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49ers vs. Commanders: NFL Week 17 Odds & Picks (2023)

8 49ers Sports Betting Trends to Know for Super Bowl LVIII

Gear up for another weekend of NFL action! Make sure to check in with BettingPros throughout the year for top picks and predictions for each and every NFL game. Our writers dive into their favorite picks for this Sunday’s NFL slate. Below we explore 49ers vs. Commanders.

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49ers vs. Commanders

The 49ers got slapped in the face on their home field with a 33-19 loss to the Ravens. Looking at the stats, San Fransisco out-gained them by 114 yards, but the five turnovers are what cost them. Now they go from facing a Baltimore team whose +10 turnover ratio is the best to Washington's -10, which is the worst. The Commanders made a shocking decision and have elected to keep Jacoby Brissett as the quarterback over Sam Howell, although he is listed on the injury report and is questionable. The Commanders have far bigger problems than at quarterback, mainly the defense that's allowing the most yards and points per game. The 49ers have been able to smash the bad teams throughout the season, and Washington is continuing to spiral.

Pick: 49ers -13.5

-John Supowitz