No. 6 Indiana heads to Michigan Stadium on Saturday, October 24, for a Big Ten showdown with Michigan at noon ET on Fox. The Hoosiers enter as 7.5-point road favorites, while the total sits at 42.5. Can Indiana clear a spread of more than a touchdown in Ann Arbor, or will the Wolverines deliver a home upset? Our Indiana vs. Michigan picks and predictions examine the Week 8 college football odds, key matchup factors and best bets.
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College Football Week 8 Bets & Picks: Indiana vs. Michigan
(Odds and lines via BettingPros’ consensus betting information)
Week 7 of the 2026 college football season featured some incredible performances. Auburn kicker Alex McPherson drilled a 34-yard field goal as time expired to upset No. 1 Georgia 27-24. Tennessee running back DeSean Bishop racked up 175 total yards and two touchdowns in a 26-10 victory over Alabama. The focus now shifts to a Week 8 slate packed with intriguing storylines and ranked programs in action. Here’s a look at our favorite college football picks for Saturday’s game Indiana vs. Michigan.
Indiana vs. Michigan Picks
This is one of the larger edges shown toward a favorite this week, and Michigan's issues lie with its offense. The Wolverines have the No. 1 pass-blocking offensive line according to PFF, but their passing grade ranks 107th, leading to a switch to Tommy Carr as the starter for this game. The offensive line has also paved the way well in the run game, earning the 23rd-highest run-blocking grade. However, Michigan's rushing grade ranks 109th, and the Wolverines are 84th in rushing yards per game (147.7).
Carr might improve what has been the 106th-ranked scoring offense (22.7 PPG), but asking him to do so against Indiana in his first start might be a bit too much. The Hoosiers face an uphill battle against a strong Michigan defense, but the highest-scoring offense the Wolverines have faced this season is Iowa (61st, 31 PPG).
Indiana is a miserable 1-6 ATS this season. The Hoosiers' first three ATS losses came when they failed to cover spreads of at least 40.5 points. Their other ATS losses included the windy game at Nebraska, the game in which Nick Marsh stepped out of bounds, and a truly disappointing result against Northwestern at home. The Hoosiers' defense remains stout, with the 23 points allowed to Northwestern still standing as its season high. QB Josh Hoover isn't a Heisman contender, but he's turned the ball over only once, and Indiana has just three turnovers as a team (tied for fifth).
Indiana might struggle to move the ball and score, but Michigan is in a much worse spot offensively, even at home. Lay the points and expect a better day for Indiana.
Pick: Indiana (-7)
