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NFL Week 6 Early Odds & Predictions: Bills vs. Chiefs (2022)

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In Week 5, the top-scoring offense in football was shut out, the Jets put up 40 against the Dolphins and the winless Texans managed to knock off the Jaguars in Jacksonville. The Giants also managed to mount a two-score comeback against the Packers in London to move to 4-1 on the season.

Week 6 features some very lopsided matchups and a meeting between the Bills and Chiefs in Kansas City. Where can you expect the lines to move as kickoffs approach? Let’s take a look at Bills vs. Chiefs.

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NFL Week 6 Early Odds & Predictions: Bills vs. Chiefs

Buffalo Bills at Kansas City Chiefs

A potential preview of the AFC Championship game features two quarterbacks putting up outstanding numbers. Josh Allen decimated the Steelers in Week 5, throwing for 424 yards and four touchdowns.

The performance has made the Bills an early favorite, despite this game being played in Kansas City. While the Bills are likely the better team, it’s hard to imagine the line moving in their favor when Patrick Mahomes is playing at home. 

Look for bettors to back the Chiefs, as this line will become negligible prior to kickoff, ultimately ending as a pick ‘em.

Current Line: Bills -2

Predicted Final Line: Pick ‘em

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Phil Wood is a featured writer at BettingPros. For more from Phil, check out his archive and follow him @Phil_Wood_Jr.