The College Baseball World Series gets started today. There are numerous games on the slate for today’s regionals, making it challenging to keep track of everything.
Therefore, I did the hard part for you. I’ve added two best bets to consider for tonight’s portion of the regionals slate. Here are our top college baseball picks for Friday’s regional game Kansas vs. Creighton.
Get instant alerts when a line reaches your target via the BettingPros App >>
2025 College Baseball World Series Picks: Kansas vs. Creighton
(2024 College World Series odds courtesy of DraftKings Sportsbook)
Kansas (-145) vs. Creighton (+114) | O/U 12.0 (-115/-115)
Starting Pitcher Matchups:
- Kansas: Dominic Voegele, RHP (7-4) | 91 Innings | 5.34 ERA
- Creighton: Dominic Cancellieri, RHP (2-1) | 51 Innings | 1.94 ERA
It’ll likely be the battle of the Dominics in tonight’s Kansas-Creighton matchup. Kansas has posted a higher batting average this season and faced a much tougher strength of schedule. Yet, over the last 10 games, Creighton has performed better overall.
The Blue Jays are red hot, hitting .304 over the last 10 games. They’ve also added a .328 wOBA on offense. Meanwhile, the pitching has limited teams to a .387 average over the last 10 games, while Kansas has allowed a .690 average.
In addition, Creighton’s Dominic Cancellieri has been sensational this year. He’s thrown more than 50 innings and has a 1.94 ERA with a 1.25 WHIP. He’s struck out more than one batter per inning this season and has an xFIP of 4.42.
Meanwhile, Kansas will likely pitch Dominic Voegele, who has a 5.34 ERA with fewer strikeouts and an xFIP that is higher at 4.78. Additionally, Creighton’s bullpen has outperformed Kansas’s this season. Creighton has several pitchers who can strike out at a high rate. Kansas doesn’t.
Let’s ride with Creighton at +115 on the Moneyline.
Pick: Creighton (-115)

