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Video: NFL Week 16 Early Best Bets, Odds, Picks & Predictions (2022)

by December 20, 2022

Joe Pisapia sits down with Pat Fitzmaurice and Matt Freedman to look ahead at the Week 16 NFL slate, break down the matchups, and analyze how they think the market will move by game day.


Los Angeles Rams vs. Green Bay Packers – 0:00:47
Jacksonville Jaguars vs. New York Jets – 0:04:05
New York Football Giants vs. Minnesota Vikings – 0:08:13
Baltimore Ravens vs. Atlanta Falcons – 0:12:55
Detroit Lions vs. Carolina Panthers – 0:16:20
Buffalo Bills vs. Chicago Bears – 0:20:27
New Orleans Saints vs. Cleveland Browns – 0:23:38
Kansas City Chiefs vs. Seattle Seahawks – 0:28:10
Cincinnati Bengals vs. New England Patriots – 0:30:33
Houston Texans vs. Tennessee Titans – 0:36:10
San Francisco 49ers vs. Washington Commanders – 0:38:22
Philadelphia Eagles vs. Dallas Cowboys – 0:42:19
Las Vegas Raiders vs. Pittsburgh Steelers – 0:45:40
Green Bay Packers vs. Miami Dolphins – 0:47:35
Los Angeles Rams vs. Denver Broncos – 0:48:33
Arizona Cardinals vs. Tampa Bay Buccaneers – 0:49:58
Indianapolis Colts vs. Los Angeles Chargers – 0:51:43
Favorite Bets of the Week – 0:53:50

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What is Betting Against the Spread?

Betting “against the spread” refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

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NFL, Picks