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Video: College Football Week 2 Line Movement & Early Picks (2025)

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Don’t let the semester pass you by without getting in on the CFB betting scene! Join Seth Woolcock and Scott Bogman for their 2025 College Football Week 2 early picks and line movement predictions.

Can the #22 Iowa State Cyclones (-3) get another win over their in-state rival, the Iowa Hawkeyes? Do the #21 Ole Miss Rebels (-10) get their revenge on the Kentucky Wildcats? Plus, will the #18 Oklahoma Sooners (-4.5) prove their worth by defending home turf against the #14 Michigan Wolverines?

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  • Introduction – 0:00:00
  • College Football Week 1 Recap – 0:02:28
  • College Football Week 1 Betting Risers & Fallers – 0:03:12
  • College Football Week 1 Takeaways – 0:06:24
  • Baylor Bears vs. #16 SMU Broncos – 0:09:28
  • Iowa Hawkeyes vs. #22 Iowa State Cyclones – 0:12:23
  • #12 Illinois Fighting Illini vs. Duke Blue Devils – 0:15:45
  • #21 Ole Miss Rebels vs. Kentucky Wildcats – 0:18:21
  • Kansas Jayhawks vs. Missouri Tigers – 0:24:11
  • South Florida vs. #15 Florida Gators – 0:27:39
  • #14 Michigan Wolverines vs. #18 Oklahoma Sooners – 0:31:51
  • Vanderbilt Commodores vs. Virginia Tech Hokies – 0:36:26
  • #11 Arizona State vs. Mississippi State Bulldogs – 0:39:51
  • Virginia Cavaliers vs. North Carolina State Wolfpack – 0:45:09
  • Outro – 0:49:14

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What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

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