Seahawks vs. 49ers: NFL Week 14 Odds & Picks (2023)

Gear up for another weekend of NFL action! Make sure to check in with BettingPros throughout the year for top picks and predictions for each and every NFL game. Our writers dive into their favorite picks and predictions for every remaining game on this weekend’s NFL slate. And let’s take a closer look at Seahawks vs. 49ers.

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NFL Odds, Picks & Predictions: Seahawks vs. 49ers

Seahawks vs. 49ers

On Thanksgiving, the 49ers earned a 31-13 win over the Seahawks on the road. Now they’ll be home for this matchup. It’s unlikely we get a different result. Brock Purdy is in the MVP conversation and only had a three-game stretch before the bye week where he struggled. He might’ve been dealing with a concussion at that time. He’s super accurate and has a ton of playmakers around him. In some games, it’s Christian McCaffrey. In other games, it’s Deebo Samuel. Brandon Aiyuk and George Kittle have also had some massive games. Any week a couple of these guys step up and make big plays offensively. Meanwhile, Geno Smith and the Seahawks have taken a step backward this season offensively. Finally, when the offense figured it out last week, the Seahawks’ defense allowed 41 points in a 41-35 loss. Seattle has lost four of its last five games. They’ll take another loss here and fall below .500. Back the 49ers against the spread at -11.

Pick: 49ers -11

-Jason Radowitz


What is Betting Against the Spread?

Betting “against the spread” refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.


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