College Football Parlay Picks for Week 13 (2021)

The final week of the college football season is upon us which means that there will be rivalries renewed all across the country. It doesn’t get any better than Week 13 from both an entertainment and college football betting perspective. While there are plenty of games worthy of individual wagers and attention, parlaying multiple picks into one ticket offers bettors a chance at an even more rewarding payout.

The following article outlines two featured college football parlay picks for Week 13. Additional wagers are included at the end of the column as well for those who wish to mix and match beyond the pre-constructed parlay bets.

Bet online at BetMGM with special offers >>

All odds taken from BetMGM Sportsbook

Week 13 Featured College Football Parlay #1

Our first featured parlay ticket for Week 13 focuses on the first half of Saturday’s loaded college football slate. This five-leg parlay hones in on various moneyline favorites along with a preferred bet ATS. The ticket carries +198 odds as a result of the combined wagers. 

Indiana at Purdue (-750)

After getting throttled by mighty Ohio State, Purdue calmly got back on track last weekend with a comfortable road win over Northwestern. Now, they get to finish off the regular season with the annual battle for the Old Oaken Bucket. This will be the 123rd all-time meeting between Indiana and Purdue, and this year, the Boilermakers figure to have a decisive edge.

The Aiden O’Connell to David Bell connection continued to roll last week. Fellow wideout Milton Wright also got in on the fun with a 200-yard game. Good luck to a banged-up Indiana team with slowing down Purdue’s aerial assault.

Georgia Southern at Appalachian State (-2500)

This Sun Belt Conference tilt sees 9-2 Appalachian State host 3-8 Georgia Southern on senior day in Boone. The records of these two teams speak for themselves. The Mountaineers are looking to finish off an undefeated season at home and lock themselves into next weekend’s conference championship game.

Miami (-1600) at Duke

For all of the criticism of Manny Diaz and speculation regarding his future as the head coach at Miami, the Hurricanes have finished out the season playing hard. Miami will go bowling this postseason and aims to cap off a seven-win season on Saturday. To do so, they’ll just need to beat a Duke team whose defense ranks dead last by a mile in the ACC in yards (516.9) and points (39.1) allowed per game. In fact, the Blue Devils’ scoring defense is one of the worst in the entire FBS, ranking 125th in points allowed per contest. Containing a competent offense like Miami’s is next to impossible for this Duke outfit.

Hawaii at Wyoming (-400)

Wyoming went into last Saturday’s road game in Logan, Utah, sitting dead last in the Mountain West Mountain Division. After putting a hurting on Utah State, the Cowboys will now aim to boost their bowl hopes against a Hawaii program in need of a sixth win to become bowl eligible. This is actually considered a rivalry game, complete with the Paniolo Trophy to boot.

While the Rainbow Warriors got there for us at home last week, they are yet to win a conference game on the road all season. A trek to Laramie doesn’t figure to end well for a team with one of the largest home-road margins in the country.

Florida State (+3) at Florida

We wrap up this first college football betting parlay by taking Florida State catching a full field goal on the road in the annual Sunshine State rivalry game against Florida. A loss to North Carolina State back in the first week of November dropped the Seminoles to 3-6 on the season. Yet, here they are three weeks later, just one win away from playing their way into the postseason. While Mike Norvell has his squad fighting hard for bowl eligibility, the entire Gators program is in turmoil. 

Florida has not beaten an FBS opponent since September and just fired head coach Dan Mullen after last week’s loss to South Carolina. The Gators look like a team whose season can’t end soon enough. FSU should keep this one competitive right down to the wire at a minimum. A sprinkle on the moneyline is also a worthwhile play.

Parlay Ticket: +198

Week 13 Featured College Football Parlay #2

Our second featured college football betting parlay for rivalry week is a three-leg ticket that focuses on the latter portion of Saturday’s slate. Although smaller than the first parlay laid out above, the fact that all three picks come against the spread results in a greater level of difficulty and a larger potential payout at +595 odds.

Oregon State (+7) at Oregon

The annual Civil War rivalry game has heightened stakes this year with both teams potentially in line for a berth in the Pac-12 Championship game. The visiting Beavers certainly come in with more momentum after winning their last two games including an outright upset of Arizona State last weekend. Following a horrendous effort against Utah that saw their College Football Playoff hopes disintegrate, how will Oregon respond? 

With the Pac-12 now having no shot of getting a team into the playoff, a conference title is necessary to play in the Rose Bowl. The Ducks are the more talented team, but the gap between these two programs is not a full touchdown. Expect the Beavs to keep this one close given what is on the line.

Kentucky (+3) at Louisville

The last time Louisville faced an SEC team was all the way back in Week 1. They got trounced by 20 points on a neutral field to Ole Miss. While back-to-back blowouts of Syracuse and Duke coming into Saturday night’s battle for the Governor’s Cup are nice, they shouldn’t change Louisville’s power rating any. Kentucky slumped down the stretch of the SEC schedule before cruising past Vanderbilt and New Mexico State each of the last two weeks. 

While Mark Stoops’ defense should be able to make life frustrating for Malik Cunningham, it’s hard to envision the Cardinals’ D truly stopping Will Levis and the Wildcats. The SEC has been a much better league than the ACC all season. Expect that sentiment to hold form in this Bluegrass State rivalry.

BYU (-7) at USC

We successfully faded USC against in-city rival UCLA last weekend and will go right back to the well in Week 13. BYU still has an outside chance of earning a New Year’s Six bowl bid if they can knock off the Trojans in impressive fashion and have some other things shake out in their favor.

USC has been awful at home all season and is a team that just wants this season to be over with. Getting hyped up to stop the freight train that is Tyler Allgeier and the Cougars ground game is not something USC’s defense figures to be overly excited about doing.

Parlay Ticket: +595

Other Week 13 College Football Bets to Consider

While the three featured parlays above have been constructed for you, the beauty is that bettors can mix and match to build their own parlays as they wish. Not feeling convinced by any of the picks above? Looking to build an even bigger parlay? This section is for you! Below are a few additional college football bets to consider for Week 13. Good luck with all of your NCAAF wagers this week and enjoy the games!

Moneyline Favorites of Various Degrees 

Ohio State (-300)
Navy (-550)
Alabama (-1400)
Arizona State (-1100)
Oklahoma State (-200)

Moneyline Underdogs with Bite 

Florida State (+120)
Tulsa (+185)
Oregon State (+220)
Colorado State (+155)

Point Spread Plays 

Houston (-32.5)
Tulsa (+6.5)
Penn State (-3)
Colorado State (+4)
UCLA (-6.5)

Over/Under Options 

Army at Liberty (Over 52.5)
UTSA at North Texas (Over 59.5)
Oklahoma at Oklahoma State (Under 49.5)

Get 4 Risk-Free Bets up to $1,000 at PointsBet >>


Subscribe: Apple Podcasts | Spotify | Google Podcasts | Stitcher | RadioPublic | Breaker | Castbox | Pocket Casts

Whether you’re new to sports betting or a betting pro, our How To Bet and Sports Betting Strategy and Advice pages are for you. You can get started with our How To Section — including How to Avoid the 7 Biggest Sports Betting Mistakes — or head to more advanced strategy — like Thinking Like an Expert Sports Bettor — to learn more.

Henry John is a featured writer at BettingPros. For more from Henry, check out his archive and follow him @HankTimeHenry.