight games coming into this week. The Giants have allowed 100+ rushing yards to three of the past four opposing lead backs they have faced. 

Back to the Giants with DeVito under center. If Daboll is smart, he should have DeVito looking Malik Nabers' way early and often. The rookie wideout has 607 receiving yards in eight games, averaging 75.9 yards per contest. He was a favorite target in the offense with Jones under center and that shouldn't change - even if he doesn't have a rapport with DeVito. This 50+ yards line is low for a guy who's cleared it in seven out of eight games. Meanwhile, the Bucs are allowing the sixth-most receiving yards per game to wide receivers. 

Parlay Odds: +404 (FanDuel Sportsbook)

Dallas Cowboys at Washington Commanders

This is a prime get-right opportunity for Washington after losing back-to-back games to tough Steelers and Eagles teams. Those losses are understandable and the Commanders were leading in the second half of both. Now they're back at home on extended rest (after playing last Thursday) to take on the lowly Cowboys. 

The longer layoff should especially help Jayden Daniels, who hasn't been as good lately while playing through a rib injury. Plus, Washington can regroup between divisional games to get back on track. Banking on a double-digit win is always risky, but these Cowboys vs. Commanders showdowns haven't been close in recent seasons. Each of the past five meetings has been decided by at least two touchdowns and the favorite has covered in five of the past six matchups. 

Dallas, meanwhile, is on a five-game losing streak and coming off a short week after playing on Monday night. The offense has looked lifeless over the past two weeks with Dak Prescott out and Cooper Rush at quarterback. Now, the Cowboys were dealt some key injuries on Monday. Offensive linemen Zack Martin and Tyler Smith along with tight end Jake Ferguson are all questionable. Their potential absences, especially on the offensive line, would downgrade this struggling offense even more. 

Then there's the Dallas defense that's allowed at least 27 points in five straight, giving up 34.4 PPG in this stretch. The Commanders have scored at least 27 points in six of their past nine games, averaging 29.7 PPG since Week 3. Look for the offense to bounce back after being held down last week against Philly. 

The Cowboys have especially struggled to stop the run, allowing 151.0 rush yards per game this year (31st). Brian Robinson Jr. returned as Washington's lead back last week and put up 63 yards and a touchdown on 16 carries against a stout Eagles run defense. He has 60+ rush yards in five of his last six fully healthy games and is averaging 65.5 yards per game (YPG) this season. 

Dallas has allowed at least 60 yards to an opposing rusher in 70% of their games this season. Over the past five games, leading running backs are averaging 85.2 rush yards per game against the defense. The Cowboys have also given up a league-high 18 rush touchdowns over 10 games with at least one allowed in all but two contests. 

In addition to Robinson Jr. having a big day, Austin Ekeler can also be productive in this matchup. He has seen a decent amount of work as both a pass-catcher and rusher in the Washington offense. Ekeler is averaging 67.7 total yards per game with 34.4 receiving and 33.3 rushing per game. He has 50+ combined yards in nine out of 10 contests. The Cowboys have struggled vs. the run but also allow 40.8 receiving yards per game to backs. 

Parlay Odds: +506 (FanDuel Sportsbook)

Kansas City Chiefs at Carolina Panthers

Kansas City's undefeated season came to an end last week with the road loss at Buffalo. The Chiefs should get back on track in an easy matchup against Carolina. They may win, but the point spread is just big enough to take a chance on the Panthers to cover.  

Carolina is coming off its bye week and has quietly won its past two games. Yes, those wins came against the Saints and Giants, but it still shows us that the lowly Panthers aren't just a pushover like they were earlier in the year. On that note, Bryce Young is playing with a bit more confidence since getting his starting job back. 

All of the X's and O's, along with common sense, point to Kansas City winning comfortably here. The spread is also unsurprisingly large because it's the previously undefeated Chiefs facing the woeful Panthers. However, some interesting trends give value to the underdogs in this matchup.

First off, the public perception may be that Kansas City is in prime bounce-back mode after suffering its first loss. Yet, the situational spot is hard to ignore. The Chiefs could just go through the motions in a game it's supposed to win - especially following such an intense rivalry matchup last week vs. Buffalo. Plus, they have divisional games coming up in the next two weeks and could overlook Carolina slightly. 

Kansas City with Patrick Mahomes at quarterback is 0-3-1 ATS as a double-digit road favorite over the years. Mahomes is also just 39% ATS as a double-digit favorite in his career. The Chiefs have been playing close games all season and surviving until it caught up with them last week. Only one of their nine wins has been by 11+ points. Only two of their victories this year are by 10+ points. The Chiefs are also just 1-4 ATS when favored by six or more points this season. 

Now onto some props. Travis Kelce is coming off one of his worst games in recent years with just eight yards on two catches last week. Before that, though, he had at least 64 yards in five of the previous six games. Kelce is still a big part of the Chiefs' passing attack and he'll face a Panthers defense that's allowing 60.8 receiving yards per game to tight ends (seventh-most in NFL). 

Despite the Chiefs being strong against the run, the Panthers have a better rushing attack than you may think. Chuba Hubbard is averaging 5.1 yards per carry and consistently gets 15-20 touches per game (averaging 19.1 touches per game). Yes, the Chiefs are shutting down opposing rushers, but Hubbard has 50+ rush yards in nine straight games while averaging 89.3 yards per game in this stretch. 

Parlay Odds: +415

Tennessee Titans at Houston Texans

The Titans have been one of the most untrustworthy teams against the spread this season. They're now 1-9 ATS, failing to cover in six straight. Tennessee is also just 2-8 straight up this year and impossible to trust to keep games close. Nonetheless, we're banking on that to kick off this SGP. 

Houston just beat Dallas on Monday night with a 34-10 win. Besides the comfortable margin, the Texans barely outgained a Cowboys team that should've scored a couple more times. The blowout win is also uncharacteristic of Houston this season. Of their seven wins, five have been by one score and the Texans have just a +22 point differential overall. 

The Titans have been playing better football lately despite losing to the Chargers and Vikings in the past two games. Both were 10-point losses but Tennessee was within striking distance in the second half each time. Will Levis has looked more comfortable under center since returning from injury this month. The Titans’ defense is also better than you'd think, ranking first in passing yards and second in total yards allowed per game. 

There's also this interesting trend - C.J. Stroud is an impressive 8-4 ATS as an underdog in his career but just 6-10 ATS as a favorite. Even on the road, don't be surprised if Tennessee keeps it within one score. Don't overlook the fact that Houston is coming off an in-state rivalry matchup on short rest as well. 

Though we're backing the Titans, Will Levis' turnovers are hard to ignore. He's thrown an interception in all but one game this season with eight in seven contests. Meanwhile, the Texans have 14 interceptions through 11 games - tied for the second-most in the NFL. The defense has picked off five of their past six opposing quarterbacks, and Levis is likely next. 

Despite that, Levis should find Calvin Ridley enough for the Titans' top wideout to be productive. Ridley has 58, 84, 73 and 143 receiving yards over the past four games since the DeAndre Hopkins trade. The Texans have allowed at least 60 receiving yards to an opposing receiver in all but two games this season. Ridley is that guy for Tennessee. 

Parlay Odds: +435

Denver Broncos at Las Vegas Raiders

After consecutive losses to Baltimore and Kansas City (completely understandable), the Broncos bounced back in a big way last week with a 38-6 beatdown of Atlanta. Sean Payton has his squad playing at a high level right now. The 6-5 record is a bit deceiving because four of those losses are against current playoff teams and the other was back in Week 1 with rookie Bo Nix playing his first NFL game. 

Otherwise, Denver is rolling against easier competition. Five of its six wins this year have been by 14+ points with an average margin of victory of 17.5 points. The Broncos own a +52 point differential and are 8-3 ATS overall, including 4-0 ATS as a favorite. They're rightful favorites of nearly a touchdown on the road and we should bank on them covering. 

Even at home in a divisional matchup, it's hard to get excited at all by Las Vegas. The Raiders are stuck in a six-game losing streak and just lost by 15 to Miami last week. Seven of their eight losses this season have come by seven or more points with an average deficit of 14.4 PPG in their losses. Vegas also has an ugly -98 point differential this season. 

These AFC West foes met back in Week 5 and Denver took home a 34-18 victory in a game it dominated for three out of four quarters. Yes, that was at home and this one is in Vegas, but the Broncos are 5-1 ATS on the road this year. 

Nix is playing efficient football with a ton of confidence right now. He has a completion rate of at least 73% in three of the last four games and boasts a 14:2 touchdown-to-interception ratio since Week 4. He just threw for 307 yards and four scores last week. Nix has at least 215 pass yards in four straight games and in seven out of 11 games this season. Las Vegas has given up 288, 251 and 262 passing yards in the past three games.  

The Raiders continue to struggle offensively, but Brock Bowers is a lone bright spot. The rookie tight end just had 13 catches for 126 yards last week and now has 706 receiving yards this season. He's averaging seven receptions and 70.6 yards per game with 50+ in seven of 10 contests, including five of the past six. Bowers had eight catches for 97 yards vs. Denver earlier this year and should see plenty of targets once again. 

Parlay Odds: +408 (FanDuel Sportsbook)

San Francisco 49ers at Green Bay Packers

It's been a weird season for 49ers fans. After losing at home to Seattle last week, the Super Bowl runners-up from a year ago are now 5-5 with three divisional losses already. San Francisco's playoff hopes are very much up in the air, which makes this game against Green Bay almost a must-win. 

This is the first time the 49ers are underdogs in the regular season since Week 7 of the 2022 season. It's a rare chance to grab them getting points and it's a good time to buy low on a team desperate to get back into the win column. The 49ers are 3-1 ATS after a loss this season and are now 10-4 ATS after a loss over the past three seasons combined. 

The Packers, meanwhile, needed a blocked field goal at the end of regulation to survive against the Bears last week. Green Bay has been fairly lucky in close games thus far with five of its seven victories coming by one score. There could also be some letdown/lookahead potential for the Pack off a hard-fought divisional win and with a Thanksgiving Day matchup on deck. 

Despite the .500 record, San Francisco still boasts a top-10 caliber defense with 302.2 total yards allowed per game (sixth). The Niners have been mostly strong against the pass and can cause issues for Jordan Love and the Packers' air attack. The Green Bay offense has also slowed down a bit lately with 20 and 14 points scored in the past two games. 

San Francisco's offense gets a boost with George Kittle expected back from his hamstring injury after sitting out last week. That means even more with Brock Purdy’s status up in the air as of Friday afternoon. On the other side, the Packers may be without top corner Jaire Alexander as he deals with a knee injury. His absence could loom large for a Green Bay pass defense that will have to handle Kittle, Christian McCaffrey and Deebo Samuel.

The Packers’ defense has decent overall numbers against the run, but the unit is allowing big games to opposing backs. They've given up 70+ yards to a running back in eight out of 10 games this year. Over the past four games, the defense has allowed:

  • 71 yards to D'Andre Swift
  • 138 combined yards to David Montgomery/Jahmyr Gibbs
  • 78 yards to Tank Bigsby
  • 115 yards to Joe Mixon

Last week, Christian McCaffrey ran for 79 yards on 19 carries as his workload increased in his second game back. Bank on another good performance here, especially if Purdy is sidelined or playing injured. 

After Kenneth Walker scored last week, the 49ers have now allowed 13 rushing touchdowns in 11 games. The defense has also given up at least one rushing score in all but two games so far. It's a good spot to bank on Josh Jacobs finding the end zone. The Packers running back has just five scores this season but the trends say he can find pay dirt this week. 

Parlay Odds: +410

Arizona Cardinals at Seattle Seahawks 

All four NFC West teams are within a game of each other in the current standings. Now Seattle (5-5) hosts Arizona (6-4) in a matchup with plenty of playoff implications. The Seahawks just pulled a road upset of San Francisco last week to get back on track. Meanwhile, the Cardinals are coming off their bye amid a four-game winning streak. 

You can make legitimate arguments for both teams to win this game - hence the spread flipping back and forth during the week. Instead, let's focus on the total and root for a high-scoring game. 

The Seahawks are allowing 23.8 PPG (21st) and 349.5 total yards per game (22nd). The defense has especially struggled to stop the run, giving up 138.6 YPG (27th) and 4.8 YPC. That doesn't bode well with Arizona having the fifth-best rushing attack in the league. James Conner has been up-and-down this season but productive in easier matchups with four 100-yard games. Kyler Murray has also been mostly efficient throwing the ball with a 69.2% completion rate and a 12:3 touchdown-to-interception ratio this season. 

On the other side, Arizona's defense is also below average with 346.0 total yards allowed per game (21st). The Cardinals have benefited from playing weaker offenses in recent games (Bears, Jets, Chargers) but previously showed cracks against better teams. Seattle's offense got a boost last week with DK Metcalf back from injury. His return should help Geno Smith get back to better play.

Arizona has also tended to play higher-scoring games on the road compared to at home. Its four road contests thus far have averaged 52.8 combined points. The Cardinals' defense is giving up 29.5 PPG on the road as well. Seattle, meanwhile, is allowing 30.5 PPG over its past four home games.

Let's wrap up this SGP with an offensive-minded prop. Kenneth Walker only had five receiving yards last week but has been a pass-catching weapon out of the backfield. He had at least 24 receiving yards in six straight games beforehand and is averaging 27.8 receiving yards per game this season. The Cardinals are giving up 38.6 receiving yards per contest to opposing running backs and have allowed at least 26 to a back in five straight. 

Parlay Odds: +440

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