Auburn vs. Ole Miss College Football Week 9 Picks (Saturday)

Auburn travels to Oxford to face No. 12 Ole Miss on Saturday, October 31, with kickoff set for 12:45 p.m. ET on SEC Network. The Rebels enter as 11.5-point home favorites at Vaught-Hemingway Stadium, while the total sits at 57.5. Ole Miss will need a win by at least 12 points to cover, while Auburn looks to keep things competitive and threaten an upset. Our Auburn vs. Ole Miss picks and predictions break down the Week 9 college football odds, key matchup factors and best bets.

Get instant alerts when a line reaches your target via the BettingPros App >>

College Football Week 9 Best Bets & Picks: Auburn vs. Ole Miss

We’re firmly in the back half of the 2026 college football regular season, and there’s never been more parity in the sport. In Week 8, we saw No. 2 BYU fall to unranked UCF in 20T, No. 8 Texas Tech lost to unranked Cincinnati, No. 11 Tennessee blew a late lead against unranked South Carolina, and No. 15 Iowa and No. 16 USC both lost to unranked Big 10 opponents on the road.

Even without a bunch of head-to-head matchups between top 25-ranked opponents in Week 9, we now know that no opponent can be taken for granted. Let’s take a look at some of my top picks of the week.

Auburn vs. Ole Miss (12)

Auburn and Ole Miss are both coming off losses. However, the Tigers’ 38-17 home loss to No. 15 LSU has led to them moving from +10.5 to +11.5 in point spread betting markets against the Rebels in Week 9.

There’s value on head coach Alex Golesh’s program, which has had a volatile campaign under their first-year head coach. Auburn’s season-defining win over previously No. 1 Georgia didn’t transfer momentum, instead, losing by 21 points to LSU at home.

Ole Miss fell into a huge deficit on the road against No. 11 Texas in Week 8. QB Trinidad Chambliss is a great talent with a huge arm, yet the Rebels’ defense is a liability.

Ole Miss ranks 80th in points allowed per game (25.3) in 2026. They’ve surrendered 4.1 YPC and 12 rushing touchdowns against 5 SEC opponents.

Chambliss, despite his elite abilities, has not been able to avoid miscues. Ole Miss’ offense has at least 1 turnover in every game played this season, including 3 against the Longhorns.

Auburn’s defense is stout against the run, although they are susceptible to the opposing passing attack. On offense, Golesh’s scheme has led to the Tigers averaging 4.3 YPC, which he’ll definitely lean on against a weak Ole Miss run defense.

Auburn QB Byrum Brown is a true dual-threat, handling 126 carries for 3.8 YPC and 6 rushing touchdowns. He’s landing a relatively soft matchup for the first time since putting up 271 and 3 against Florida.

+11.5 is too many points to ignore. Bet on Auburn to cover on the road in Oxford.

Pick: Auburn +11.5 (-110)