After a thrilling 18-game Champions League slate on Wednesday, teams return to their domestic assignments this weekend. Let's head over to the English Premier League, where I've narrowed in on three best bets. Here are my favorite Premier League Matchday 24 bets.
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Premier League Matchday 24 Preview & Best Bets (2026)
(Odds courtesy of DraftKings Sportsbook)
Aston Villa (+110) vs. Brentford (+260), DRAW (+245) | O/U 2.5 (-125/-105)
Sunday morning's four-match schedule opens up with a top-10 battle between Aston Villa (14-4-5, 46 points) and Brentford (10-3-10, 33 points). The teams enter the matchday ranked third and eighth, respectively. Kick-off is set for 9:00 a.m. ET from Villa Park in Birmingham.
Brentford has dropped back-to-back games, losing to Chelsea (2-0) and Nottingham Forest (2-0), more recently. Unfortunately for the Bees, Villa Park isn't a great spot to right the ship. Aston Villa has been lights out at home this season, posting an 8-1-2 mark. They've doubled up their opponents at home, out-scoring visiting clubs 18-9.
On the other hand, Brentford hasn't fared well on the road this season, going just 3-0-8 with a -8 goal differential (12:20). Meanwhile, the Villans have won their last three games in all competitions. They easily boast the better defense, ranking higher than the visitors in goals allowed (25 vs. 32), clean sheet rate (30.4% vs. 21.7%) and save percentage (73.6% vs. 65.1%). With their home crowd behind them, I like Aston Villa to take care of business on Sunday.
Bet: Aston Villa Moneyline (+110)
Tottenham Hotspur (+250) vs. Manchester City (-140), DRAW (+310) | O/U 2.5 (-165/+130)
Sunday's slate concludes with a marquee matchup between Tottenham Hotspur (7-7-9, 28 points) and Manchester City (14-4-5, 46 points). Manchester City and Aston Villa are just four points off of first-place Arsenal's pace in the table. This match against the 14th-place Lilywhites gets underway at 11:30 a.m. ET from Tottenham Hotspur Stadium in London.
I'll lay a goal and back Manchester City on Sunday morning. For starters, the Citizens have posted the best goal differential in the Premier League at +26 (47:21). In theory, if anyone's capable of stretching out a multi-goal win, it should be Pep Guardiola's squad. The visitors have a measurable advantage offensively, as they lead the league in scoring (47 goals) compared to Tottenham Hotspur's 10th-most tallies (33).
Furthermore, I just don't know what to make of this Tottenham Hotspur team. They're having one of those wild campaigns where they look untouchable in the Champions League, but can't get out of their own way domestically. Thomas Frank's men are winless across their last five Premier League matches, registering a record of 0-3-2. Tottenham Hotspur also hasn't had any type of home-pitch advantage this season, going 2-3-6 with a -1 goal differential (13:14) in London. Considering the struggles in England for Tottenham Hotspur, I have to fade them against a top-tier squad like Manchester City.
Bet: Manchester City -1 (+120)
Sunderland (-125) vs. Burnley (+360), DRAW (+245) | O/U 2.5 (+120/-160)
In 11th place is Sunderland (8-9-6, 33 points), who is looking to rebound from a 3-1 defeat at the hands of West Ham last time out. They should have no issues taking care of lowly Burnley (3-6-14, 15 points), although it is worth noting that the Clarets have rattled off three consecutive draws. The matchday finale is slated for Monday at 3:00 p.m. ET from the Stadium of Light in Sunderland.
Burnley hasn't had anything go right this season. They come into the weekend at 3-6-14 with the second-worst goal differential (-19) in the league. Seven of those 14 defeats have come by two or more goals. The Clarets are 10 points shy of escaping relegation, and the oddsmakers have them priced at -2500 to be sent down to the English Football League Championship.
As for Sunderland, they're putting together a respectable season for their first time back in the top flight since 2016-2017. The Black Cats also have a winning record at home, where they've gone 6-5-0. That's not overpowering, but they've had enough success to the point where I'm convinced they'll beat Burnley. I expect Sunderland to outpace this abysmal Burnley defense that's 19th in goals allowed (44) and 18th in clean sheet rate (13.0%), while having allowed the most shots on target (133) this season.
Bet: Sunderland -1 (+155)
