2025 NCAA Tournament PrizePicks Predictions: Sweet 16 (Friday)
After an exciting slate yesterday, we’re right back for some more with four more Sweet 16 games of the 2025 NCAA Tournament.
Like every PrizePicks article, we’ll give out four different player predictions you can use for a four-leg Power Play entry. A two-leg Power Play entry will give you implied odds of -137 for each prediction. A three-leg Power Play entry will give you implied odds of -141. A four-leg NBA PrizePicks Power Play entry will give you implied odds of -128 for each prediction.
Getting -128 on the same prediction is better than -137 or -141. Here are our top PrizePicks player predictions for today’s action.
Remember that a Flex play can still win if one pick misses, but you’d get lower payouts.
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