We've reached the halfway point of the 2025-26 English Premier League (EPL) campaign. Arsenal (45 points) just extended its first-place lead over Manchester City (41) and Aston Villa (39) with a 4-1 win over the latter in their mid-week clash. The Gunners, per DraftKings Sportsbook, are -200 favorites to secure their first EPL title since 2003-04.
The Premier League action continues this weekend, with all 20 teams gearing up to take the pitch. Below, I've listed my top three Premier League Matchday 20 bets.
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Premier League Matchday 20 Preview & Best Bets (2025)
(Odds courtesy of DraftKings Sportsbook)
Aston Villa (-125) vs. Nottingham Forest (+350), DRAW (+270) | O/U 2.5 (-125/+100)
Third-place Aston Villa (12-3-4) had its 11-match all-league winning streak snapped on Tuesday when they were hammered 4-1 on the road against Arsenal. They'll return home on Saturday morning to host 17th-place Nottingham Forest (5-3-11), who are only four points above the relegation line. Kick-off is scheduled for 7:30 a.m. ET from Villa Park in Birmingham.
Aston Villa may have lost its 11-match winning streak, but there is another streak that's still intact. That's Unai Emery's 10-game heater at Villa Park. The third-place club has been lights out at home in the Premier League this season, going 7-1-1 with a +8 goal differential (15:7). They'll host a Nottingham Forest side that's just 2-2-5 on the road, owning a -7 goal differential (6:13).
I'm shocked to see Aston Villa as such a small favorite. I figured it would be closer to the -175 range, so I'll gladly back them to rebound from the 4-1 shellacking at the hands of Arsenal. The Villans are a respectable ninth in clean sheet percentage (26.3%) this season, so they should have no issue shutting down the Tricky Trees, who have only 18 goals (19th) in 19 matches.
Bet: Aston Villa Moneyline (-125)
Wolverhampton (+150) vs. West Ham (+185), DRAW (+235) | O/U 2.5 (+100/-130)
Right after the Aston Villa versus Nottingham Forest game on Saturday, we have a bottom-of-the-table thriller between Wolverhampton and West Ham. Wolverhampton Wanderers (0-3-16) are still searching for their first win of the season, while the visiting Irons (3-5-11) haven't been much better, sitting just below the relegation line in 18th place. Kick-off is slated for 10:00 a.m. ET from Molineux Stadium in Wolverhampton.
This is the best opportunity on the schedule for the fine folks of Wolverhampton to witness their team earn a win. Even though it has been tough sledding for the Wolves, I just cannot pass up on a +150 payout for them to notch their first win of the year.
They'll host a West Ham side that hasn't fared well on the road, going just 1-4-4 with a -6 goal differential (9:15). Their expected goals difference per 90 minutes (xGD/90) on the road is -0.78, which sits only above Burnley's last-place mark of -1.35. Overall, this season, West Ham actually has a slightly worse xGD/90 (-0.64) compared to Wolverhampton (-0.55). In terms of recent form, the visitors are winless across their last eight matches (0-4-4). Wolverhampton turned in a surprising 1-1 draw against Manchester United last time out, and I'm willing to take a flier on them in this spot.
Bet: Wolves Moneyline (+150)
Manchester City (-160) vs. Chelsea (+370), DRAW (+360) | O/U 3.5 (+125/-155)
Matchday 20 wraps up on Sunday with a heavyweight clash in Manchester, as second-place Manchester City (13-2-4) takes on fifth-place Chelsea (8-6-5). This contest gets underway at 12:30 p.m. ET from Etihad Stadium in Manchester.
Things are a bit chaotic for Chelsea at the moment, as manager Enzo Maresca just departed from the club by mutual consent. This management move comes after a rough 1-4-2 Premier League stretch. The Blues have conceded multiple goals in three straight matches, and their expected goals allowed (xGA) of 26.2 is now a middle-of-the-road 10th in the table.
The Maresca exit has made way for Calum McFarlane to take the reins in an interim role. He draws an unfavorable matchup against a Manchester City side that's heating up, going 8-1-0 in their last nine matches in all leagues. To make matters worse for the Blues, they've also been pummelled in the head-to-head department, going winless (0-2-9) in their last 11 meetings with the Citizens.
Manchester City, who's an excellent 8-0-1 with a +19 goal differential (25:6) at home this year, should cruise past a floundering Chelsea on Sunday afternoon. I'll lay the goal at -105 in this marquee matchup.
Bet: Manchester City -1 (-105)
