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Buffalo Bills vs. Kansas City Chiefs Odds & Game Pick (2022)

by January 20, 2022
Bengals vs. Bills: 2023 NFL AFC Divisional Round Picks & Predictions (Sunday)

A week after hanging 47 points on their division foe Patriots in a rout that was never close, the Bills now head to Kansas City where the competition will likely be much stiffer. Ditto for the Chiefs, who steamrolled the Steelers last week for the second time in less than a month.

Let’s take a closer look at according to bookmakers, will be the closest game on the board this weekend.

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  • Opening Line: Chiefs -2, O/U 55
  • Current Line: Chiefs -1.5, O/U 54
  • Last meeting: October 10, 2021, Bills 38, Chiefs 20


The Chiefs finished the regular season as one of the hottest teams in the league, winning nine of their final 10 games on their way to the #2 seed in the AFC. While they’ve gotten better down the stretch, the defense has been a concern for this Chiefs team as they finished the regular season allowing 368.9 yards per game, good for 27th in the league.

For the Bills, however, the defense has been of no concern. Ranking #1 in the league in total yards, passing yards, and total points allowed, the Bills are top to bottom the best defensive team in the NFL this season. More trouble for the Chiefs, the Bills are also one of the best offensive teams in the league, averaging more than 28 points per game in the regular season led by a passing and rushing attack both in the top 10.

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  • Over is 8-0 in Bills L8 as an underdog
  • Bills 4-0-1 ATS in L5 games
  • Over 6-0 in Chiefs L6 games

Bottom Line

While it’s tough to bet against Mahomes and company, especially at home, all signs I typically look for lead to the Bills in this one. Coming into this one with the confidence of beating their once big brother Patriots twice in a month’s span, both decisively, I like for the Bills to win a close game late in Kansas City Sunday night.

Pick: Bills ML +115

Bet $10, Win $200 if the Chiefs or Bills Team Scores a TD >>

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Johnny is a featured writer at BettingPros. For more from Johnny, check out his archive and follow him @JohnnyCovers.

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