Skip to main content

Jacksonville Jaguars vs. Los Angeles Rams Odds & Game Pick (2021)

by December 3, 2021
Matthew Stafford

We have a matchup between two teams that have a three-game losing streak. There’s still a vast difference between them as one was a preseason favorite to compete for a title while the other picked to have one of the league’s worst records.

View our Pick of the Day in the BettingPros mobile app (free!) >>


  • Opening Lines: Rams -12.5 o/u 47.5
  • Current Lines: Rams -12.5 o/u 48
  • Location: SoFi Stadium
  • Start Time: 4:05 p.m. EDT
  • TV: FOX
  • Last Meeting: October 15, 2017 —  Rams 27, Jaguars 17

It has been a tumultuous few weeks for the LA Rams. Matthew Stafford’s addition at quarterback, along with this defense, was an easy favorite to go to the championship. They continued to double-down on those chances by the mid-season additions of Von Miller and Odell Beckham. Not only have both these players struggled in their early tenure with the Rams, but the team overall has not played well. Stafford has been terrible as he’s thrown five interceptions in the last three games, including three straight with a pick-six. This spot is very familiar for the former Detroit Lions quarterback as he has thrown three pick-sixes in a season seven times. This game could be a week to right the ship with three consecutive double-digit losses because…

The Jaguars are a team that is going through growing pains. A struggling rookie quarter and a rookie coach have a lot of work to do if they want to compete in the future. This team is far from its 9-6 victory over the Bills as they have a three-game losing streak. Last week could have been a game to win when they faced an Atlanta Falcons team that has looked atrocious recently, but once again, they could not put up any offensive effort, and they could not find the end zone until the last minute of the third quarter in the 21-14 loss.

Check out all of our NFL game previews and picks for the week >>


  • As an underdog, the under is 10-1  in the Jaguars’ last 11 games.
  • The Jaguars are 9-11 against the spread in their last 20 games.
  • The under is 13-5 in the Rams’ last 18 home games.
  • The Rams are 11-7 straight in games they are favorited.


If the Rams can’t come away with a win here, then it’s time not just time to hit the panic button but smash it. They are by far better in every facet of the game than Jacksonville, and they should get the home victory. The Jaguars are 24th in interceptions; Stafford should be better at holding on to the ball.

Pick: Rams -12.5

Bet $10, Win $200 if Your Team Scores a TD >>

Subscribe: Apple Podcasts | Spotify | Google Podcasts | Stitcher | RadioPublic | Breaker | Castbox | Pocket Casts

Whether you’re new to sports betting or a betting pro, our How To Bet and Sports Betting Strategy and Advice pages are for you. You can get started with our 101 section — including How to Bet on Sports — or head to more advanced strategy — like 10 Tips to Become a Sharper Sports Bettor — to learn more.

Game Previews, NFL, Picks