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NFL Week 8 Player Prop Bet Odds, Picks & Predictions: 49ers vs. Rams (2022)

The 49ers have won two in a row to get back above .500. However, in their last four games, they are just 1-3 against the spread, and they failed to cover at home as 7.5-point favorites on Sunday night. The Cardinals took care of business against the Rams even though Kyler Murray was out with a hamstring injury. Yet, bettors do not seem impressed since the win came with Matthew Stafford out. Before that game, the Cardinals had lost four of their previous five. This line seems like it was made assuming that Murray will be out again this week. However, even if he is, Colt McCoy was solid in the Cardinals’ win, completing 26 of 37 passes for 238 yards and one touchdown. Therefore, no matter who is under the center, look for this line to drop below the key number. Current Line: 49ers -7.5 Predicted Final Line: 49ers -6.5

We compiled several projection sources to come up with consensus projections. We then compared these projections to the prop bet odds from the sportsbooks to give you the best prop bet picks. View the best player prop bets for this week’s slate with our NFL Prop Bet Cheat Sheet. Check out our top player prop bet odds, picks, and predictions for 49ers vs. Rams.

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NFL Player Prop Bet Rankings, Odds, Picks & Predictions: 49ers vs. Rams

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

View 5 star bets and historical prop performance by player with our Prop Bet Analyzer >>


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