UConn vs. USC Women’s NCAA Tournament Predictions (Elite Eight)

The second half of the NCAAW Elite Eight will see TCU vs. Texas at 7 p.m. EST, followed by UConn vs. USC at 9 p.m. EST. With the talent playing in both matchups, fans are in for some great games, and of course, several wagers for our 'NCAAW Elite Eight Best Bets' list. These are not the only outstanding wagers. But they are the ones we feel belong on our 'Best Bets' list (odds via DraftKings). Here are our top picks and predictions for UConn vs. USC.

2025 NCAA Tournament March Madness Bracket Strategy & Betting Picks>>

Best Women’s NCAA Tournament Elite Eight Bets: UConn vs. USC

(Odds courtesy of DraftKings Sportsbook)

 

No. 2 UConn Huskies (-13.5) vs. No. 1 USC Trojans (+800)

  • Time: 9:00 p.m. EST
  • Coverage: ESPN

This is a game fans were looking forward to when the bracket was announced. A little of the shine has come off the game with JuJu Watkins out after injuring her knee. But the Trojans have managed without her, destroying Mississippi State 96-59 and handling Kansas State 67-61.

What is most impressive is how they did it. Against the Bulldogs, USC's other star, Kiki Iriafen, stepped up with 36 points and nine boards. But against a tougher Wildcats team, it was more of a team effort, with three players other than Iriafen scoring double digits.  But facing a team like UConn without Watkins is something else entirely.

The Huskies have been one of the best teams in the country all season. They have the No. 1 defense in the country (51.5 ppg allowed) and a top ten offense that averages 80+ points per game. Paige Bueckers may not have played well enough to win the Wooden Award this season. However, she is still widely regarded as one of the best players in the country.

It's a big spread for a game between two really good teams. But it is one thing to overcome the odds to beat a K-State squad and something else entirely to do it against a team like the Huskies. USC will make a game of it, but the Huskies will pull away in the second and cover the spread.

Pick: UConn -13.5 (-110)


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