Premier League Matchday 28 Odds, Picks & Prediction (2024)

The Premier League title race is heating up, and we have a few pivotal matches on the schedule this weekend.

The marquee matchup features Liverpool hosting Manchester City, while Aston Villa and Tottenham will also square off as they battle for top-four positioning in the table. I'll dive into each of those contests, as well as Arsenal's match against Brentford.

Here are my favorite bets for Matchday 28 in England!

Get instant alerts when a line reaches your target via the BettingPros App >>

Premier League Matchday 28 Odds, Picks & Prediction

(Odds courtesy of DraftKings Sportsbook)

Arsenal (-425) vs. Brentford (+1000), DRAW (+600) | O/U 3.5 (+120/-145)

Mikel Arteta and his squad are on fire right now, and they're looking to build on a 6-0 road beatdown of Sheffield last weekend. They'll return home to host Brentford, who rose to 15th in the table (26 points) after securing a 2-2 road draw against Chelsea. This contest is the Saturday nightcap, which kicks off at 12:30 p.m. ET from Emirates Stadium in London, England.

I'm locking in the over in this Saturday clash, but I will play it conservatively and take the total down to a flat 3.0 goals. Mainly, I want to be cautious since the Gunners have a huge Champions League match on Tuesday, where they must erase a 1-0 deficit at home against Porto. Perhaps Mikel Arteta gets a comfortable lead on Saturday and opts to rest his starters ahead of the second UCL leg.

Other than that, this match has all the indicators of a barnburner. Arsenal's offense has been on a tear on the domestic front, averaging an insane 4.4 goals per game over their current 7-0-0 stretch in the PL. Meanwhile, the Bees' defense is slowly becoming one of the worst in the league, sitting at 17th in overall defense (50 goals allowed). Offensively, with the return of Ivan Toney, who already has four goals in eight matches back, this Brentford offense shouldn't be taken lightly. Let's sit back and watch these dynamic offenses go to work.

Bet: Over 3.0 (-150)

Aston Villa (+140) vs. Tottenham Hotspur (+165), DRAW (+300) | O/U 3.5 (-120/-105)

We have a couple of heavyweight matches on Sunday morning, and the action gets underway with this tie between Aston Villa and Tottenham. The Villans currently reside in fourth in the table (55 points), while the Spurs are right behind them in fifth (50 points). Kickoff is set for 9:00 a.m. ET from Villa Park in Birmingham, England.

Like the Arsenal/Brentford game, I think this one also turns into an absolute goal-fest. Let's start with Aston Villa's home form, where they're 10-1-2 at Villa Park this season. Their offense has been very impressive, netting the second-most home goals (Liverpool 37) this term with 36. That's 2.8 goals per match at home. Unai Emery's men have been playing in high-scoring affairs recently, going 3-0-0 in their last three PL matches, out-scoring the opposition 9-5.

Conversely, Tottenham is one of the better road teams this season. They've managed 26 away goals over 12 road contests (2.2 GPG). Regarding overall offense, the Spurs are sixth, where they've scored 55 goals this season. Son Heung-Min (13 PL goals) and Richarlison (10 PL goals) are at the forefront of this high-paced attack. I think the duo will do enough to help push this match over the elevated total.

Bet: Over 3.5 (-120)

Liverpool (+195) vs. Manchester City (+130), DRAW (+275) | O/U 3.5 (+130/-165)

Sunday's action concludes with a huge match between banged-up Liverpool and red-hot, Treble-winning Manchester City. The Reds (63 points) hold a one-point edge at the top of the table over the Citizens (62 points). Kickoff is scheduled for 11:45 a.m. ET from Anfield in Liverpool, England.

Let's start with Liverpool's injury report, where it's confirmed that both Alisson Becker (muscle) and Trent Alexander-Arnold (knee) will be out. Alexander-Arnold scored an equalizer in the 1-1 draw at the Etihad back in November. However, there's good news out of Liverpool, as Mohamed Salah (15 PL goals) returned to training this week. With Salah and the upward-trending Darwin Nunez (10 PL goals) bolstering the attack, I think it will give the Reds a chance to pull out a draw on Sunday.

Liverpool plays at the fortress known as Anfield. Jurgen Klopp's side leads the league in home points this term, sitting at 11-2-0 (35 points). I think that unbeaten streak stays alive on Sunday, but I'm not sure they'll have enough firepower to pull off the outright victory. Ultimately, this match is a toss-up, but I want some action on it, so I'll sprinkle a small bit of my bankroll on the +275 draw. Interestingly, the draw has cashed in four of the last seven Premier League meetings between the two clubs.

Bet: Draw (+275)

Make sure to check out our other best bets for Friday: