After 155 games played, the final week of regular season baseball is finally here. The MLB season can be a slog, so it’ll be nice to get some truthfully meaningful baseball in a few short days.
Here are the best PrizePicks plays worth considering for today, Wednesday, Sept. 27.

Wednesday’s Best MLB PrizePicks Player Predictions
This season: 70-59-8
This Astros and Mariners series is a little taste of some playoff baseball. It’s the Wild West in the AL West, and there are huge playoff ramifications for both of these teams, along with Texas. A half-game separates Seattle and Houston, so the leash will be short on both pitchers if they get into trouble, and the moment could get to the Mariners’ rookie Bryce Miller here.
After 155 games played, the final week of regular season baseball is finally here. The MLB season can be a slog, so it’ll be nice to get some truthfully meaningful baseball in a few short days.
Here are the best PrizePicks plays worth considering for today, Wednesday, Sept. 27.

Wednesday’s Best MLB PrizePicks Player Predictions
This season: 70-59-8
This Astros and Mariners series is a little taste of some playoff baseball. It’s the Wild West in the AL West, and there are huge playoff ramifications for both of these teams, along with Texas. A half-game separates Seattle and Houston, so the leash will be short on both pitchers if they get into trouble, and the moment could get to the Mariners’ rookie Bryce Miller here.
He has been solid over the course of the season, but facing the Astros is no easy task for any starter. They have the best wRC+ (145) and 2nd lowest K% (16.3%) against righties over the last 30 days. Miller faced them a little over a month ago, and while he did shut them down, he didn’t strike out many and finished with only two strikeouts. Miller is basically a two-pitch pitcher and not really a punchout pitcher, either. He ranks in the 37th percentile in CSW% and 53rd in K% among all starters this season. He has exceeded this number in just 10 of his 24 starts this year.
Jose Berrios Over 28.5 Pitcher Fantasy Score
These teams just squared off a few days ago, and Berrios did just fine against the Yankees. Most starters do when they face them these days. They have an 89 wRC+ (t-6th worst) and 27.1% K% (3rd worst) over the last 30 days against righties. 13 of the last 20 right-handed starters to face them have exceeded this number. Berrios didn’t quite get north of this line a few days ago, falling an out short of a quality start. When he left the game at 5.2 innings, the bullpen couldn’t prevent the inherited runner from scoring either, which knocked his score down to 23 points. Pitching at home today, Berrios should rebound today and find a quality start with around six punchouts. That
There is no stopping Skubal’s strikeouts right now. He has seven or more in seven straight starts. He’s one of the best young and upcoming lefties in the game and ranks in the 100th percentile in xERA and xFIP, 99th in K%, and 98th in CSW%. This Royals roster really isn't anything to be concerned about. Their 93 wRC+ since the start of August is 19th among all teams. Ride the strikeout wave with Tarik and his high-octane heater.

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Tyler Gentile is a featured writer at BettingPros. For more from Tyler, follow him @808Paperboi.