Colts vs. Bills: 2023 NFL Preseason Odds, Picks & Predictions (Saturday)

The 2023 NFL preseason is here! While the NFL regular season will bring a ton of action, we’ll have you covered through the summer as there are plenty of chances to bet and money to make. We’ll have you covered throughout the 2023 NFL preseason with our best odds, picks, and predictions for each and every game. Let’s dive into the action as the first full week of the preseason gets underway. Here are our top odds, picks, and predictions for Saturday’s NFL preseason games. Here’s a closer look at Colts vs. Bills.

2023 NFL Preseason Odds & Picks: Colts vs. Bills

Here are our top picks and predictions for Saturday’s NFL preseason action.

Colts vs. Bills

The NFL world will get its first chance to see Colts rookie QB Anthony Richardson in live, NFL action. The question is, for how long? Richardson has been announced as the starter and will be followed by Gardner Minshew. I wouldn’t be surprised to see Indianapolis play its starters for at least a series. Meanwhile, Richardson could see extended reps as the Colts get a close look at how he does in game situations. Meanwhile, I’d imagine Buffalo plays it safe and sits most, if not all of their starters after Dion Dawkins and Damien Harris suffered injuries this week. The Bills are one of the most stable teams in the league and don’t have many starting position battles to sort out in the preseason. While laying this many points in the preseason is risky, I expect Indy to take this game more seriously. Plus, the Colts have a stronger group at QB with Richardson, Minshew and Sam Ehlinger than Buffalo, who will likely play Kyle Allen and Matt Barkley Saturday.

Pick: Colts -3.5 (-110)

-Matt Barbato