Skip to main content

Carolina Panthers vs. New York Giants Odds & Game Pick (2021)

by October 22, 2021
Sam Darnold

This Week 7 matchup features two NFC teams that are amid losing streaks. These teams have young quarterbacks that hope to bring them a championship someday, but today may not be that day. Injuries have plagued each team. Carolina will not have their star running back, while the Giants could potentially not have there’s.

Check out all of our NFL game previews and picks >>


  • Opening Line: Panthers -2.5, O/U 43
  • Current Line: Panthers -3 O/U 43
  • Last meeting: October 7, 2018 – Giants 30, Panthers 35


The Carolina Panthers started the season at 3-0 and looked like a surprise contender in the NFC. They could have benefited from a good schedule because now they come in this game have lost three straight. Last week was one of their more competitive games during the losing streak. They went toe-to-toe against the Vikings. They staged a late comeback from down 28-17 to tie the game at 28 and send it into overtime. Unfortunately, they would lose on a game-ending field goal.

The Giants are once again in a downward spiral. They are looking at another top 10 pick come April. The offense has been atrocious, ranking 27th in points scored this season. Last week showed how much they’re not ready to compete at an elite level. The NFC- powerhouse Los Angeles Rams came into East Rutherford, moved on offense, and shut down on defense with a 38-11 win.


  • Panthers are 3-1 ATS in their L4 as favorites
  • Giants are 3-9 ATS in their L12 games at home underdogs
  • Under on a 9-6 run in Panthers L13 games

Bottom Line

There’s no way to sugar-coat it; the Giants are deficient in all aspects. The Panthers are not that much better, but they’ve shown promise this year. We’ve seen Carolina play well against some bad teams this year. The Giants are as bad as it gets. Even last week showed this losing streak could be a minor hiccup. Panthers get the win, and Sam Darnold can feel like he had the best on the field at Metlife Stadium for once.

Pick: Panthers -3

Bet $10, Win $200 if Your Team Scores a TD >>

Subscribe: Apple Podcasts | Spotify | Google Podcasts | Stitcher | RadioPublic | Breaker | Castbox | Pocket Casts

Whether you’re new to sports betting or a betting pro, our How To Bet and Sports Betting Strategy and Advice pages are for you. You can get started with our 101 section — including How to Bet on Sports — or head to more advanced strategy — like 10 Tips to Become a Sharper Sports Bettor — to learn more.

Game Previews, NFL, Picks