NFL Week 3 Odds, Picks & Predictions: Chiefs vs. Colts (2022)

Here are our odds, picks, and predictions for this NFL Week 3 matchup: Chiefs vs. Colts.

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NFL Week 3 Odds, Picks & Predictions: Chiefs vs. Colts

Indianapolis is finally home after the offense struggled in two divisional road games. Unfortunately for them, their opponent is the red-hot Chiefs. The Chiefs have moved on from WR Tyreek Hill pretty quickly, producing the 3rd ranked offensive DVOA through two weeks, led by their passing attack. The Colts provide a favorable matchup after allowing effective passing days from QB Davis Mills and QB Trevor Lawrence, clocking the 29th ranked pass defense DVOA. QB Patrick Mahomes and the company will have a field day.

Meanwhile, QB Matt Ryan has not been the upgrade over Carson Wentz that the Colts wanted. He’s been dreadful through two games with one touchdown, four interceptions, and a putrid 31.2 QBR. The Kansas City defense has shut down both opponents’ running attacks, so the Colts are in for a long afternoon if Ryan is forced to make plays with a banged-up receiving corps.

Pick: Lean Chiefs -6.5, u50.5

What is Betting Against the Spread?

Betting “against the spread” refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

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