The Seattle Mariners are now -650 Moneyline favorites at 86.67% implied odds to win the American League Championship Series (ALCS) after taking a commanding 2-0 series lead while winning both games on the road. Those odds are in line with the historical trends as laid out by MLB’s Sarah Langs on X.
In postseason history, teams taking a 2-0 lead in any best-of-seven series have gone on to take that series 78 of 93 times (83.9%)
In series with the current 2-3-2 format, teams winning both Games 1 and 2 on the road have prevailed in the series 24 of 27 times (88.9%) https://t.co/6AgsX49kC3
— Sarah Langs (@SlangsOnSports) October 14, 2025
How do we see Wednesday’s Game 3 playing out? Read on for my top MLB picks & predictions for Wednesday, October 15th.
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Wednesday’s Best MLB Picks & Predictions
(Odds courtesy of DraftKings Sportsbook)
Toronto Blue Jays (+112) at Seattle Mariners (-137) | O/U 7.0 (-105/-115)
After Seattle beat Detroit 3-2 at home in Game 5 of the American League Division Series (ALDS), it extended the run of nine straight playoff games at T-Mobile Park (since 2001) where the two teams combined for six or fewer runs. Only three other ballparks (Tropicana Field from 2008-2010, Baltimore Memorial Stadium from 1979-1983, Yankee Stadium from 1956-1958) had a streak that even lasted seven such games.
In losing the regular season series to Toronto 4-2, Seattle’s starting pitchers were beaten up for a 6.54 ERA, while the bullpen pitched to a 2.54 ERA in those six games. But Seattle’s starters have done an outstanding job thus far, especially in Game 1, when it held the Blue Jays to just one run (a George Springer leadoff home run), which was the first time in nine games Toronto scored fewer than four runs.
In Game 1, Bryce Miller retired 13 straight batters from the second to sixth innings, and finished with a season-best one run over six innings, after he recorded fewer than six innings in 18 of his previous 19 starts.
I have faith in George Kirby to continue that momentum, especially at home, where his 3.38 ERA and .227 opponents’ batting average were much better than his 5.16 ERA and .279 opponents’ batting average in road starts. I also expect Shane Bieber to match zeros despite his rocky ALDS start against the Yankees, as he pitched to a .169 opponents’ batting average in three road starts in the regular season this year.
The over has cashed in each of Toronto’s last six games as underdogs against Seattle, but at pitcher-friendly T-Mobile Park, that streak should come to an end.
Pick: Under 7.0 Runs (-115)
Mike Spector is a featured writer at BettingPros. For more from Mike, check out his archive and follow him @MikeSpector01