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NFL Week Anytime Touchdown Scorers Picks & Predictions (2025)

NFL Monday Night Football First TD Scorers: Vikings vs. Rams (Wild Card)

We took shots on some longer odds anytime TD scorers in Week 5, and got to the window with Commanders RB Jacory Croskey-Merritt (+260), Seahawks WR Tory Horton (+360), and Eagles TE Dallas Goedert (+350). I've got some of those longer odds plays this week, mixed in with some guys around the 2/1 odds range. I absolutely love the board this week, which features some high-volume Red Zone options with really advantageous matchups against the opposing defense. Enough data is available to really dig into this market as we enter the 1/3 mark of the NFL season, so let's keep things rolling and cash some more tickets here with our top Week 6 anytime touchdown scorers picks.

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Best NFL Week 6 Anytime Touchdown Scorers Picks 

(Odds courtesy of FanDuel Sportsbook)

Cleveland Browns @ Pittsburgh Steelers

David Njoku (TE – CLE) | +470

Rookie QB Dillon Gabriel gave the Browns offense some much-needed life last Sunday, tossing for 190 yards and 2 TDs in his debut and nearly leading Cleveland to an upset victory over the Vikings in London. TE David Njoku was far and away Gabriel's favorite target in his first start, leading the Browns in targets (9), receptions (6) and receiving yards (67). He shared the end zone with fellow TE Harold Fannin Jr., but Fannin recorded just 13 yards on 4 receptions. TEs have had success against the Steelers in the early going, as Pittsburgh ranks bottom 10 in terms of fantasy points allowed to the TE position and has conceded the 5th-most receiving TDs to TEs so far. The Steelers also rank 3rd-worst in terms of passing yards conceded per game in general. Both Cleveland TEs have the same amount of Red Zone targets (3), and targets inside the 10-yard line (1) and are sitting at nearly identical odds to score in Week 6, so I'll go with Njoku as the guy who seems to be the go-to option for Gabriel as he gets acclimated to the league.


Los Angeles Chargers @ Miami Dolphins

Keenan Allen (WR – LAC) | +170

It's a tough choice between the Chargers’ WR trio, who all seem to have nearly identical odds to score on a weekly basis, regarding who might find the end zone. This week, I'm going with Keenan Allen, who currently ranks 6th in the entire NFL in terms of Red Zone targets (7), which is good for 41% of all targets to Chargers pass catchers. Those numbers hold up inside the 10-yard line as well, as his 5 targets inside the 10 rank 5th in the NFL and comprise 50% of all targets to Chargers pass catchers. The fact that the Chargers RB depth has been severely impacted with injuries to Najee Harris and Omarion Hampton also increases the likelihood for Allen to get looks around the goal line. The Dolphins defense he'll be up against is certainly not a stalwart, surrendering nearly 30 PPG and T-5th in terms of TDs allowed to opposing WRs. With Quentin Johnston serving as the deep threat and Ladd McConkey doing most of his work in the middle of the field in between the 20 yard lines, I'll take Keenan Allen to find the end zone as the definitive high-target option around the end zone.


New England Patriots @ New Orleans Saints

Stefon Diggs (WR – NE) | +170

After a slow start to the season, Patriots WR Stefon Diggs absolutely exploded on Sunday Night Football, going for 146 yards on 10 receptions on the road against the NFL's 2nd-ranked defense in terms of passing yards allowed per game. That performance came on the heels of another 100+ yard performance against Carolina the week before, showing that things are really starting to click between Diggs and Drake Maye. Things will seemingly come even easier this week, indoors against a Saints defense that ranks bottom 10 in terms of points allowed at 27 PPG and TDs allowed to opposing WRs. I'm admittedly buying a little bit high on Diggs in this spot, who has seen his odds drop compared to where they were in weeks 1-3, but I think he's absolutely due to find the end zone for the first time this season in a really advantageous matchup against a Saints defense that doesn't offer much resistance.


Los Angeles Rams @ Baltimore Ravens

Kyren Williams (RB -LAR) | 2+ TDs (+350)

Ravens games have quickly gone from must-see TV to get this off my TV, as they currently sit at 1-4 with Lamar Jackson set to miss a 2nd straight game. Baltimore ranks dead-last in points allowed at 35+ PPG, 2nd-worst in terms of both total yards and passing yards allowed per game and 4th-worst in terms of rushing yards allowed per game. On average, they surrender the 3rd-most fantasy points per game to opposing RBs, and the 8 total TDs allowed to opposing RBs is the 2nd-most in the NFL. I'm playing right into that game script as my pick for this game, as I'm going with Rams RB Kyren Williams to record 2+ TDs on Sunday. Williams is no stranger to racking up multi-TD performances, with 9 such games since the 2023 season. His 24 Red Zone rushing attempts put him in the top-10 of all ball carriers, and his 3 TDs on 5 Red Zone receiving targets prove that he's a threat to score on a reception as well. In fact, of those 9 career multi-TD games, Williams recorded a receiving TD in 4 of them and had 2 games of 2+ receiving TDs. Williams is one of the few true workhorse backs around in the NFL, and he should get ample opportunities to score in what should be an extremely favorable game script against one of the league's most vulnerable defenses. Add in the fact that Cooper Rush will likely gift the Rams an extra possession or two with turnovers, and I like this play even more.


Arizona Cardinals @ Indianapolis Colts

Daniel Jones (QB – IND) | +200

We cashed on Daniel Jones to score in Week 1, and after a few monster performances from Colts RB Jonathan Taylor, I think the value is back on Jones to find paydirt in Week 6. Despite Taylor's success, Jones is still responsible for roughly 1/3 and 1/4 of all Colts Red Zone carries and carries inside the 10-yard line, respectively. While the Cardinals have yet to concede a rushing TD to the QB position, Bryce Young is the only real mobile QB they have faced this season, and his rushing style is really not all that comparable at all to the much more physical style of the bigger-bodied Daniel Jones. With the status of Kyler Murray up in the air, it's not much of a stretch at all to say that the Colts will likely find themselves in another favorable, rush-heavy game script with plenty of scoring opportunities. As Jonathan Taylor's odds to score are currently in excess of -200, I think this is a great opportunity to back Jones (who recorded 3 rushing TDs in the first two weeks) to get back into the end zone.


Seattle Seahawks @ Jacksonville Jaguars

AJ Barner (TE – SEA) | +300

It's crazy to suggest, but it feels like Seahawks TE AJ Barner is quietly coming off a 2 TD performance due to the show that WR Jaxon Smith-Njigba put on, and Rookie WR Tory Horton finding the end zone again. Barner is not a high-volume target, receiving more than 3 targets only 1 time this season, but his targets come where it matters the most. Despite all the rushing and receiving options on this Seattle offense, Barner's 5 Red Zone targets and 3 targets within the 10-yard line definitively lead all Seattle offensive personnel. Barner has 4 TDs in 5 games this season, and the fact that he doesn't exactly make splash plays on a weekly basis is keeping these odds inflated. I love him to find the end zone for a third straight week as the high-volume red zone target in this offense in a game that figures to sneakily be one of the best ones on the board in Week 6.


Dallas Cowboys @ Carolina Panthers

Tetairoa McMillan (WR – CAR) | +145

Panthers Rookie WR Tetairoa McMillan has been extremely consistent to begin his NFL career, with 3-6 receptions on 8-10 targets for 48-100 yards in every single game. Unfortunately, he's also been consistent in the fact that he has not yet recorded his 1st NFL TD. That should change this week, as he and the Panthers have an A+ matchup at home against the Dallas Cowboys. Dallas has conceded the most fantasy points per game to opposing WRs, and the 10 TDs given up to opposing wideouts also leads the NFL. They are dead-last in the league in passing yards allowed per game, and rank 4th-worst with 30+ points allowed per game. Tetairoa has had some opportunities, with 5 Red Zone targets this season, but it just hasn't been converted into points yet. I know I might sound like a broken record, as Tetairoa has been my anytime TD pick in a few Panthers games so far, but it's hard to believe that he doesn't finally break through this week in a great home spot against an absolutely atrocious Dallas defense.


Tennessee Titans @ Las Vegas Raiders

Elic Ayomanor (WR -TEN) | +380

Titans games and Raiders games tend to be the most difficult ones for me to evaluate on a weekly basis, so I'm going with Titans Rookie WR Elic Ayomanor as ol' reliable here in Week 6. Ayomanor has been my most profitable player of these articles so far this year, cashing tickets around +400 on multiple occasions this season. Ayomanor and the Titans have a favorable matchup this week against a Raiders defense that ranks bottom-5 in both fantasy points and TDs allowed to opposing WRs. Overall, they rank bottom 10 in points allowed per game and sit in the bottom half of the league in passing yards allowed per game. Ayomanor has received 2/3 of all Red Zone targets to Titans pass catchers and 3/4 of all Titans targets inside the 10-yard line, showing that QB Cam Ward definitely has trust and is building a rapport with his rookie counterpart. In a favorable indoor matchup against the Raiders in what could be a winnable game, give me Ayomanor to find paydirt again at close to 4/1 odds.


San Francisco 49ers @ Tampa Bay Buccaneers

Jake Tonges (TE – SF) | +260

49ers TE Jake Tonges has made a name for himself in the absence of All-Pro TE George Kittle, with 3 TDs on the young season. He was an especially large part of the offense last week, reeling in 7 receptions on 11 targets for 41 yards and a TD. Tonges looks to have a pretty favorable matchup this week, against a Buccaneers defense that ranks bottom-10 in points allowed per game overall, as well as bottom-10 in fantasy points allowed to opposing TEs. Most importantly for this play, they've also given up T-2nd most receiving TDs to opposing TEs on the season. Tonges has caught all 3 of his Red Zone targets for 2 TDs, and he figures to be a focal point in the offense again as WR Ricky Pearsall is set to miss another game. Give me Tonges to stay hot and find the end zone for a 3rd straight week as a reliable Red Zone target for QB Mac Jones.


Cincinnati Bengals @ Green Bay Packers

Tucker Kraft (TE – GB) | +180

Packers TE Tucker Kraft has cooled off a bit after finding the end zone in the first 2 weeks of the season, but I find good reason to believe he finds paydirt again this week. The Bengals are yet again one of the league's worst defenses, ranking bottom-3 in total yards allowed per game, passing yards allowed per game and points conceded per game. Specifically, the Bengals surrender the most fantasy points to TEs of any team in the league, and they're T-2nd worst in terms of TDs allowed to opposing TEs. Kraft ranks just behind WR Romeo Doubs in terms of Red Zone targets to Packers pass catchers, as his 5 targets comprise 25% of the target share in the Packers offense. His target share inside the 10-yard line also totals 20% of all targets to Green Bay offensive personnel. The matchup is perfect, the odds are playable, and I love Kraft to add another one to the TD column in Week 6.


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