NFL Week 18 Anytime Touchdown Scorer Picks & Predictions (2026)
Soak it in, NFL fans. The last week of the regular season is upon us. Despite the irregularities of the first 17 weeks of the season, we've got some meaningful football to be played across the league to determine the NFC South champion, as well as playoff seeding across both conferences. Implications aside, I'm here to share my best NFL Week 18 anytime touchdown scorer picks for all games taking place on Sunday with available odds. I've only got one play on my card this week with odds shorter than +170, so let's wrap things up in style and have a big end to the 2025 regular season here in Week 18.
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Best NFL Week 18 Anytime Touchdown Scorer Picks
(Odds courtesy of FanDuel Sportsbook)
Atlanta Falcons vs. New Orleans Saints
Both sides appear to be relatively close to full strength in this game, which, hilariously, has huge implications in the NFC South, despite the fact that neither team can win the division. The Saints will be slightly hampered offensively with the absence of Chris Olave. That means increased opportunities for all other Saints offensive personnel, including Swiss Army Knife Taysom Hill.
Hill logged his second-most rushes of the year against the Falcons earlier in the season, toting the rock 10 times, including multiple times right around the goal line, but was denied from reaching the end zone. I find that Hill has been pretty unlucky in the touchdown department overall this season, as he leads all Saints ball-carriers in red-zone rushes and rushes inside the 5-yard line.
Hill has had success in this matchup in previous seasons with seven total rushing and receiving touchdowns against the Falcons in his career, including a couple of multi-touchdown performances. I like him to redeem himself in this matchup and carry one in around the goal line.
Houston Texans vs. Indianapolis Colts
Riley Leonard (QB – IND) | +425
Riley Leonard will get the start under center for the Colts in Week 18, as there's no reason to trot Philip Rivers out there against one of the best defenses in the league in the Texans. While there's obviously not much of a professional sample size to draw from for Leonard here, he did rush for a touchdown against the Jaguars in the only game he played extended snaps in when he came in relief for the injured Daniel Jones.
Leonard was known for his legs throughout his collegiate career, though, racking up 36 rushing scores over the course of four seasons and falling just shy of 1,000 rushing yards in his final season. It's tough to poke holes in anything the Texans have going on defensively, but expect Leonard to get a fair share of carries this week. I'll take a shot on him to use his best attribute and run one in.
New York Giants vs. Dallas Cowboys
Jake Ferguson (TE – DAL) | +225
Cowboys tight end Jake Ferguson may be my most profitable anytime touchdown scorer this season, especially coming off a Christmas Day game where he came through as my best bet for both a first touchdown and anytime touchdown. Ferguson has been a monster in the scoring area this season, leading the Cowboys and ranking fifth in the entire NFL in red-zone targets and targets inside the 10-yard line.
Ferguson was held scoreless but still had a big day against the Giants when these two teams first matched up this season, reeling in nine receptions on 12 targets for 78 yards. Part of the reason that Ferguson has been so profitable is that he's almost always somewhat overlooked, sitting around 2/1 odds or better because of the array of weapons on the Dallas offense - even when he ripped off six touchdowns in a four-game span in the middle of the season.
I'll look to capitalize on that oversight one last time this week, in a matchup between two teams that scored a combined 77 points in Week 2.
Cincinnati Bengals vs. Cleveland Browns
Tee Higgins provided immediate returns on his contract extension, staying mostly healthy and hauling in 10 touchdown receptions this season. Higgins saw plenty of high-leverage targets this year, ranking right behind Ja'Marr Chase in red-zone targets and targets inside the 10-yard line on the Bengals.
While the Browns’ defense is regarded as one of the best units in the NFL, their numbers drop off a cliff when they go on the road. Here are the point totals and associated opponents in Browns road games this season:
- 41 (Ravens)
- 34 (Lions)
- 23 (Steelers)
- 32 (Patriots)
- 27 (Jets)
- 10 (Raiders)
- 31 (Bears)
The Bengals certainly have the offensive firepower to rank in the upper echelon of that group of teams, and I expect them to have plenty of scoring opportunities on their home turf. Chase broke his scoreless streak with two touchdowns last week, and I think it's Higgins' turn to get back in the scoring column this week.
Jacksonville Jaguars vs. Tennessee Titans
Bhayshul Tuten (RB – JAX) | +280
Rookie running back Bhayshul Tuten had a pretty successful rookie campaign, running former No. 2 RB Tank Bigsby out of town and assuming the role for himself. Tuten carved out a nice role for himself around the scoring area despite sharing the workload with Travis Etienne and Trevor Lawrence, garnering just under a quarter of the Jaguars’ carries inside the red zone and inside the 5-yard line.
I've picked on the Tennessee rushing defense all season long, as the 16 rushing touchdowns they have allowed rank tied for the third-most in the NFL. Tuten was responsible for one of those scores against the Titans just a few weeks ago. The Jaguars are the biggest favorites on the board this Sunday, favored by nearly two touchdowns. Etienne and some of the other starters may get some rest in the latter portion of this game once it's clear the Jaguars have the game and division locked up. That would mean even more attempts for Tuten. I love him to score at this price.
Los Angeles Rams vs. Arizona Cardinals
Colby Parkinson (TE – LAR) | +250
Rams tight end Colby Parkinson has been held scoreless for two consecutive weeks after emerging as one of Matthew Stafford's favorite targets down the stretch. He ripped off six touchdowns in the six games prior. Parkinson trails only Davante Adams on the team in red-zone targets and targets inside the 10-yard line, outpacing even Offensive Player of the Year candidate Puka Nacua.
The Cardinals’ defense has had issues defending the tight end position all season long, ranking in the bottom seven or worse in fantasy points allowed, receiving yards allowed and touchdowns allowed to opposing tight ends. Parkinson was responsible for one of those scores himself against the Cardinals four weeks ago. With Terrance Ferguson scoring in consecutive weeks, I think this is a good time and price to buy back on Parkinson to get into the end zone in a solid matchup.
Denver Broncos vs. Los Angeles Chargers
Troy Franklin (WR – DEN) | +230
I believe second-year receiver Troy Franklin has been a little bit unlucky in the touchdown department, considering his volume of high-leverage targets. Franklin and Bo Nix have brought their college connection to the NFL, as Franklin leads all Broncos receivers in red-zone targets and targets inside the 10-yard line.
While the Chargers’ defense was regarded as one of the best in the NFL for a majority of the season, we saw them get absolutely eviscerated in the early goings of last Saturday's game against a Texans offense that sometimes finds itself stuck in the mud, allowing a 75-yard touchdown and a 43-yard touchdown on back-to-back possessions. With Justin Herbert set to rest this week, there should be ample offensive opportunities for the Broncos to score, who still have an incentive to play for this week with the No. 1 seed in the AFC at stake.
Perhaps the Broncos take a page out of the Texans’ playbook, using Courtland Sutton as a decoy, giving Franklin a better opportunity to score. Franklin and Sutton's anytime touchdown scorer odds were mirroring each other for a good percentage of the season, so I'll buy low on Franklin to get back into the end zone this week.
New England Patriots vs. Miami Dolphins
Jaylen Waddle (WR – MIA) | +200
Dolphins wide receiver Jaylen Waddle has put together a really solid 2025 season in the midst of all the turmoil in the organization, with 910 receiving yards and six touchdowns on 64 receptions. He leads all Dolphins pass-catchers in red-zone targets, and is tied for second on the team with De'Von Achance in targets inside the 10-yard line. The Patriots are much more susceptible through the air than they are on the ground, and the 16 touchdowns they have allowed to opposing wideouts are tied for the ninth-most in the NFL.
Waddle was the recipient of one of those touchdowns in a Week 2 matchup between these squads that saw 60 total points put up on the board. I still don't know exactly what to think about Quinn Ewers as an NFL quarterback, but he at least showed some competency last week with two scores against a pretty solid Buccaneers defense. Give me Waddle to cap off his season with another touchdown against the Patriots.
Chicago Bears vs. Detroit Lions
Amon-Ra St. Brown (WR – DET) | +120
Amon-Ra St. Brown is undoubtedly my favorite play on the card this week, with an A+ matchup against a Bears defense that has been horrific at defending opposing wideouts this year. The Bears are allowing the third-most fantasy points per game to receivers, and the 20 touchdowns they have conceded are tied for the second-most allowed in the NFL.
St. Brown himself is responsible for three of those touchdowns, as he lit the Bears up for 115 yards on nine receptions when these teams squared off in Week 2. St. Brown is the clear go-to target around the end zone in this offense, leading the entire NFL in red-zone target share (41.3%) and target share inside the 10-yard line (50%).
This game features the highest total on the board in Week 18, evident by the fact that they combined for 73 points in the aforementioned Week 2 matchup, so I expect plenty of possessions and points from both teams. I would be shocked if the Bears keep St. Brown out of the end zone this week, and I'll be sprinkling on him to have a multi-touchdown performance as well.
Buffalo Bills vs. New York Jets
Khalil Shakir (WR – BUF) | +260
Khalil Shakir is in the midst of a pretty significant touchdown drought, going scoreless in the previous three games with only one touchdown in the previous nine games. It hasn't necessarily been because of a lack of opportunities, though, as Shakir somewhat surprisingly leads all Bills pass-catchers in red-zone opportunities (23%).
The Jets’ defense hasn't been able to stop a nosebleed all season long, almost surpassing the Bengals and Cowboys for the worst scoring defense in the NFL. The Bills had no problems scoring on them in Week 2, hanging 30 points in a dominant victory. I don't necessarily think a blowout kills Shakir's chances to score this week either, as I cashed on Stefon Diggs last week despite the Patriots’ 32-point blowout win against the Jets.
I find these odds to be too long for Shakir, given his target share and red-zone opportunities. I like this price on him to get back into the scoring column against a Jets defense that seemingly allows 30+ points every week.