Skip to main content Skip to navigation Skip to footer

NFL Week 18 Odds & Picks: Rams vs. 49ers (Sunday)

Rams vs. 49ers: NFL Same Game Parlays Odds & Picks (Week 18)

Gear up for another weekend of NFL action! Make sure to check in with BettingPros throughout the year for top picks and predictions for each and every NFL game. Our writers dive into their favorite picks and predictions for every remaining game on this Sunday’s NFL slate. Below we check out Rams vs. 49ers.

Go premium to view top prop bets based on Cover Probability, Expected Value & Star Rating >>

DraftKings Sportsbook Offer

NFL Odds, Picks & Predictions: Sunday

Rams vs. 49ers

We're getting a matchup between Sam Darnold and Carson Wentz in Week 18. Who would've thought? Both teams will have key starters on the bench for this matchup. But overall, Darnold's opportunity at quarterback is greater. Wentz's career is almost over. However, Darnold still wants to be a No. 1 quarterback at just 26 years old. This is a big one for Darnold, who likely has more depth on his side than Wentz does. I know Wentz is just 31 years old, but his time in the NFL is pretty much finished. That's why it took him so long to even land on a roster this year. Based on the depth of the Niners and Rams, I'll rock with San Francisco at -4.

Pick: 49ers -4

-Jason Radowitz


Subscribe: Apple Podcasts | Spotify | Google PodcastsRadioPublic | Breaker | Castbox | Pocket Casts

Whether you're new to sports betting or a betting pro, our Sports Betting Strategy and Advice page is for you. You can get started with our 101 section - including 10 Sports Betting Tips for Beginners - or head to more advanced strategy - like Key Numbers When Betting Against the Spread - to learn more.