NFL Week 2 Anytime TD Scorer Picks & Predictions (2025)
Week 1 was good to us, seeing multiple guys get in the end zone around or above 2/1 odds in George Kittle, Zach Ertz and Daniel Jones, as well as my favorite bet of the week cashing with Brian Thomas Jr. With Week 2's slate, I'm providing a variety of anytime TD options, ranging from stud WRs who just didn't find paydirt in the opener to high volume value targets on overlooked offenses and a few rookies looking to get in the end zone for their first career touchdown. With one week of games and data under our belt, here are my best bets for anytime TD scorers in Week 2 of the NFL season.
Get instant alerts when a line reaches your target via the BettingPros App >>
Best NFL Week 1 Anytime TD Scorer Picks
(Odds courtesy of FanDuel Sportsbook)
Los Angeles Rams @ Tennessee Titans
The Rams were able to overcome the offseason speculation that QB Matt Stafford might not be entering this season healthy, collecting a 14-9 victory over a 2024 playoff team in the Texans. Despite leaving the game multiple times due to a bloody forehead and necessary concussion protocols, WR Puka Nacua racked up 10 catches on 11 targets for 130 yards, which was far more efficient than Davante Adams' four receptions on eight targets. The only other Rams pass catcher to catch more than one ball was TE Colby Parkinson, who actually recorded -6 yards on his two receptions. Things figure to come a little bit easier for the Rams offense this week as well, as they'll be taking on a much worse Tennessee Titans team compared to Houston's top-6 passing defense. With Nacua and Adams having nearly identical odds to score this week, I've got to go with the guy that outperformed in terms of both volume and efficiency in Week 1. Give me Nacua to find the end zone for his first TD this season.
Jacksonville Jaguars @ Cincinnati Bengals
Bhayshul Tuten (RB – JAX) | +250
Rookie RB Bhayshul Tuten is by far the biggest beneficiary of this week's Tank Bigsby trade, as Tuten is now the definitive #2 RB for the Jaguars behind Travis Etienne Jr. Tuten had a ton of hype surrounding him in the offseason with many envisioning that he would take on the Bucky Irving role in the Liam Coen offense, and the trade of Bigsby certainly proves that the Jaguars value him highly. While he only got three carries in the opener, he should absorb the five carries that went to Bigsby and I don't necessarily think the Jags will be doling out 4+ rushes to receivers every week, so I predict Tuten getting close to 10+ touches on a weekly basis going forward. While the Bengals defense did offer some resistance in Week 1, the Jaguars offense looked to be much more explosive than the Browns, and it's going to take more than one solid defensive performance for this Bengals defense to prove that they are more competent than last year's version. I'll buy into the Tuten hype and take him to get his first career NFL TD in Week 2.
Cleveland Browns @ Baltimore Ravens
Harold Fannin Jr. (TE – CLE) | +380
If you weren't paying close attention last Sunday, you probably missed that Browns rookie TE Harold Fannin Jr. had a fantastic debut, catching seven balls on a team-leading nine targets for 63 total yards. This is nothing new for Fannin, who broke the FBS record for TE receiving yards (1,555) and TE receptions (117) in a single season while at Bowling Green. While this might look like a poor matchup for Fannin on paper, the Ravens are fresh off surrendering 41 points in a game which they allowed Buffalo TEs to combine for 60 yards on 6 catches and a TD. In fact, a trailing game script benefits this play by forcing the Browns to attack through the air more often, which they may need to do anyway after rushing the ball for only 49 yards on 24 carries against one of 2024's worst defenses in the Bengals. It looks like Joe Flacco has already established a connection and trust with Fannin, and I don't think we continue to see his odds this long for the remainder of the season. As long as Flacco remains under center, I like Fannin's high target volume to continue, and I love these odds for him to find paydirt this Sunday.
Buffalo Bills @ New York Jets
Khalil Shakir (WR – BUF) | +220
As dynamite as the Bills offense can be, their pass catching personnel makes it tough to predict who might find the end zone on any given week. I'm looking toward WR Khalil Shakir in Week 2, who ranked second behind Keon Coleman in terms of targets, yards and receptions for Buffalo this past Sunday. Shakir's matchup against the Jets is looking more favorable than it did before the season, as the Jets just got torched by a Steelers offense that has been offensively inept in recent years led by a 41-year old Aaron Rodgers. I find it likely that Coleman will draw most of the assignments from Jets top CB Sauce Gardner as the bigger-bodied X-receiver, with Shakir operating primarily out of the slot in a role similar to Steelers WR Calvin Austin last week, who reeled in four catches for 70 yards and a TD against the Jets. The Jets opening week offensive performance combined with the Bills' horrendous defensive showing indicates that we might have a high-scoring affair on our hands in this game, and this rendition of the Jets might be able to keep pace with the Bills compared to their previous iterations. In that case, the Bills will need to keep putting points on the board, and I like Shakir to be the beneficiary of a TD this week.
New England Patriots @ Miami Dolphins
Kayshon Boutte (WR – NE) | +290
Despite the offseason acquisition of Stefon Diggs, WR Kayshon Boutte paced the Patriots pass catchers in terms of targets (8), receptions (6), yards (103) and YPC (17.3) in their season opener. While it's easy to overreact to Week 1 results, Boutte and the Patriots seemingly have an A+ matchup against a Dolphins defense that just had Daniel Jones looking like one of the top QBs in the league. Boutte profiles very similarly to Colts WR Michael Pittman Jr., who reeled in six catches for 80 yards and a TD against the Dolphins, and I can see him having identical success this week. While I do think the Patriots will have some goal line opportunities against Miami on Sunday, their RB situation is too murky for me to confidently pick one to score, and we could always see Drake Maye run it in himself like Jones did twice last week. Instead, I'll take these juicy odds on what might just be the Patriots top pass-catching option in Boutte to score a TD against a Dolphins defense that couldn't stop a nosebleed in Week 1.
San Francisco 49ers @ New Orleans Saints
Juwan Johnson (TE – NO) | +400
Saints TE Juwan Johnson was the top dog in terms pass catchers for the Saints in Week 1, recording eight receptions on 11 targets for 76 yards. That figures to be a sign of things to come in a depleted Saints WR room, as Chris Olave and Rashid Shaheed were the only other receivers to record more than three receptions. While the 49ers defense was certainly stout in Week 1, they faced a Seattle offense led by Sam Darnold, who seemingly turned back into a pumpkin after leaving Kevin O'Connell. Additionally, the injuries to Brock Purdy and George Kittle make this game much more winnable for the Saints than it originally seemed. Fortunately for us, the perception of the Saints' offense as a whole is still providing great odds for Johnson to score this week. As long as he's receiving this kind of volume from whoever the Saints trot out at QB, Johnson is a great anytime TD value play as a big-bodied TE around the red zone going forward.
New York Giants @ Dallas Cowboys
Cowboys WR CeeDee Lamb comes in as my shortest odds anytime TD play of the week, and for good reason. Lamb doubled up the next closest Cowboy pass catcher in terms of both targets and receptions, and recorded 80 more yards than the next closest receiver George Pickens. That was all in spite of his inability to come up with a few more monster catch opportunities that would have put him well on his way to 200+ yards and a likely TD. Although the Giants "only" gave up 21 points last week, they surrendered 430+ yards of total offense and allowed an aging Deebo Samuel to bring in seven catches for 77 yards while scoring a TD (albeit it came on his lone rush attempt, which Lamb will also periodically do). Dallas had success moving the ball in Week 1 and left some points on the field against one of the best defenses in the NFL, so I don't think they'll have any problem putting up a big number against the Giants in their home opener this Sunday. Look for Lamb to be involved early and often and find the end zone this week, and I don't hate looking at escalators for multiple TDs either.
Chicago Bears @ Detroit Lions
Colston Loveland (TE – CHI) | +480
The Bears offense looked absolutely electric on Monday Night under first year Head Coach Ben Johnson...for the opening drive, and then we were all forced to watch the horror show that has been the Bears' offense for the greater part of their franchise's history. Despite their late-game collapse, I find reason to believe Chicago's offense will look much improved this week compared to their opener. For starters, nobody should know how to attack this Lions' defense better than their Head Coach Ben Johnson, who served as Detroit's OC from 2022-2024 when their offense ranked among the best in the NFL. The Bears should also be facing an easier defensive matchup against the Lions this week than the ultra-aggressive defense of Vikings DC Brian Flores, and they will have shaken off the first game jitters and have one game under their belt in the new offensive system. Additionally, I don't think it's a stretch to believe that Ben Johnson held some things back in the opener to pull out of the bag this week in his return to Detroit. Regarding Colston Loveland specifically, the Bears drafted him 10th overall for a reason, and I like him to fill the same role that Green Bay TE Tucker Kraft did when he found the end zone against Detroit last week. Both Chicago TEs have nearly identical odds this week, so take whichever you prefer (or split the wager and take both), but my money is backing Loveland to score his first career TD in Week 2.
Seattle Seahawks @ Pittsburgh Steelers
Zach Charbonnet (RB – SEA) | +210
Seahawks RB Zach Charbonnet was one of the lone bright spots for the Seattle offense in Week 1, recording the team's only touchdown and racking up 2 more carries than Kenneth Walker III at nearly double the YPC. While usually you would want to avoid backing offensive production against a Mike Tomlin-led defense, the Steelers are fresh off surrendering 182 rushing yards at nearly 5.0 YPC to a Jets offense that has been pretty putrid for quite some time. While Sam Darnold doesn't quite offer the same mobility as Jets QB Justin Fields, Breece Hall still racked up 100+ yards of his own at 5.6 YPC, and we saw Jets backup RB Braelon Allen find the end zone on a goal line carry. I like Charbonnet to find the end zone again in Week 2, whether it be from a goal line carry or a long run that he's able to break off. In a Seattle backfield that seems split nearly 50/50 after Week 1, I'll take the guy with the longer odds against a Pittsburgh defense that was gashed on the ground in Week 1.
Denver Broncos @ Indianapolis Colts
Tyler Warren (TE – IND) | +260
Colts rookie TE Tyler Warren was somewhat overlooked in their opening week domination of the Dolphins, as he was able to bring in seven receptions on a team-leading nine targets for 76 yards. Though the Broncos still figure to have one of the league's best defenses in 2025, Warren should be able to operate in the middle of the field away from reigning DPOY CB Patrick Surtain. Much like Colston Loveland with the Bears, the Colts invested heavily in Tyler Warren with the 14th overall pick in this year's draft, and I predict that they will continue to feed him touches in any way possible. His skill set pairs well with Daniel Jones in the short passing game and it seems like a trust has already been established in his young career, therefore I like for them to convert that into a TD in what should be a really fun matchup against the Broncos this week.
Carolina Panthers @ Arizona Cardinals
It's tough to find a value anytime TD play in a game that figures to have little defensive resistance, but I think I might have one here with Carolina QB Bryce Young. One of Young's best attributes as a young QB is his ability to take off and scramble when he doesn't have a throwing option, as evident by his 40 yards on just five carries last week. Young had his biggest rushing performance of the 2024 season against this same Cardinals defense, where he totaled 68 yards on five carries for 13.6 YPC and a TD. I don't think either of these teams have changed all that much since last year, and Young might even be a little more eager to abandon the pocket this week after tossing two INTs in the opener against a Jacksonville defense that struggled mightily in 2024. I was shocked to see Young's odds this high in Week 2, and I'll take him to have a repeat performance against the Cardinals and find the end zone against them again this week.
Philadelphia Eagles @ Kansas City Chiefs
Patrick Mahomes (QB – KC) | +370
The Chiefs find themselves in a precarious spot in Week 2, taking on the defending champions after dropping their Week 1 matchup in Brazil to the division rival Chargers. They'll also be missing multiple offensive weapons in this matchup with the Eagles, due to the preseason suspension of WR Rashee Rice and Week 1 injury to WR Xavier Worthy. QB Patrick Mahomes took it upon himself to carry the Kansas City rushing attack in their opener, as he led the team with six carries for 57 yards and a TD. With the aging TE Travis Kelce remaining as the only real red zone threat remaining and the Chiefs' backs pressed up against the wall to pick up a huge Week 2 win, I like Mahomes to do whatever it takes to find the end zone. I don't think his odds are reflective of the Chiefs' situation entering Week 2, and I'll take him as my best anytime TD bet in what might be the game of the week this Sunday.