NFL Week 2 Same Game Parlay Picks & Predictions: Seahawks vs. 49ers (2022)

Check out our top same game parlay odds, picks, and predictions for the NFL Week 2 contest: Seahawks vs. 49ers.

All odds courtesy of DraftKings Sportsbook 

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NFL Week 2 Same Game Parlay Picks & Predictions: Seahawks vs. 49ers

Seattle Seahawks at San Francisco 49ers -8.5, Total 41

  • Leg 1: Trey Lance over 38.5 rushing yards
  • Leg 2: Trey Lance anytime TD scorer
  • Leg 3: 49ers -8.5

Odds: +834

As you can probably tell, I’m not taking a ton of stock into what we saw from both of these teams last week. The 49ers played in frankly unplayable conditions, and not even Tom Brady could’ve played well in those elements. I think the 49ers will unleash Lance against a Seahawks defense that struggled mightily against Denver last Monday night, allowing 433 yards and 5.2 yards per rush. And after a strong first half from Geno Smith, the Seahawks’ offense looked more like the inept unit we expected in the second half. It’s rare to get a buy-low spot on a team laying over a touchdown, but I think that could be the case in this one.


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