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NFL Week 17 Same Game Parlays & Picks (2025)

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NFL Week 17 is here, and it's time to lock in some best bets and props before the games kick off. Picking matchups against the spread (ATS) and betting on the over/under is more commonplace, but a same-game parlay (SGP) gives us even more added action. Let's find some plus-money NFL Week 17 same-game parlays for every game on the Sunday afternoon slate.

Keep in mind that the odds below are accurate as of writing, but are always subject to change up until kick-off. Keep track of any of the latest NFL injury news and odds movement before locking in any of these SGP bets. Without further ado, let's dive into the best NFL Week 17 same-game parlay bets.

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Best NFL Week 17 Same Game Parlays 

(Odds courtesy of DraftKings Sportsbook unless noted otherwise)

Boost your NFL betting strategy with our Same-Game Parlay (SGP) Tool. Get expert correlations, projections and bet ratings.

Arizona Cardinals at Cincinnati Bengals 

    In case you forgot, the Bengals are terrible at defending opposing tight ends. The defense is allowing a league-worst 90.8 receiving yards and seven receptions per game to the position. We've been targeting the matchup all year, so we'll gladly do it again with one of the league's most prolific tight ends. 

    Trey McBride can realistically go for 100+ yards in this spot. The Arizona tight end has developed a strong connection with Jacoby Brissett. Since the latter took over as the starter, McBride is averaging 82.3 receiving yards, 10.6 targets and eight receptions per game. He's due to bounce back after only having 27 yards last week. Before that, he put up 70+ yards in seven of the prior nine games with Brissett. 

    As McBride does his thing, Michael Carter can also be productive against this weak Cincinnati defense. The Bengals are giving up a league-high 128.3 rushing yards per game to running backs, not to mention 44.9 receiving yards per game to the position (second-most). It's a good spot for Carter, who's entrenched as the Cardinals' lead back amid all the injuries. He's put up 94 and 65 total yards in the past two weeks as the starter. 

    Meanwhile, Chase Brown can do the same on the other side. After putting up 109 total yards last week, Brown continues to be consistently productive. He has averaged 102.3 total yards over his past nine games, with 90+ combined yards in eight of the nine contests. The Bengals lead back is getting it done as both a rusher and pass-catcher right now. He'll take on an Arizona defense allowing 112.7 rushing yards per game to running backs (fifth-most in NFL), and 34.7 receiving yards per game to the position (10th-most). 

    Parlay Odds: +455

    Pittsburgh Steelers at Cleveland Browns 

      When Pittsburgh and Cleveland met earlier this season, it was a 24-9 victory for the Steelers at home. In this rematch, we should see another low-scoring game with Cleveland hosting. The Browns' defense has struggled lately, but we should see one last strong effort from the unit in a divisional rivalry matchup at home. It helps that Myles Garrett will be vying for one more sack to get the single-season record. 

      The weather in Cleveland also projects to be ugly, with a 90% chance of rain and 20 miles per hour (MPH) winds. As for Pittsburgh, it can clinch the AFC North this week with a win or a Ravens loss. If the latter happens on Saturday night, the Steelers won't have anything to play for on Sunday. Maybe we get some rested starters on offense? The total is already on the low end, but don't expect much scoring in this game. 

      Speaking of the Pittsburgh offense, it should lean on the run game with the aforementioned weather conditions. Plus, Cleveland is allowing only 185.6 passing yards per game to opposing quarterbacks, the second-fewest in the NFL. Don't expect Aaron Rodgers to be chucking it around as much as he did last game, when he threw for 266 yards on 41 attempts against Detroit. DK Metcalf's suspension also notably downgrades the Steelers' passing game as Rodgers loses his top target. 

      On the other side, Shedeur Sanders faces a Steelers defense allowing 267.5 passing yards per game to quarterbacks. It's the second-highest mark in the league. Despite the weather, Sanders has a good shot at going over his yardage mark. Cleveland could be a more pass-focused offense this week with Quinshon Judkins out. The run game may be quiet, forcing Sanders into more attempts. 

      Parlay Odds: +484 at FanDuel Sportsbook

      New Orleans Saints at Tennessee Titans 

        After a quiet middle part of the season, Tony Pollard has been a force lately. He's run for 100+ yards in three straight games while averaging 6.1 yards per carry in this stretch. The Titans are leaning on the run and feeding Pollard plenty. He's seen 25, 14 and 21 carries in these past three games. The Tennessee tailback takes on a Saints defense allowing 107.1 rush yards per game to running backs, the seventh-most in the NFL. 

        On the New Orleans side of things, let's target two pass-catchers who should be in line for productive games. Both Chris Olave and Juwan Johnson are clear favorite targets of Tyler Shough in the Saints' passing game. They also get a good matchup here. The Titans are allowing the eighth-most receiving yards per game to wide receivers and a decent 51.3 yards per game to tight ends. 

        Olave just put up 148 receiving yards on 10 receptions and 16 targets last week. He's now averaging 75.5 yards per game in eight games with Shough at quarterback. That includes 70+ yards in four of the last six contests, averaging 80.7 yards per game in this stretch. As for Johnson, he just had one of his better games of the year, with eight catches for 89 yards. He's averaging a solid 55.7 yards per game over the past six games, with 38+ yards in five of them. Johnson can get to 40 in this matchup. 

        Parlay Odds: +450

        Jacksonville Jaguars at Indianapolis Colts 

            Trevor Lawrence has the Jacksonville passing attack rolling lately. He threw for 279 yards against a tough Denver defense last week and put up 330 yards the game before versus the Jets. He's also averaging 267.6 passing yards per game over the last five weeks. Let's back him to keep it going this week against a shaky Colts secondary. 

            The Indianapolis defense is allowing 266.3 passing yards per game to opposing quarterbacks this year (third-most in the NFL). Lawrence had 244 yards against the Colts earlier this month, but that was also with Jacksonville up big at halftime as the offense leaned on the run late. Philip Rivers has clearly made the Colts' passing attack more dangerous since that game, and he can force the Jaguars to keep their foot on the gas in the second half. 

            Lawrence's top weapon continues to be Jakobi Meyers. The Jaguars wideout is averaging 59.8 receiving yards and 7.2 targets per game over the past six games. The yards haven't always been there, but Lawrence is looking Meyers' way often. The Colts, meanwhile, are allowing the second-most receiving yards per game to opposing receivers (170.1). It's a good matchup for Meyers to have success. He only had 39 yards versus Indianapolis last time out, though he did see a team-high 10 targets in that game. 

            On the Colts' side, Jonathan Taylor's yards could be limited in a tough matchup. Jacksonville is allowing a league-low 87.3 rushing yards per game, including just 68 yards per game to opposing running backs. As for Taylor, his efficiency and production have seen a notable dip recently. He's averaging 3.5 yards per carry over the past five games, while gaining 70 yards per game in this stretch. Taylor had 74 yards on 21 carries against the Jaguars previously, and he could be held to fewer than 75 yards yet again. 

            Parlay Odds: +430

            Tampa Bay Buccaneers at Miami Dolphins 

              Since returning from injury, Bucky Irving has stepped right into the lead ball-carrier role for Tampa Bay. He's now seen 19, 16 and 15 carries in his three games back. He's also run for 71 and 60 yards in the past two games with that workload. Irving now faces a Miami defense giving up 105.9 rush yards per game to running backs, the seventh-most in the league. The talented Tampa Bay tailback can get to 60+ yards in this matchup, especially since he's done it six times in his last seven games. 

              Meanwhile, Miami's running back should be in line for a productive pass-catching day. Tampa's defense is giving up a league-high 53.6 receiving yards per game to opposing running backs. That sets up perfectly for De'Von Achane, who is one of the better receiving backs in the league. He's averaging 30.6 receiving yards per game this year, with 24+yards in five of the last eight games. Look for Quinn Ewers to dump it off to Achane enough for him to clear 25 yards. 

              Speaking of Ewers, the rookie quarterback targeted Jaylen Waddle nine times last week in his first NFL start. In turn, Waddle put up 72 yards on five catches as the Dolphins' leading pass-catcher. Look for him to be a favorite option for Ewers again this week. Waddle also now has 50+ receiving yards in eight of his last 11 games. 

              Parlay Odds: +410

              New England Patriots at New York Jets 

                As of this writing, the Patriots' backfield is a bit murky. Rookie standout TreVeyon Henderson suffered a concussion last week and is currently questionable to play. He practiced in full on Friday, but his status is still up in the air. There's a decent chance he fails to clear the concussion protocol before Sunday's matchup against the Jets. 

                Let's take an early stand and bank on Henderson sitting, which puts Rhamondre Stevenson into the lead-back role for New England. If that's the case, Stevenson has a great opportunity at reaching the end zone. The Jets have given up 15 rushing touchdowns and 23 total touchdowns to running backs through 15 games this year. Stevenson scored last week after Henderson went out, and he can make it two straight in this matchup. 

                Meanwhile, New York's running back could have a long day. The Patriots boast one of the best rush defenses in the league, allowing just 74.7 yards per game to running backs (third-fewest in the NFL). It's not ideal for Breece Hall, who's been very underwhelming recently. He's averaging 48.3 rush yards over the last six games, with fewer than 60 yards in five of the six contests. That includes when the Patriots held him to 58 yards in the previous meeting. 

                The tough matchup is one thing, but the expected game flow is another. New England is a double-digit favorite in this game and should be leading for much of the afternoon. That likely means fewer carries than normal for Hall, who hasn't been too productive with his touches anyway. 

                That game script also means more passing for the Jets' offense, bringing us to Adonai Mitchell. He's established himself as the team's top wideout for a month now. Getting to 40+ yards this week is a low bar for someone who's now done it in four of the last five games. Mitchell is a favorite target of Brady Cook, and he should do just enough to help cash this SGP. 

                Parlay Odds: +410

                Seattle Seahawks at Carolina Panthers 

                  If you've been reading these SGP articles all season, you know what to do if Seattle is involved. Jaxon Smith-Njigba's consistent high-end production is truly remarkable, and it continues to be profitable. He now has 90+ receiving yards in 13 out of 15 games this season after getting there again last week. Carolina's mid-tier pass defense shouldn't hold Smith-Njigba down from getting to 90+ yards one more time. He's also averaging a strong 109.1 yards per game overall. 

                  Seattle tailback Kenneth Walker can also be productive in this matchup. The Panthers are allowing 102.9 rushing yards per game to running backs (ninth-most in the NFL). Even though Zach Charbonnet is regularly involved, Walker is still the first man up on carries. He's also now run for 50+ yards in five of his last seven games, and in eight of his last 12 contests. It's a low bar for him to hit, despite Charbonnet taking touches and snaps away. 

                  After some big games in the middle of the season, Rico Dowdle's rushing production has really dipped over the past two months. He's averaging just 45.3 rushing yards over the past six games, with fewer than 50 yards in four of his last five contests. The yards could be capped again this week against a stout Seattle defense. The Seahawks are allowing the fourth-fewest rushing yards per game to opposing running backs, and the expected game flow likely results in more passing from the Carolina offense while trailing. 

                  Parlay Odds: +460

                  New York Giants at Las Vegas Raiders 

                    It's been an underwhelming rookie season overall for Ashton Jeanty. Of course, playing on a bad Raiders team doesn't help. This week, though, he has a chance for a productive stat line against a poor rush defense. The Giants are allowing 121.9 rushing yards per game to running backs this season, the second-most in the NFL. It's a great spot for Jeanty, who we know will get the bell-cow workload for Las Vegas. Plus, he just exploded for 128 yards against Houston last week.

                    Meanwhile, the other lead running back in this game gets a favorable matchup as well. The Raiders are allowing 79.1 rushing yards per game to lead running backs over the past eight games. That includes 70+ rushing yards to a lead back in seven of the last eight contests. Tyrone Tracy Jr. is averaging 66.3 rushing yards and 15.7 carries per game over the past six games since Cam Skattebo went down. He's the clear No. 1 RB seeing strong volume for New York, with 60+ rush yards in five of the last six games in this role. 

                    Another key contributor for the Giants this week should be Wan'Dale Robinson. The slot wideout only had 19 yards on three catches last game, but a bounce-back opportunity is here. The Raiders are giving up the sixth-most receptions per game to opposing wide receivers. That's ideal for Robinson, who has been a top target of Jaxson Dart, especially on quick passes. Robinson is averaging 5.4 receptions per game overall this season, and 6.1 over the past seven contests. He has five or more catches in eight of the last 11 games. 

                    Parlay Odds: +455

                    Philadelphia Eagles at Buffalo Bills 

                      It hasn't been the most productive season for Saquon Barkley. Yet, the Eagles' stud running back has woken up lately. He ran for 132 yards last week and 122 yards three weeks ago. Barkley also had 78 yards in the blowout win over Las Vegas, sandwiched between those performances. 

                      Philadelphia is leaning on the run right now, with Barkley seeing 20+ carries in three straight games. Expect more of the same this week against the Bills. Their defense is allowing the fourth-most rushing yards per game (144.3), while giving up 5.4 yards per carry (second-most). It's a good spot for Barkley to keep it going with another solid stat line. 

                      One player to fade from the Philly offense is tight end Dallas Goedert. The Bills are among the league's best at defending the position, allowing just 32.9 receiving yards per game to opposing tight ends (second-fewest in the NFL). Buffalo is also giving up a league-low 2.8 receptions per game to tight ends. Goedert has had some good games lately, but he's still averaging just 41.6 yards per game this year. He's also been held to fewer than 33 yards in six of his last nine games. 

                      On the Buffalo side, look for Josh Allen to use his legs to make plays. We know he's always capable of doing so, but the Eagles have been vulnerable to running quarterbacks. The defense has a top-tier secondary that should force Allen to scramble more often as coverage and pass protection break down. Allen only had 17 rushing yards last week, but he's still averaging 36.8 yards per game on the ground this year. He also has 30+ rush yards in 10 out of 15 contests. 

                      Parlay Odds: +440

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