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Thanksgiving Day Football Odds, Picks & Predictions: Bills vs. Lions (Week 12)

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With week 11 of the 2022-23 NFL regular season now in the rearview, the attention now turns to Thanksgiving Day as six teams will be in action. Starting with the Turkey Day mainstay Lions hosting the Bills, the Giants visit Dallas before the day is rounded out with New England in Minnesota.

Here’s a look at all three games and where the value is ahead of opening kickoffs. And let’s dive into the matchup Bills vs. Lions.

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Thanksgiving Day Football Odds, Picks & Predictions: Bills vs. Lions

Buffalo Bills vs. Detroit Lions, 12:30 PM EST

  • Opening Line: Bills +9 | O/U 52.5
  • Current Line: Bills +9.5 | O/U 53.5
  • Last meeting: December 16, 2018 – Lions 13, Bills 14

Analysis:
In the Bills’ 31-23 win over Cleveland last week (in Detroit), the Browns were limited to 3.1 yards per rush by the Buffalo defense, as the Bills’ defense stepped up following three games in which opponents had averaged 5.9 YPC.

The Lions won 31-18 over the New York Giants last week, recording their third straight victory as an underdog. The Giants, who were 3-point favorites, outgained Detroit 413 to 325 yards, but they were defeated by a turnover differential of -3.

At three games now, the Lions’ winning streak is the franchises’ longest since 2017. Look for that confidence to come through in this one as they keep it close.

Pick: Lions +9.5

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