Thunder vs. Spurs NBA Picks & Props (Tuesday)

NBA opening night continues with the Oklahoma City Thunder visiting the San Antonio Spurs on Tuesday, October 20, at 9:30 p.m. ET on NBC. San Antonio enters as a narrow 1.5-point home favorite, while the total sits at 231.5, giving bettors a closely lined Western Conference matchup to evaluate. Will the Spurs capitalize on home-court advantage, or can the Thunder open their season with a road victory? Read on for our Thunder vs. Spurs picks and predictions, betting odds and best bets.

Best NBA Picks & Predictions: Thunder vs. Spurs

Here are our top picks and predictions for Thunder vs. Spurs.

Oklahoma City Thunder at San Antonio Spurs Picks

The final game of Opening Day features the Spurs hosting the Thunder. Last season, the Spurs won four out of five regular-season games against the Thunder, then defeated Shai Gilgeous-Alexander and Co. 4-3 in the Western Conference Finals. Including the postseason, the Spurs were 4-1 in home games against the Thunder.

The only real negative for the Spurs entering this game is that the newly acquired Tobias Harris is out with a calf injury. However, I don't think his absence will have much impact on an offense that averaged 119.8 points per game last season.

And while the Thunder allowed only 107.9 points per game last season, which was the second-fewest in the NBA, the Spurs averaged 114.4 points per game against them in the regular season. They scored at least 111 points in four of those five games, reaching 116+ in three of them.

Pick: Spurs Moneyline (-135)

Oklahoma City Thunder at San Antonio Spurs Player Props

Confidence is key. San Antonio’s Dylan Harper made eight of his 14 three-point attempts in the preseason, showcasing the offseason effort he made to improve from outside the arc. The former Rutgers standout told reporters, “There's no reason for me to be hesitant; there's no reason for me to pull back.” Long-range threats are exactly what the Spurs need to pair with All-NBA talent Victor Wembanyama’s presence around the rim.

An Opening Night duel with the Thunder provides Harper with a chance to let it rain from deep. Oklahoma City is never afraid to get into a shootout. After all, it conceded the fourth-most three-pointers made per game (14.1) in 2025-26, while also giving up the most attempted three-pointers to opposing guards. Anyone in search of more bang for their buck could sprinkle on Harper to drain three or more three-pointers at +425 odds.

Dylan Harper Over 1.5 Three Pointers Made (+135)

NBA Player Prop Bet Cheat Sheet: Thunder vs. Spurs

Welcome to your ultimate resource for NBA player props & bets, where we’ve done the heavy lifting to bring you the most informed and profitable picks. By compiling data from multiple projection sources, we’ve created a robust consensus projection that serves as the foundation for our analysis. Next, we meticulously compared these projections with the prop bet odds from leading sportsbooks, ensuring you get the most accurate and advantageous NBA prop bet picks. With our comprehensive approach, you can confidently place your bets, knowing that you have the edge in the ever-competitive world of NBA player prop betting. Let’s check out the top NBA player props, bets, and picks for Thunder vs. Spurs.

What are Player Props?
Player props refer to wagers that bettors can make based on player performance in a specific game. The majority of player props are built around the most common statistical benchmarks for a specific sport, such as yards and touchdowns in football. Most player props are straight over/under plays that open at or near -110 and are adjusted based on where the money lands. Examples of basketball player prop bets include over/under bets on points, assists, rebounds, three-pointers made, blocks, or steals.

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