NFL Week 12 Anytime Touchdown Scorer Picks & Predictions (2025)
There's no way to sugarcoat it; last week was brutally bad, which is especially disappointing coming off a big Week 10. Much like my first pick, Justin Jefferson, I'm looking to bounce back and have a profitable week. I've got a pretty heavy tight end card this week, mixed in with some players that figure to have massive target shares due to a lack of other options and some players with prices that are auto-bets no matter what the situation is. Here are my NFL Week 12 anytime touchdown scorer picks as we look to get back on track.
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Best NFL Week 12 Anytime Touchdown Scorer Picks
(Odds courtesy of FanDuel Sportsbook)
Minnesota Vikings @ Green Bay Packers
Justin Jefferson (WR – MIN) | +200
I bought low on Justin Jefferson to score at odds of around +175 when he scored at Detroit in Week 9, so I'm absolutely going back to the well on him to score here in Week 12 at longer odds. Despite the disappointing season for his standards, the target share is still absolutely there for Jefferson, who has had nine or more targets in every game since Week 4. He's still one of the best wideouts in the NFL and certainly the top dog in Minnesota, garnering 33% of all Vikings targets inside the 10-yard line and 20% of all red-zone targets.
Jefferson is no stranger to success against division foe Green Bay, scoring five touchdowns in his last seven matchups against Green Bay, including two multi-touchdown performances. Inconsistency at the quarterback position has really made this a frustrating year for Jefferson, but it's giving us some anytime touchdown odds that are simply too good to pass up. This is an auto bet for me any time, so give me Jefferson as one of the best wide receivers in the league to score at 2/1 odds.
Indianapolis Colts @ Kansas City Chiefs
Travis Kelce has certainly bounced back up off the mat after having a really concerning 2024 season, with many questioning whether he should give it a go this season. He currently ranks second in fantasy scoring at the tight end position, and his four touchdowns on the season have already eclipsed his total from last season, just one shy of tying his 2023 mark. The Chiefs like to spread the love offensively, but Kelce still ranks tied for second on the team in terms of red-zone targets (eight) and is third in targets inside the 10-yard line (five).
As good as Kelce has looked this year, though, this play is all about how brutally bad the Colts have been against the tight end position. They have conceded the third-most yards and fourth-most yards fantasy points per game to opposing tight ends, and rank in the bottom 10 in touchdowns allowed to the tight end position. This is my favorite play of the week. Kelce should have a huge day in an advantageous matchup in an absolute must-win spot for Kansas City.
New York Jets @ Baltimore Ravens
Mason Taylor (TE – NYJ) | +320
Jets Rookie tight Mason Taylor only has one touchdown on the season, which, interestingly enough, came in a game where I wrote him up as my best bet when it was looking like Tyrod Taylor would suit up at quarterback. Justin Fields ended up giving it a go, which made me like the play less, but Taylor found paydirt regardless. Taylor is set to start at quarterback this week, which means the Jets’ passing attack should at least have a floor that Fields just isn't capable of maintaining every week.
In Taylor's one start this season, the Jets attempted 36 passes, which is more than they attempted in eight out of nine games started by Fields. That should equate to plenty of targets for Taylor, who is virtually the only real receiving option left standing on this decrepit Jets receiving corps. Taylor leads the Jets in terms of both targets inside the red zone and inside the 10-yard line, garnering 25% and 20% of those looks, respectively. Taylor should look his way around the end zone. The Jets should be chasing points for a majority of this matchup, so I'll take the rookie tight end to log his second touchdown of the season this week.
Seattle Seahawks @ Tennessee Titans
Rashid Shaheed (WR – SEA) | +250
Rashid Shaheed only received one target in his first game with Seattle, but bumped that up to five targets in last week's loss against the Rams, including a target in the end zone that would've been a sure-fire score if Sam Darnold had put just a tad more juice on the ball. Shaheed is currently occupying the role of injured rookie wide receiver Tory Horton, who built a nice early connection with Darnold with five receiving touchdowns on the season. As fast as Horton is, though, it seems Shaheed is just a little bit faster, and I think that connection with Darnold will continue to improve as the pair gets more reps together.
With a career 14.8 yards per reception with receptions of 58+ yards in every year of his career, Shaheed is one of the true deep threats in the league and figures to have several opportunities against this bottom-three Titans scoring defense, which ranks in the bottom seven of fantasy points allowed and in the bottom five of yards allowed to opposing wide receivers. Darnold and Shaheed just missed on a score last week, but I'm betting on them to connect in Week 12.
New England Patriots @ Cincinnati Bengals
It's hard to argue that anyone has a better matchup this week than Patriots tight end Hunter Henry, taking on the league's worst scoring defense in the Bengals, which has been especially bad at defending the tight end position. The Bengals are conceding the most fantasy points to opposing tight ends by a considerable margin, allowing four or more points per game than the next closest team. Their league-leading 12 touchdowns allowed to tight ends is five more than the next closest team.
Henry has been Drake Maye's go-to pass-catcher around the end zone, leading the Patriots with 25% of all red-zone targets and 33% of all targets to Patriots pass-catchers inside the 10-yard line. I expect plenty of points to be scored in this game - with a total sitting just shy of 50 - especially considering the absolute shootouts that Bengals home games have been this season. At +175 odds, I love this play on Henry to find paydirt against the league's worst defense against tight ends.
New York Giants @ Detroit Lions
Brock Wright (TE – DET) | +220
With Sam LaPorta on injured reserve (IR), Brock Wright becomes the de facto No. 1 tight end in Detroit for the foreseeable future. While Wright only had two grabs in that role last week, he saw a season-high seven targets, which is more than double his high in any game previously this season. The game was also played in extremely unfavorable conditions for Lions quarterback Jared Goff, on a very windy and cold night in Philadelphia. Things should come much easier for the Lions this week, back indoors at home against a bottom-five scoring defense in the Giants.
My initial inclination was to play the two-plus touchdowns angle against the Giants with Jahmyr Gibbs, but his odds were hilariously +150 in that market. Scanning the other Lions’ offensive weapons, all are listed at minus odds except for Jameson Williams, whose odds are also way out of range for me. I like the value we're getting with Wright here, and I expect that game in Philadelphia to be an outlier for him, production-wise, as the No. 1 TE in this offense. As long as he's getting a consistent amount of targets weekly, Wright will be a sharp angle in the anytime touchdown market, and I'll go with him to cash that in this week.
Pittsburgh Steelers @ Chicago Bears
Caleb Williams (QB – CHI) | +320
Bears quarterback Caleb Williams is a little bit more mobile than I think most give him credit for, recording at least four carries in all but one of Chicago's games this season with multiple games of 50+ rushing yards and three rushing scores on the season. Williams is tied with running back Kyle Monangai in terms of red-zone carries, and has accounted for 21% of the Bears’ carries inside the 10-yard line and 16% of their carries inside the 5-yard line, which is pretty high considering they have two solid options at running back. The Steelers’ defense is vulnerable to rushing quarterbacks as well, tied for sixth in terms of most rushing touchdowns allowed to opposing quarterbacks.
Williams has also recorded his two biggest rushing games of the season at home, a six-carry, 58-yard performance against Minnesota and an eight-carry, 63-yard outing against the Giants, recording a rushing touchdown in each game. I don't think the odds are reflective of Williams as a scrambler/runner, and I think he'll be more than willing to go get his team a touchdown in a really pivotal game for both teams regarding divisional standings and potential playoff seeding down the line.
Jacksonville Jaguars @ Arizona Cardinals
Michael Wilson (WR – ARI) | +210
Cardinals wide receiver Michael Wilson is coming off an absolutely ridiculous performance, where he recorded 15 receptions on 18 targets for 185 yards in the absence of Marvin Harrison Jr. Yet, he was somehow kept out of the end zone. Jacoby Brissett has absolutely elevated the ceiling and floor of this Cardinals offense, completing an NFL record 47 passes last week and tossing two touchdowns in each of his starts this season.
With Harrison set to miss another game, Wilson should once again split the lion's share of the targets in this offense with Trey McBride, and he figures to have a pretty favorable matchup against a Jaguars defense that is tied for eighth in terms of touchdowns allowed to opposing wide receivers this season. It's pretty absurd that Wilson wasn't able to find the end zone on his historic day, but I'll take him to cash in this week at longer odds than he actually closed at in Week 11.
Cleveland Browns @ Las Vegas Raiders
Michael Mayer (TE – LV) | +380
I'm looking at a Raiders tight end to find paydirt this weekend, but I'm going with No. 2 tight end Michael Mayer to score rather than Brock Bowers, based solely on value. Sharing a tight end room with a player of Bowers’ caliber is certainly not easy, but Mayer has proven to still be a valuable piece on this offense, averaging just shy of three receptions and four targets per game. He has been extremely efficient in the red zone as well, catching 100% of his targets in the red area.
The recent trade of wide receiver Jakobi Meyers also thinned out an already lackluster Raiders receiver corps, leaving Bowers, Mayer and Tre Tucker as the only real receiving options in this Raiders offense. While the Browns’ defense has been pretty formidable at home, here are the point totals that they have surrendered in road games this season: 41, 34, 23, 32 and 27. Add in the fact that Shedeur Sanders is almost guaranteed to gift the Raiders an extra possession or two, and I think the Browns’ defense is in for a very long afternoon. I'll take a shot on Mayer as the Raiders tight end with the longer odds to find the end zone in a game that I think could see a lot of points scored for the home team.
Philadelphia Eagles @ Dallas Cowboys
Jake Ferguson (TE – DAL) | +210
I get that the Eagles’ defense is among the best in the NFL, but these odds are flat-out ridiculous for Jake Ferguson to score this week. It would be hard to argue that anyone in the league is hotter than Ferguson right now, who has recorded seven touchdowns in the Cowboys’ previous seven games. Despite the myriad of options in the Dallas offense, Ferguson ranks fifth in the entire NFL in red-zone targets (15) and is tied for third in terms of targets inside the 10-yard line (nine), garnering 25% and 31% of targets to Cowboys pass-catchers in each respective category.
A total in the high 40s suggests that a fair amount of scoring opportunities should be present in this game, and the Cowboys will likely be chasing points as underdogs of a field goal. I've got no problem backing Ferguson at 2/1 odds or better as the hot hand in Dallas to make it eight scores in his last eight games, even against a pretty stout Eagles defense.
Atlanta Falcons @ New Orleans Saints
Taysom Hill has a pretty solid track record against the Falcons in his career, with seven total touchdowns in the 11 games they've faced off since he really assumed the hybrid quarterback/tight end role in 2019, with three games of multiple touchdowns, including a September matchup last season. While the Falcons’ passing defense was held in pretty high regard throughout the first half of the season, their rushing defense has been a different story, especially after the recent loss of linebacker Divine Deablo.
The Falcons rank in the bottom five in rushing yards allowed and in the bottom six in fantasy points allowed to opposing ball-carriers, and this game actually sets up positively for the Saints’ rushing attack as they enter this game as narrow favorites. We already saw the Falcons get their doors blown off by a bad Miami team without Drake London in a Kirk Cousins start a few weeks ago, and they're in that same situation this week.
Despite his delayed start to the season due to injury, Hill ranks second on the Saints in both red-zone carries and carries inside the 10-yard line, and he's actually responsible for half of all Saints carries inside the 5-yard line. I expect the Saints to control this game and have several goal-line opportunities. I would not be surprised at all to see Hill rack up another couple of scores against a Falcons team that he's had success against throughout his career.