NCAA Tournament Odds: Round 1 Spreads (March Madness)

It’s about to get real for this year’s March Madness tournament, as the Round of 64 gets underway soon. We'll have 16 games on Thursday and another 16 on Friday. It's a lot of basketball to keep track of, which we would like to help make a little easier for you.

How so? By providing you with a list of all the first-round games, with spreads and win percentages.

Go premium to view top prop bets based on Cover Probability, Expected Value & Star Rating >>

2026 NCAA Tournament Round 1 Spreads & Win Percentages

(Odds via DraftKings Sportsbook)

Thursday, March 19th

No. 9 TCU vs. No. 8 Ohio State

Spread: TCU +2.5 (-110) | Ohio State -2.5 (-110)
Win Percentage: TCU 45.45% | Ohio State 58.68%

No. 13 Troy vs. No. 4 Nebraska

Spread: Troy +13.5 (-118) | Nebraska -13.5 (-102)
Win Percentage: Troy 13.33% | Nebraska 90.91%

No. 11 USF vs. No. 6 Louisville

Spread: USF +4.5 (-110) | Louisville -4.5 (-110)
Win Percentage: USF 37.04% | Louisville 67.21%

No. 12 High Point vs. Wisconsin

Spread: High Point +10.5 (-102) | Wisconsin -10.5 (-118)
Win Percentage: High Point 22.22% | Wisconsin 83.33%

No. 16 Sienna vs. No. 1 Duke

Spread: Sienna +28.5 (-118) | Duke -28.5 (-102)
Win Percentage: Sienna 2.78% | Duke 99.5%

No. 12 McNeese State vs. No. 5 Vanderbilt

Spread: McNeese State +11.5 (-112) | Vanderbilt -11.5 (-108)
Win Percentage: McNeese State 16.67% | Vanderbilt 87.5%

No. 14 North Dakota State vs. No. 3 Michigan State

Spread: North Dakota State +16.5 (-118) | Michigan State -16.5 (-102)
Win Percentage: North Dakota State 9.09% | Michigan State 94.74%

No. 13 Hawaii vs. No. 4 Arkansas

Spread: Hawaii +15.5 (-108) | Arkansas -15.5 (-112)
Win Percentage: Hawaii 10.53% | Arkansas 93.55%

No. 11 VCU vs. No 6 North Carolina

Spread: VCU +2.5 (-108) | North Carolina -2.5 (-112)
Win Percentage: VCU 43.48% | North Carolina 60.78%

No. 16 Howard vs. No. 1 Michigan

Spread: Howard +31.5 (-115) | Michigan -31.5 (-105)
Win Percentage: Howard 2.78% | Michigan 99.5%

No. 11 Texas vs. No. 6 BYU

Spread: Texas +1.5 (+100) | BYU -1.5 (-120)
Win Percentage: Texas 44.64% | BYU 59.68%

No. 10 Texas A&M vs. No. 7 Saint Mary's

Spread: Texas A&M+3.5 (-118) | Saint Mary's -3.5 (-102)
Win Percentage: Texas A&M 42.37% | Saint Mary's 61.83%

No. 14 Penn vs. No. 3 Illinois

Spread: Penn +24.5 (-110) | Illinois -24.5 (-110)
Win Percentage: Penn 4.76% | Illinois 98.48%

No. 9 Saint Louis vs. No. 8 Georgia

Spread: Saint Louis +2.5 (-118) | Georgia -2.5 (-102)
Win Percentage: Saint Louis 44.64% | Georgia 59.68%

No. 14 Kennesaw State vs. No. 3 Gonzaga

Spread: Kennesaw State +21.5 (-115) | Gonzaga -21.5 (-105)
Win Percentage: Kennesaw State 5.88% | Gonzaga 97.56%

No. 15 Idaho vs. No. 2 Houston

Spread: Idaho +23.5 (-110) | Houston -23.5 (-110)
Win Percentage: Idaho 4.35% | Houston 98.77%

Friday, March 20th

No. 10 Santa Clara vs. No. 7 Kentucky

Spread: Santa Clara +3.5 (-115) | Kentucky -3.5 (-105)
Win Percentage: Santa Clara 42.37% | Kentucky 61.83%

No. 12 Akron vs. No. 5 Texas Tech

Spread: Akron +7.5 (-105) | Texas Tech -7.5 (-115)
Win Percentage: Akron 27.03% | Texas Tech 77.27%

No. 16 Long Island University vs. No. 1 Arizona

Spread: Long Island University +30.5 (-108) | Arizona -30.5 (-112)
Win Percentage: Long Island University 1.96% | Arizona 99.9%

No. 14 Wright State vs. No. 3 Virginia

Spread: Wright State +18.5 (-115) | Virginia -18.5 (-105)
Win Percentage: Wright State 7.14% | Virginia 96.55%

No. 15 Tennessee State vs. No. 2 Iowa State

Spread: Tennessee State +24.5 (-110) | Iowa State -24.5 (-110)
Win Percentage: Tennessee State 4.35% | Iowa State 98.77%

No. 13 Hofstra vs. No. 4 Alabama

Spread: Hofstra +11.5 (-110) | Alabama -11.5 (-110)
Win Percentage: Hofstra 15.38% | Alabama 88.89%

No. 9 Utah State vs. No. 8 Villanova

Spread: Utah State -1.5 (-110) | Villanova +1.5 (-110)
Win Percentage: Utah State 55.56% | Villanova 48.78%

No. 9 Iowa vs. No. 8 Clemson

Spread: Iowa -2.5 (-102) | Clemson +2.5 (-118)
Win Percentage: Iowa 57.45% | Clemson 46.73%

No. 12 Northern Iowa vs. No. 5 St. John's

Spread: Northern Iowa +9.5 (-108) | St. John's -9.5 (-112)
Win Percentage: Northern Iowa 20% | St. John's 84.25%

No. 10 UCF vs. No. 7 UCLA

Spread: UCF +5.5 (-108) | UCLA -5.5 (-112)
Win Percentage: UCF 32.79% | UCLA 71.43%

No. 15 Queens University vs. No. 2 Purdue

Spread: Queens University +25.5 (-110) | Purdue -25.5 (-110)
Win Percentage: Queens University 4.35% | Purdue 98.77%

No. 13 California Baptist vs. No. 4 Kansas

Spread: California Baptist +14.5 (-118) | Kansas -14.5 (-102)
Win Percentage: California Baptist 11.76% | Kansas 92.31%

No. 15 Furman vs. No. 2 UConn

Spread: Furman +20.5 (-108) | UConn -20.5 (-112)
Win Percentage: Furman 5.56% | UConn 97.83%

No. 10 Missouri vs. No. 7 Miami

Spread: Missouri +1.5 (-105) | Miami -1.5 (-115)
Win Percentage: Missouri 47.62% | Miami 56.52%

More NCAA Tournament Picks

#1 Duke vs. #16 Siena
#8 Ohio State vs. #9 TCU
#5 St. John’s vs. #12 Northern Iowa
#4 Kansas vs. #13 Cal Baptist
#6 Louisville vs. #11 South Florida
#3 Michigan State vs. #14 North Dakota State
#7 UCLA vs. #10 UCF
#2 UConn vs. #15 Furman

#1 Arizona vs. #16 LIU
#8 Villanova vs. #9 Utah State
#5 Wisconsin vs. #12 High Point
#4 Arkansas vs. #13 Hawai’i
#11 Texas vs. North Carolina State
#3 Gonzaga vs. #14 Kennesaw State
#7 Miami (FL) vs. #10 Missouri
#2 Purdue vs. #15 Queens

#16 UMBC vs. Howard
#8 Georgia vs. #9 Saint Louis
#5 Texas Tech vs. #12 Akron
#4 Alabama vs. #13 Hofstra
#11 Miami OH vs. SMU
#3 Virginia vs. #14 Wright State
#7 Kentucky vs. #10 Santa Clara
#2 Iowa State vs. #15 Tennessee State

#16 Prairie View A&M vs. Lehigh
#8 Clemson vs. #9 Iowa
#5 Vanderbilt vs. #12 McNeese
#4 Nebraska vs. #13 Troy
#6 North Carolina vs. #11 VCU
#3 Illinois vs. #14 Penn
#7 Saint Mary’s vs. #10 Texas A&M
#2 Houston vs. #15 Idaho