The opening night of the 2023 NCAA Tournament provided plenty of drama. The good news for college basketball fans is that tonight's spreads are actually smaller than last night's, so if oddsmakers are right, these games should be just as good. The 14-win Texas Southern Tigers are in action for the third consecutive year and will face the Fairleigh Dickinson Knights. They won their previous two meetings in the First Four. The Nevada Wolf Pack will play the Arizona State Sun Devils in the nightcap.
Also, take a look at our other best bets for Wednesday:

The opening night of the 2023 NCAA Tournament provided plenty of drama. The good news for college basketball fans is that tonight's spreads are actually smaller than last night's, so if oddsmakers are right, these games should be just as good. The 14-win Texas Southern Tigers are in action for the third consecutive year and will face the Fairleigh Dickinson Knights. They won their previous two meetings in the First Four. The Nevada Wolf Pack will play the Arizona State Sun Devils in the nightcap.
Also, take a look at our other best bets for Wednesday:

Best 2023 NCAA Tournament First Four PrizePicks Bets
Here are the best PrizePicks plays for Wednesday, March 15th's college basketball action.
John Walker III Over 13.5 Points
Walker is the third-leading scorer for the Tigers. He is one of four players on the team to average double digits, scoring 12.6 per game. The reason we like this play is that Walker is one of the returning players from last year's team that won in Dayton.
Walker scored 16 in that game, and he should be plenty comfortable on the court tonight. He has scored at least 13 points in three of his last four games, and in the only game he didn't, he played just five minutes because of injury. As long as he can stay out of foul trouble, unlike Pitt's Jamarius Burton last night, Walker should clear this number easily.
Darrion Williams Over 7.5 Rebounds
The Sun Devils are one of the worst teams in the country on the glass, which means that the Wolf Pack is going to feast tonight. The Sun Devils are 356th in the country in rebounds allowed per game, and they are 314th in the nation in shooting percentage. This is a great combination of statistics for the Wolf Pack rebounders.
Darrion Williams leads the Wolf Pack with 7.3 rebounds per game. He has pulled down at least seven in six of his last seven games. Against a team that can't clean up the glass, look for him to get into double digits tonight.
Frankie Collins Over 3.5 Assists
There is something fishy about this line. Nationally, the Wolf Pack is right in the middle when it comes to opponent assists per game. So, despite the Sun Devils' poor shooting, their leading assist man should be able to get close to his average this season. So why does PrizePicks have this listed as a full assist lower than his season average?
We don't know, but we're going to take the Over because Collins has been consistent this year. He is averaging 4.4 assists per game, and he had at least four assists in each game of the Pac-12 Tournament. Collins doesn't have to have a great night to hit this number. He just has to do what he has been doing. That's why we like this so much.
Round 1 Betting Picks & Predictions
South
East
West
Midwest
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