The New York Giants and Los Angeles Rams close out Week 2 on Monday Night Football, and the matchup offers several intriguing anytime touchdown scorer bets. Before placing your wagers, check out our top Giants-Rams touchdown picks based on the latest odds, player usage and matchup data.
BettingPros' five-star anytime touchdown picks opened the season with a 10-5 record, producing a 66.7% win rate, 32.4% ROI and 4.9 units of profit. With that strong Week 1 performance in mind, here are our best anytime touchdown scorer picks for Giants vs. Rams.
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NFL Monday Night Football Anytime TD Scorers: Giants vs. Rams
Monday night, the New York Giants face the Los Angeles Rams. Millions of dollars will be bet on this game. But which touchdown prop bets should you take? Let's dive into our picks for anytime touchdown scorers.
Odds via DraftKings Sportsbook
Isaiah Likely (TE – NYG)
One of the less talked-about big-name moves in free agency this offseason was Likely joining the Giants. The former Coastal Carolina star was outstanding in his New York debut, totaling eight receptions for 78 receiving yards and two touchdowns, leading the team in every category. Furthermore, his eight targets were second on the team behind Malik Nabers' nine. More importantly, Likely should see another high-target game on Monday night with Aaron Donald making his season debut.
Last week, the veteran had an aDOT of 8.3, the lowest of any Giants player with at least 14 routes run. Meanwhile, the Rams surrendered seven receiving touchdowns to tight ends in 2025, the 13th-most in the NFL. More importantly, they gave up three receiving touchdowns to the San Francisco 49ers last week, with two coming to pass catchers lined up out wide. One of Likely's two touchdowns last week came when he was lined up on the outside.
Kyren Williams (RB – LAR)
While he isn't the flashiest or most explosive runner, Williams does an excellent job of finding the end zone. The former Notre Dame star had at least 10 rushing touchdowns and 13 offensive scores in three consecutive seasons. Furthermore, the veteran had the first and only Los Angeles touchdown in the Week 1 loss to San Francisco. More importantly, Williams has an appealing matchup on Monday night after the Giants struggled to contain Javonte Williams last week.
New York won their Week 1 matchup against the Dallas Cowboys but had no answer for the veteran running back. Williams had 17 touches for 72 scrimmage yards and two touchdowns against the Giants, scoring on the ground and in the passing game. Meanwhile, the last time Los Angeles faced New York, the former Notre Dame star had three rushing touchdowns. More aggressive bettors should back Williams to score an anytime touchdown in the first quarter at +370.
Davante Adams (WR – LAR)
Unfortunately, Puka Nacua missed the final two days of practice last week with a hip injury. The Rams listed the superstar as questionable for Monday's contest. Even if Nacua plays, Adams will likely see an increase in targets. Regardless of whether Nacua plays, the future Hall of Famer is an excellent bet to find the end zone. Last year, Adams led the NFL with 14 receiving touchdowns despite missing the final three games with a hamstring injury.
Furthermore, Jordan Whittington is doubtful to play in Week 2 because of a quad injury, leaving the depth at wide receiver behind Adams extremely thin. Meanwhile, the Giants struggled to keep CeeDee Lamb out of the end zone last week, as the former Oklahoma star had a team-high eight targets and scored a one-yard touchdown in the second quarter. While Adams has limited experience facing New York, the veteran has three receiving touchdowns in three career matchups.
Malik Nabers (WR – NYG)
Nabers almost didn't play in Week 1. However, the superstar suited up for the first time since tearing his ACL last year. Despite not playing in the preseason, Nabers was productive, totaling six receptions on nine targets for 69 receiving yards. While he didn't find the end zone, the superstar had a team-high nine targets, earning a 31% target share. More importantly, Nabers ran a team-high 82.6% of his routes in Week 1 lined up out wide.
Meanwhile, the Rams added two big-name cornerbacks in the offseason. Yet, they surrendered three receiving touchdowns to the 49ers' wide receiver unit last week. Two of those three receiving touchdowns went to wide receivers lined up on the outside, including Demarcus Robinson. More aggressive bettors should back Nabers to score two or more touchdowns at +1400. The former LSU star has scored at least two touchdowns in 15% of the games in his career.
Mike Fanelli is a featured writer at BettingPros. For more from Mike, check out his archive and follow him @Mike_NFL2.

