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Cowboys vs. 49ers: NFL Week 5 Odds & Picks (2023)

NFL Sunday Night Football Anytime Touchdown Scorer Picks: Cowboys vs. 49ers (Week 5)

NFL Underdogs took a bit of a step back in Week 4, but even in a down week, we still saw five Underdogs cover the spread, and three won outright (Not including the Ravens, who shifted to a favorite before kickoff). There will be weeks like this throughout the season, and this just tells me that more chaos is on the way soon.

Week 5 begins the bye weeks for NFL teams, and unfortunately, less football to watch. An early look at the board reveals a couple of double-digit underdogs and several games with a spread of less than 3 points. Here are all of my top underdog picks for the week. Below we dive into Cowboys vs. 49ers.

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      NFL Week 5 Top Underdog Bets: Cowboys vs. 49ers

      Dallas Cowboys (+3.5) vs. San Francisco 49ers

      I saved the best for last – I couldn’t pass up betting on the best game of the 2023 NFL season thus far. This is easily my favorite bet of the week. Of course, it’s hard to feel good about going against this dominant 49ers team, but here I am explaining why you should.

      Both teams have looked excellent over the first month of the season. The 49ers had a couple of semi-close divisional games, and besides a weird loss to the Cardinals, the Cowboys have blown out their other three opponents. We know the 49ers have great units up front on the offensive and defensive lines. This Cowboys team is one of the few that can match their physicality on both sides of the ball. Micah Parsons and Demarcus Lawrence against Trent Williams and company will be the matchup to watch all night. Pressuring and disrupting Brock Purdy is the recipe to neutralize this 49ers offense, and no team is more equipped to do so than the Cowboys. Trevon Diggs would have been very useful against Brandon Aiyuk’s downfield abilities, but I think Stephon Gilmore, Malik Hooker and Co. can pick up the slack there, especially if this front seven can get pressure on Purdy.

      On the other side of the ball, Zack Martin and this offensive line are up for the challenge against Nick Bosa and this strong defensive line. I’m expecting Dan Prescott and the passing game to go after this secondary, which is pretty average compared to the rest of this team. Ceedee Lamb is the key player for me in this matchup. I'm betting on the Cowboys’ defense to keep this one close and possibly win this game, as this is a very important game for implications on the NFC’s 1 seed.

      Bet: Cowboys +3.5 vs. 49ers (-110)

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