NFL Week 4 Odds, Picks & Predictions: Vikings vs. Saints (2022)

Here is an early look at our odds, picks, and predictions for the NFL Week 4 game, Vikings vs. Saints.

And check out a few of our other favorite bets for Week 4:

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NFL Week 4 Odds, Picks & Predictions: Vikings vs. Saints

The Saints come into this matchup with the Vikings trying to get the offense right. QB Jamies Winston has struggled while nursing a back injury, grading out below Davis Mills and Cooper Rush on PFF through three weeks. However, with RB Alvin Kamara back in the fold, the running game may get some relief after going up against a Tampa front seven and a surprisingly stout Carolina run defense. Minnesota has ranked 31st in run defense DVOA in the early season, making it a matchup the Saints can exploit.

Minnesota will look to counter with a banged up running attack of their own. Against a New Orleans defense that hasn’t allowed an opposed quarterback over 215 yards, this could pose a challenge. A lot will be asked of QB Kirk Cousins in a tough matchup 4,000 miles from home, which may have the Vikings leaving London on a sour note.

Saints +2.5, Lean u43.5

What is Betting Against the Spread?

Betting “against the spread” refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

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