Early NFL Best Bets & Trends for Week 4 (2025)
It’s time to check out the best bets and trends as we head into Week 4 of the NFL season.
Through three games, the injuries to key players have piled up. Additionally, it seems that flags are being thrown more frequently, disrupting the flow of many games this year.
Will any of that stop in Week 4?
I’ve added multiple early NFL best bets by analyzing trends and other line movement to inform our picks for Week 4.
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Early Week 4 NFL Best Bets & Trends
(Odds courtesy of DraftKings Sportsbook)
Philadelphia Eagles vs. Tampa Bay Buccaneers
It’ll be a battle between two 3-0 squads on Sunday.
The Eagles opened as a 2.5-point favorite (-130) and have since jumped to -3 (-110) at many spots. The Eagles ultimately escaped the Rams with a blocked field goal as time expired. Philadelphia finished with only 288 total yards of offense and went 5-for-14 on third downs. The difference in that game was the red zone. The Rams went 1-for-4 in the red zone, while the Eagles were 3-for-3. However, the Eagles have ultimately not looked like a Super Bowl contender, despite their 3-0 start.
Meanwhile, the Buccaneers are doing way more on offense. Tampa Bay added nearly 350 total yards against the Jets and squeezed out a 29-27 win with a field goal as time expired. Tampa Bay needs to clean up its penalties. The Bucs had 14 penalties that cost them 124 yards. Suppose they’re able to clear that up; the Bucs should find some success against the Eagles at home. This will likely be another close game. The Bucs and Eagles have been in tight games all season long.
Therefore, let’s back the Buccaneers at +3 (-110) at home.
Pick: Buccaneers +3 (-110)
Chicago Bears vs. Las Vegas Raiders
The Chicago Bears picked up their first win of the season with a 31-14 victory over the Dallas Cowboys. Caleb Williams added four touchdown passes, and Ben Johnson won his first game as head coach of the Bears. Ultimately, Chicago still allowed nearly 400 yards of offense to the Cowboys. But the Bears also won the turnover battle, 4-0, which was easily the difference in the game.
This weekend, the Bears will play the Las Vegas Raiders, who already have thrown four interceptions this season. Geno Smith and the Raiders haven’t produced well enough on offense yet. In addition, the Raiders just allowed 41 points to Washington, who played without Jayden Daniels. Nobody should be surprised if the Bears find success against the Raiders and build on the momentum gained from last week’s game. Williams looked sharp, and the defense made big plays when needed.
Yet, the Bears opened at -1.5 (+100) and are now +1.5 (-120). I’ll gladly back the Bears, even on the road, at -105, as slight underdogs. The Bears are coming off a win, while the Raiders gave up 41 points to a team using their backup quarterback.
Pick: Bears Moneyline (-105)