Last week, the Tennessee Titans upset the Cleveland Browns, the Minnesota Vikings shut out the Washington Commanders, the Pittsburgh Steelers picked up a huge win over the Baltimore Ravens and the New Orleans Saints pulled off the upset of the week by shocking the Tampa Bay Buccaneers in Tampa. This week, there are plenty of games with huge playoff implications. Additionally, I'm picking two upsets, as favored teams walk into trap situations. Below are my top NFL Week 15 pick’em pool predictions.
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NFL Week 15 Pick’em Pool Predictions (2025)
Baltimore Ravens vs. Cincinnati Bengals
Maybe it's an overreaction, but is it fair to say that the Ravens are done? After fighting to get over .500, they've lost back-to-back games, and they now have to travel to Cincinnati to play a team that beat them 32-14 on Thanksgiving.
Joe Burrow's return has seemingly instilled confidence in both the Bengals' offense and defense, as the team went toe-to-toe with the Buffalo Bills last week. Though they lost 39-34, Burrow threw for 284 yards and four touchdowns.
The Ravens have the seventh-worst pass defense, so I expect another huge game from Burrow. And while the Bengals' defense is still allowing 24.7 more yards per game than any other team, they forced five Ravens turnovers two weeks ago, and they held Baltimore to 346 yards.
Lamar Jackson has not looked like himself of late, completing fewer than 60% of his passes in five consecutive games, while throwing just two touchdowns and four interceptions during that span. He also hasn't rushed for more than 50 yards since Week 1. The Bengals may have the worst defense in football, but I don't trust Jackson to take advantage of any matchup right now.
Pick: Cincinnati Bengals
Los Angeles Chargers vs. Kansas City Chiefs
The Chiefs defense has only produced 25 sacks this season, but three of those came in Week 1 against the Chargers. That was when the Chargers' offensive line was much healthier than it is now. The line has been depleted. On Sunday night, the Eagles pressured Justin Herbert on more than 68% of his dropbacks, according to NFL Next Gen Stats.
The Chargers have allowed 47 sacks this season, and I worry that under constant pressure, Herbert isn't going to be able to do much against the Chiefs. Despite their 6-7 record, the Chiefs rank seventh in scoring defense, seventh in rushing defense, ninth in total defense and 13th in pass defense.
The Chiefs' offense has struggled at times, but it still ranks seventh in total yards, 11th in total points and fourth in passing. The Chargers have the fifth-best pass defense in the NFL, but they have benefited by playing some of the worst passing attacks in the league over the last couple of weeks. This win won't get the Chiefs into the playoffs, but it will keep their chances alive for one more week.
Pick: Kansas City Chiefs
Green Bay Packers vs. Denver Broncos
Two of the best defenses in football clash in Denver on Sunday, as the Broncos find themselves 2.5-point underdogs against the Packers. The Broncos have rattled off 10 consecutive wins, but they haven't always looked that good picking up those victories, as eight of their wins have come in one-possession games.
One huge advantage that the Broncos have is that they're playing at home, where they've yet to lose this season. While the Packers have a 4-1-1 away record, only one of their road victories has been by more than seven points. After rattling off three wins against NFC North opponents, I worry that this is a letdown spot for the Packers, as they get ready to travel to Chicago for a massive meeting against the Bears.
This game will ultimately come down to whether the Broncos' pass rush can get to Jordan Love or not. The Broncos lead the NFL with 55 sacks, while the Packers have allowed just 18, which is the fourth-fewest in the league. Look for the Broncos to keep Love off balance more than he's used to, as the home team makes enough stops to pick up a low-scoring close win.
Pick: Denver Broncos
Detroit Lions vs. Los Angeles Rams
This is one of those games where almost every stat point towards the Rams winning. Yet, I'm going with the Lions. The Rams have the second-ranked scoring defense in the league, allowing just 17.5 points per game. They're allowing just 6.5 yards per pass attempt and 3.9 yards per rush. Offensively, the Rams rank fourth in total yards and points per game.
Yet, this is a bit of a trap game for the Rams. After this game, the Rams will travel to Seattle to play the Seahawks on Thursday Night Football, in a game that will likely decide who wins the NFC West. The Rams are currently the top seed in the NFC, and even if they lose on Sunday, they will still take the top spot with three wins to end the year.
Meanwhile, the Lions are desperate. Their secondary continues to take a beating, as they lost Brian Branch for the season last week, but the offense is clicking. They're averaging a league-high 30.3 points per game, and though the offensive line has been much-maligned, they gave up just one sack to the Cowboys last week. The Rams have swelled to 5.5-point favorites, but considering what's at stake for the Lions in a crowded NFC, I expect them to steal a game almost no one is expecting them to win.
Pick: Detroit Lions
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Phil Wood is a featured writer at BettingPros. For more from Phil, check out his archive and follow him @Phil_Wood_Jr.

